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Current Gastroenterology Reports
Published in: Current Gastroenterology Reports 1/2024

07-12-2023 | Cystic Fibrosis

Neurogastroenterology and Motility Disorders of the Gastrointestinal Tract in Cystic Fibrosis

Authors: Dhiren Patel, Folashade Jose, Jason Baker, Baha Moshiree

Published in: Current Gastroenterology Reports | Issue 1/2024

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Abstract

Purpose of Review

To discuss all the various motility disorders impacting people with Cystic Fibrosis (PwCF) and provide diagnostic and management approaches from a group of pediatric and adult CF and motility experts and physiologists with experience in the management of this disease.

Recent Findings

Gastrointestinal (GI) symptoms coexist with pulmonary symptoms in PwCF regardless of age and sex. The GI manifestations include gastroesophageal reflux disease, esophageal dysmotility gastroparesis, small bowel dysmotility, small intestinal bacterial overgrowth syndrome, distal idiopathic obstruction syndrome, constipation, and pelvic floor disorders. They are quite debilitating, limiting the patients’ quality of life and affecting their nutrition and ability to socialize. This genetic disorder affects many organ systems and is chronic, potentially impacting fertility and future family planning, requiring a multidisciplinary approach.

Summary

Our review discusses the treatments of motility disorders in CF, their prevalence and pathophysiology. We have provided a framework for clinicians who care for these patients that can help to guide their clinical management.
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Metadata
Title
Neurogastroenterology and Motility Disorders of the Gastrointestinal Tract in Cystic Fibrosis
Authors
Dhiren Patel
Folashade Jose
Jason Baker
Baha Moshiree
Publication date
07-12-2023
Publisher
Springer US
Published in
Current Gastroenterology Reports / Issue 1/2024
Print ISSN: 1522-8037
Electronic ISSN: 1534-312X
DOI
https://doi.org/10.1007/s11894-023-00906-4
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