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Open Access 01-12-2021 | Cystectomy | Short Communications

RAZOR trial: analysis of 3-year follow-up: an era of robotic radical cystectomy: is it a new beginning?

Author: Satish Kumar Ranjan

Published in: African Journal of Urology | Issue 1/2021

Abstract

RAZOR (Randomized Open versus Robotic Cystectomy) trial is a phase 3 randomized control trial comparing robot-assisted laparoscopic radical cystectomy with open radical cystectomy for the treatment of bladder cancer published by Parekh et.al. Three-year follow-up analysis of this trial showed that there was no difference in overall survival, progression-free survival, and local or distant recurrence in both the group. The present report will discuss this landmark trial in brief in the context of the advantage and feasibility of robotic radical cystectomy in the developing world.

Parekh DJ, Reis IM, Castle EP, Gonzalgo ML, Woods ME, Svatek RS, Weizer AZ, Konety BR, Tollefson M, Krupski TL, Smith ND (2018) Robot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer (RAZOR): an open-label, randomised, phase 3, non-inferiority trial. The Lancet 391(10139):2525–2536CrossRef

Venkatramani V, Reis IM, Castle EP, Gonzalgo ML, Woods ME, Svatek RS et al (2020) Predictors of recurrence, and progression-free and overall survival following open versus robotic radical cystectomy: analysis from the RAZOR trial with a 3-year followup. J Urol 203:522–529CrossRef

Nix J, Smith A, Kurpad R, Nielsen ME, Wallen EM, Pruthi RS (2010) Prospective randomized controlled trial of robotic versus open radical cystectomy for bladder cancer: perioperative and pathologic results. Eur Urol 57:196–201CrossRef

Stein JP, Lieskovsky G, Cote R, Groshen S, Feng AC, Boyd S et al (2001) Radical cystectomy in the treatment of invasive bladder cancer: long-term results in 1,054 patients. J Clin Oncol 19:666–675CrossRef

Bora GS, Narain TA, Sharma AP, Mavuduru RS et al (2020) Robot-assisted surgery in India: A SWOT analysis. Indian J Urol 36:1–3PubMedPubMedCentral

Title: RAZOR trial: analysis of 3-year follow-up: an era of robotic radical cystectomy: is it a new beginning?
Author: Satish Kumar Ranjan
Publication date: 01-12-2021
Publisher: Springer Berlin Heidelberg
Keyword: Cystectomy
Published in: African Journal of Urology / Issue 1/2021
Print ISSN: 1110-5704
Electronic ISSN: 1961-9987
DOI: https://doi.org/10.1186/s12301-021-00182-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

RAZOR trial: analysis of 3-year follow-up: an era of robotic radical cystectomy: is it a new beginning?

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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