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Published in: Aesthetic Plastic Surgery 5/2024

18-05-2023 | Cryotherapy | Original Article

Comparison of the Effectiveness of Different Methods for Pain Reduction During Injection Procedures in the Frontalis Muscle

Authors: Alessandra Maria Santos Athadeu, Mariana Barbosa Câmara-Souza, Rodrigo Lorenzi Poluha, Vivian Werneck Heredia Alvim Soares, Bryanne Brissian de Souza Nobre, Cristina Manso, André Mariz de Almeida, Giancarlo De la Torre Canales

Published in: Aesthetic Plastic Surgery | Issue 5/2024

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Abstract

Background

Forehead aesthetic injections are a well-known source of discomfort, and many analgesic non-invasive techniques have been proposed to ameliorate pain. However, no study has compared all these techniques for aesthetic purposes. Therefore, this study aimed to compare the effectiveness of topical cream anesthesia, vibratory stimulus, cryotherapy, pressure, and even no intervention, on pain during and immediately after injection, when considering aesthetic injections in the forehead.

Methods

Seventy patients were selected and had their foreheads divided into 5 parts, which received four different analgesic techniques, and one control zone was added. A numeric rating scale was used to assess pain, two direct questions were asked to evaluate patients’ preference and discomfort with the techniques, and the adverse events were quantified. The injections were performed in the same sequence, with three minutes of rest between them and in a single session. Comparisons among analgesic methods for pain relief were performed by the one-way analysis of variance (ANOVA), considering a significance level of 5%.

Results

No significant differences were found among the analgesic methods, and between the methods and the control zone, both during and immediately after the injections (p > 0.05). The preferred method for pain relief was the use of topical anesthetic cream (47%), while the most uncomfortable technique was manual distraction (pressure) (36%). Only one patient reported an adverse event.

Conclusions

No analgesic method to diminish pain was superior to the others or was better than no method. Nevertheless, the topical anesthetic cream was the preferred technique, causing less discomfort.

Level of Evidence III

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.​springer.​com/​00266.
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Metadata
Title
Comparison of the Effectiveness of Different Methods for Pain Reduction During Injection Procedures in the Frontalis Muscle
Authors
Alessandra Maria Santos Athadeu
Mariana Barbosa Câmara-Souza
Rodrigo Lorenzi Poluha
Vivian Werneck Heredia Alvim Soares
Bryanne Brissian de Souza Nobre
Cristina Manso
André Mariz de Almeida
Giancarlo De la Torre Canales
Publication date
18-05-2023
Publisher
Springer US
Published in
Aesthetic Plastic Surgery / Issue 5/2024
Print ISSN: 0364-216X
Electronic ISSN: 1432-5241
DOI
https://doi.org/10.1007/s00266-023-03399-8

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