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01-08-2015 | Original Article

Cyst Gastrostomy and Necrosectomy for the Management of Sterile Walled-Off Pancreatic Necrosis: a Comparison of Minimally Invasive Surgical and Endoscopic Outcomes at a High-Volume Pancreatic Center

Authors: Mohammad Khreiss, Mazen Zenati, Amber Clifford, Kenneth K. Lee, Melissa E. Hogg, Adam Slivka, Jennifer Chennat, Andres Gelrud, Herbert J. Zeh, Georgios I. Papachristou, Amer H. Zureikat

Published in: Journal of Gastrointestinal Surgery | Issue 8/2015

Abstract

Introduction

Walled-off pancreatic necrosis (WON) is a sequela of acute necrotizing pancreatitis in 15–40 % of cases. We sought to compare the outcomes of minimally invasive surgical and endoscopic cyst gastrostomy (CG) and necrosectomy for the management for sterile WON at a tertiary care high-volume pancreas center.

Method

This is a retrospective review of patients who underwent minimally invasive surgical or endoscopic CG and necrosectomy for clinically sterile WON between 2008 and 2013. Peri-procedural outcomes including costs were analyzed and compared.

Results

Twenty patients underwent minimally invasive surgical (robotic = 14, laparoscopic = 6) CG and necrosectomy, and 20 patients underwent endoscopic treatment. The surgical cohort had a larger median cyst size and higher CCI score. For the surgical cohort, median OR time was 167.5 min, estimated blood loss was 30 ml, and 65 % underwent concomitant cholecystectomy. There was no mortality in either group and no difference in complication rates (20 %). The failure rate was similar (15 versus 10 %, P = 0.66). Although surgery was associated with a lower re-intervention rate (0 versus 1, P = 0.008), the endotherapy group was associated with shorter total LOS (inclusive of re-interventions) (7 versus 3 days, P = 0.032). The cost of the index procedure was significantly higher for the surgery group (P = 0.014); however, when considering all readmissions and re-interventions until resolution of the WON, the total cost was similar for both groups.

Conclusion

Minimally invasive surgical and endoscopic CG and necrosectomy are comparable treatments for sterile WON in terms of outcomes and overall cost. The surgical approach may be considered advantageous when a concomitant cholecystectomy is required.

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Title: Cyst Gastrostomy and Necrosectomy for the Management of Sterile Walled-Off Pancreatic Necrosis: a Comparison of Minimally Invasive Surgical and Endoscopic Outcomes at a High-Volume Pancreatic Center
Authors: Mohammad Khreiss
Mazen Zenati
Amber Clifford
Kenneth K. Lee
Melissa E. Hogg
Adam Slivka
Jennifer Chennat
Andres Gelrud
Herbert J. Zeh
Georgios I. Papachristou
Amer H. Zureikat
Publication date: 01-08-2015
Publisher: Springer US
Published in: Journal of Gastrointestinal Surgery / Issue 8/2015
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-015-2864-6

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Cyst Gastrostomy and Necrosectomy for the Management of Sterile Walled-Off Pancreatic Necrosis: a Comparison of Minimally Invasive Surgical and Endoscopic Outcomes at a High-Volume Pancreatic Center

Abstract

Introduction

Method

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Method

Results

Conclusion

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