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BMC Public Health
Published in: BMC Public Health 1/2011

Open Access 01-12-2011 | Research article

Cumulative smoking exposure, duration of smoking cessation, and peripheral arterial disease in middle-aged and older Korean men

Authors: Young-Hoon Lee, Min-Ho Shin, Sun-Seog Kweon, Jin-Su Choi, Jung-Ae Rhee, Hye-Ran Ahn, Woo-Jun Yun, So-Yeon Ryu, Bok-Hee Kim, Hae-Sung Nam, Seul-Ki Jeong, Kyeong-Soo Park

Published in: BMC Public Health | Issue 1/2011

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Abstract

Background

We investigated the association of cumulative smoking exposure and duration of smoking cessation with peripheral arterial disease (PAD).

Methods

The study population consisted of 2517 community-dwelling Korean men aged 50 years and older. Information on smoking characteristics such as smoking status, pack-years of smoking, and years since quitting smoking was collected using a standardized questionnaire. PAD was defined as an ankle-brachial index (ABI) less than 0.90 in either leg.

Results

The odds ratio (OR, 95% confidence interval) of PAD was 2.31 (1.20-4.42) for former smokers and 4.30 (2.13-8.66) for current smokers, after adjusting for other cardiovascular risk factors. There was a significant dose-response relationship between pack-years of smoking and PAD. Compared with those who had never smoked, the multivariate-adjusted ORs of PAD for smokers of 0.1-20.0, 20.1-40.0, and >40.0 pack-years were 2.15 (1.06-4.38), 2.24 (1.08-4.65), and 2.93 (1.41-6.09), respectively. There was a significant decrease in PAD risk as the years since quitting smoking increased. The multivariate-adjusted ORs of PAD for 11-20 and ≥21 years smoking cessation were 0.41 (0.19-0.86) and 0.49 (0.24-0.98), compared with current smokers.

Conclusions

Cumulative smoking exposure and duration of smoking cessation were significantly associated with PAD in middle aged and older Korean men.
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Metadata
Title
Cumulative smoking exposure, duration of smoking cessation, and peripheral arterial disease in middle-aged and older Korean men
Authors
Young-Hoon Lee
Min-Ho Shin
Sun-Seog Kweon
Jin-Su Choi
Jung-Ae Rhee
Hye-Ran Ahn
Woo-Jun Yun
So-Yeon Ryu
Bok-Hee Kim
Hae-Sung Nam
Seul-Ki Jeong
Kyeong-Soo Park
Publication date
01-12-2011
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2011
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-11-94

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