Published in:
01-02-2016 | Editorial
Crude reality versus data manipulation: is the glass always crystal clear?
Authors:
Heleen M. Oudemans-van Straaten, Jean-Jacques Parienti
Published in:
Intensive Care Medicine
|
Issue 2/2016
Login to get access
Excerpt
A patient with chronic dialysis was admitted to the ICU for septic shock and died. What would have been the outcome if this patient had not been exposed to chronic dialysis prior to septic shock? In the real world, the identical situation never occurs twice at the same time, which creates a 50 % of missing data compared to the counterfactual world, because removing the exposure to see what happens is impossible. The variability of factors associated with exposure and outcome has the potential to confound the variability in the outcome associated with the variability of exposure. …