Top

Published in:

01-03-2015 | Letter to the Editor

Cutaneous carcinosarcoma and the EMT: to transition, or not to transition? That is the question

Authors: Alberto Paniz-Mondolfi, Rajesh Singh, George Jour, Mandana Mahmoodi, A. Hafeez Diwan, Bedia A. Barkoh, Ronald Cason, Yve Huttenbach, Gustavo Benaim, John Galbincea, Rajyalakshmi Luthra

Published in: Virchows Archiv | Issue 3/2015

Excerpt

To the editor: …

Zidar N, Gale N (2015). Carcinosarcoma and spindle cell carcinoma—monoclonal neoplasms undergoing epithelial-mesenchymal transition. Virchows Arch in this issue

Thiery JP, Sleeman JP (2006) Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol 7:131–142CrossRefPubMed

Guarino M, Rubino B, Ballabio G (2007) The role of epithelial-mesenchymal transition in cancer pathology. Pathology 39:305–318CrossRefPubMed

Tarin D, Thompson EW, Newgreen DF (2005) The fallacy of epithelial mesenchymal transition in neoplasia. Cancer Res 65:5996–6000CrossRefPubMed

Paniz-Mondolfi A, Singh R, Jour G, Mahmoodi M, Hafeez Diwan A, Barkoh BA, Cason R, Huttenbach Y, Benaim G, Galbincea J, Luthra R (2014) Cutaneous carcinosarcoma: further insights into its mutational landscape through massive parallel genome sequencing. Virchows Arch 465:339–350CrossRefPubMed

Paniz Mondolfi AE, Jour G, Johnson M, Reidy J, Cason RC, Barkoh BA, Benaim G, Singh R, Luthra R (2013) Primary cutaneous carcinosarcoma: insights into its clonal origin and mutational pattern expression analysis through next-generation sequencing. Hum Pathol 44:2853–2860CrossRefPubMed

Grille SJ, Bellacosa A, Upson J (2003) The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines. Cancer Res 63:2172–2178PubMed

Jechlinger M, Sommer A, Moriggl R, Seither P, Kraut N, Capodiecci P, Donovan M, Cordon-Cardo C, Beug H, Grünert S (2006) Autocrine PDGFR signaling promotes mammary cancer metastasis. J Clin Invest 116:1561–1570CrossRefPubMedCentralPubMed

Title: Cutaneous carcinosarcoma and the EMT: to transition, or not to transition? That is the question
Authors: Alberto Paniz-Mondolfi
Rajesh Singh
George Jour
Mandana Mahmoodi
A. Hafeez Diwan
Bedia A. Barkoh
Ronald Cason
Yve Huttenbach
Gustavo Benaim
John Galbincea
Rajyalakshmi Luthra
Publication date: 01-03-2015
Publisher: Springer Berlin Heidelberg
Published in: Virchows Archiv / Issue 3/2015
Print ISSN: 0945-6317
Electronic ISSN: 1432-2307
DOI: https://doi.org/10.1007/s00428-015-1718-7

At a glance: The STEP trials

Springer Medicine

Cutaneous carcinosarcoma and the EMT: to transition, or not to transition? That is the question

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Issue 3/2015

Pathologic-radiologic correlation in evaluation of retroareolar margin in nipple-sparing mastectomy

WRN protein as a novel erythroblast immunohistochemical marker with applications for the diagnosis of Werner syndrome

Carcinosarcoma and spindle cell carcinoma—monoclonal neoplasms undergoing epithelial-mesenchymal transition

Follicular variant of peripheral T cell lymphoma with mediastinal involvement in a child: a case report

Tumor evolution and progression in multifocal and paired non-invasive/invasive urothelial carcinoma

Mammary analogue secretory carcinoma of salivary glands: a new entity associated with ETV6 gene rearrangement