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Neurological Sciences

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Open Access 10-05-2022 | COVID-19 | COVID-19

A longitudinal study on the effects of COVID-19 pandemic on non-motor symptoms in Parkinson’s disease

Authors: Alfonsina D’Iorio, Chiara Baiano, Giovanna Maraucci, Carmine Vitale, Marianna Amboni, Gabriella Santangelo

Published in: Neurological Sciences | Issue 8/2022

Abstract

Introduction

The COVID-19 pandemic led to psychological consequences on people’s mental health, representing a condition of increased vulnerability for the weakest sections of population, including elderly patients with Parkinson’s disease (PD).

This longitudinal study aimed at exploring the impact of the most frequent non-motor symptoms and their contribute on health-related quality of life of PD patients after the COVID-19 outbreak, in comparison with the pre-pandemic status.

Methods

Forty-two non-demented PD patients underwent a first assessment between December 2018 and January 2020 (T0). Then, between March and May 2021 (T1), they were contacted again and asked to complete the second assessment. Levels of global functioning, several non-motor symptoms (i.e. depression, apathy, anxiety, anhedonia) and health-related quality of life were investigated.

Results

Results of the the paired Wilcoxon signed-rank test showed that at T1, PD patients scored lower on the emotional subscale of the DAS, Z = − 2.49; p = 0.013; Cohen d_z = 0.691. Higher scores of the TEPS total score, Z = − 2.38; p = 0.025; Cohen d_z = 0.621, and LEDD, Z = − 2.63; p = 0.008; Cohen d_z = 0.731, were also reported at T1.

Conclusion

The present study suggested that self-isolation at home might lead to a reduction of apathy and anhedonia in PD patients due to the increase in social support provided by families during COVID-19 restrictions. This evidence brings out the need of a consistent and persistent social support which might be represented by caregivers or/and social assistive robotics.

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Title: A longitudinal study on the effects of COVID-19 pandemic on non-motor symptoms in Parkinson’s disease
Authors: Alfonsina D’Iorio
Chiara Baiano
Giovanna Maraucci
Carmine Vitale
Marianna Amboni
Gabriella Santangelo
Publication date: 10-05-2022
Publisher: Springer International Publishing
Keywords: COVID-19
Parkinson's Disease
Anxiety
Published in: Neurological Sciences / Issue 8/2022
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-022-06112-w

Keynote webinar | Spotlight on medication adherence

Springer Medicine

A longitudinal study on the effects of COVID-19 pandemic on non-motor symptoms in Parkinson’s disease

Abstract

Introduction

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusion

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