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01-10-2013 | Commentary

Critical care rehabilitation trials: the importance of ‘usual care’

Authors: Ann Parker, Kian M Tehranchi, Dale M Needham

Published in: Critical Care | Issue 5/2013

Abstract

Denehy and colleagues conducted a novel randomized controlled trial evaluating a rehabilitation intervention starting in the ICU and continuing through the outpatient setting, with 1 year longitudinal follow-up. While the intervention did not demonstrate improved patient outcomes, this study illustrates important issues regarding ‘usual care’ control groups in clinical trials.

Denehy L, Skinner EH, Edbrooke L, Haines K, Warrillow S, Hawthorne G, Gough K, Hoorn SV, Morris ME, Berney S: Exercise rehabilitation for patients with critical illness: a randomized controlled trial with 12 months follow up. Crit Care 2013, 17: R156. 10.1186/cc12835PubMedCentralCrossRefPubMed

Burtin C, Clerckx B, Robbeets C, Ferdinande P, Langer D, Troosters T, Hermans G, Decramer M, Gosselink R: Early exercise in critically ill patients enhances short-term functional recovery. Crit Care Med 2009, 37: 2499-2505. 10.1097/CCM.0b013e3181a38937CrossRefPubMed

Schweickert WD, Pohlman MC, Pohlman AS, Nigos C, Pawlik AJ, Esbrook CL, Spears L, Miller M, Franczyk M, Deprizio D, Schmidt GA, Bowman A, Barr R, McCallister KE, Hall JB, Kress JP: Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. Lancet 2009, 373: 1874-1882. 10.1016/S0140-6736(09)60658-9CrossRefPubMed

Morris PE, Goad A, Thompson C, Taylor K, Harry B, Passmore L, Ross A, Anderson L, Baker S, Sanchez M, Penley L, Howard A, Dixon L, Leach S, Small R, Hite RD, Haponik E: Early intensive care unit mobility therapy in the treatment of acute respiratory failure. Crit Care Med 2008, 36: 2238-2243. 10.1097/CCM.0b013e318180b90eCrossRefPubMed

Herridge MS, Tansey CM, Matté A, Tomlinson G, Diaz-Granados N, Cooper A, Guest CB, Mazer CD, Mehta S, Stewart TE, Kudlow P, Cook D, Slutsky AS, Cheung AM, Canadian Critical Care Trials Group: Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med 2011, 364: 1293-1304. 10.1056/NEJMoa1011802CrossRefPubMed

Desai SV, Law TJ, Needham DM: Long-term complications of critical care. Crit Care Med 2011, 39: 371-379. 10.1097/CCM.0b013e3181fd66e5CrossRefPubMed

Bienvenu OJ, Colantuoni E, Mendez-Tellez PA, Dinglas VD, Shanholtz C, Husain N, Dennison CR, Herridge MS, Pronovost PJ, Needham DM: Depressive symptoms and impaired physical function after acute lung injury: a 2-year longitudinal study. Am J Respir Crit Care Med 2012, 185: 517-524. 10.1164/rccm.201103-0503OCPubMedCentralCrossRefPubMed

Barnato AE, Albert SM, Angus DC, Lave JR, Degenholtz HB: Disability among elderly survivors of mechanical ventilation. Am J Respir Crit Care Med 2011, 183: 1037-1042. 10.1164/rccm.201002-0301OCPubMedCentralCrossRefPubMed

Berney S, Haines K, Skinner EH, Denehy L: Safety and feasibility of an exercise prescription approach to rehabilitation across the continuum of care for survivors of critical illness. Phys Ther 2012, 92: 1524-1535. 10.2522/ptj.20110406CrossRefPubMed

10.

Berney S, Harrold M, Webb SA, Seppelt I, Patman S, Thomas PJ, Denehy L: ICU mobility practices in Australia and New Zealand: a point prevalence study. Crit Care Resusc in press

11.

Thompson BT, Schoenfeld D: Usual care as the control group in clinical trials of nonpharmacologic interventions. Proc Am Thoracic Soc 2007, 4: 577-582. 10.1513/pats.200706-072JKCrossRef

12.

Hart T, Bagiella E: Design and implementation of clinical trials in rehabilitation research. Arch Phys Med Rehab 2012, 93: S117-S126. 10.1016/j.apmr.2011.11.039CrossRef

13.

Minneci PC, Eichacker PQ, Danner RL, Banks SM, Natanson C, Deans KJ: The importance of usual care control groups for safety monitoring and validity during critical care research. Intensive Care Med 2008, 34: 942-947. 10.1007/s00134-008-0999-6CrossRefPubMed

14.

Needham DM, Davidson J, Cohen H, Hopkins RO, Weinert C, Wunsch H, Zawistowski C, Bemis-Dougherty A, Berney SC, Bienvenu OJ, Brady SL, Brodsky MB, Denehy L, Elliott D, Flatley C, Harabin AL, Jones C, Louis D, Meltzer W, Muldoon SR, Palmer JB, Perme C, Robinson M, Schmidt DM, Scruth E, Spill GR, Storey CP, Render M, Votto J, Harvey MA: Improving long-term outcomes after discharge from intensive care unit: report from a stakeholders’ conference. Crit Care Med 2012, 40: 502-509. 10.1097/CCM.0b013e318232da75CrossRefPubMed

Title: Critical care rehabilitation trials: the importance of ‘usual care’
Authors: Ann Parker
Kian M Tehranchi
Dale M Needham
Publication date: 01-10-2013
Publisher: BioMed Central
Published in: Critical Care / Issue 5/2013
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/cc12884

At a glance: The STEP trials

Springer Medicine

Critical care rehabilitation trials: the importance of ‘usual care’

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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