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Published in: World Journal of Surgery 4/2021

01-04-2021 | COVID-19 | Original Scientific Report

Impact of COVID-19 Restrictions on Demographics and Outcomes of Patients Undergoing Medically Necessary Non-Emergent Surgeries During the Pandemic

Authors: Adrienne B. Shannon, Jeffrey L. Roberson, Luke Keele, Tina Bharani, Yun Song, John T. Miura, Rachel R. Kelz, Daniel T. Dempsey, Lee A. Fleisher, Ronald P. DeMatteo, Giorgos C. Karakousis

Published in: World Journal of Surgery | Issue 4/2021

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Abstract

Background

The COVID-19 pandemic has resulted in large-scale healthcare restrictions to control viral spread, reducing operating room censuses to include only medically necessary surgeries. The impact of restrictions on which patients undergo surgical procedures and their perioperative outcomes is less understood.

Methods

Adult patients who underwent medically necessary surgical procedures at our institution during a restricted operative period due to the COVID-19 pandemic (March 23-April 24, 2020) were compared to patients undergoing procedures during a similar time period in the pre-COVID-19 era (March 25-April 26, 2019). Cardinal matching and differences in means were utilized to analyze perioperative outcomes.

Results

857 patients had surgery in 2019 (pre-COVID-19) and 212 patients had surgery in 2020 (COVID-19). The COVID-19 era cohort had a higher proportion of patients who were male (61.3% vs. 44.5%, P < 0.0001), were White (83.5% vs. 68.7%, P < 0.001), had private insurance (62.7% vs. 54.3%, p 0.05), were ASA classification 4 (10.9% vs. 3%, P < 0.0001), and underwent oncologic procedures (69.3% vs. 42.7%, P < 0.0001). Following 1:1 cardinal matching, COVID-19 era patients (N = 157) had a decreased likelihood of discharge to a nursing facility (risk difference-8.3, P < 0.0001) and shorter median length of stay (risk difference-0.6, p 0.04) compared to pre-COVID-19 era patients. There was no difference between the two patient cohorts in overall morbidity and 30-day readmission.

Conclusions

COVID-19 restrictions on surgical operations were associated with a change in the racial and insurance demographics in patients undergoing medically necessary surgical procedures but were not associated with worse postoperative morbidity. Further study is necessary to better identify the causes for patient demographic differences.
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Literature
1.
go back to reference Zhu N, Zhang D, Wang W, Li X, Yang B, Song J et al (2020) A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med 382:727–733CrossRef Zhu N, Zhang D, Wang W, Li X, Yang B, Song J et al (2020) A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med 382:727–733CrossRef
2.
go back to reference Yu P, Zhu J, Zhang Z, Han Y (2019) A familial cluster of infection associated with the 2019 novel coronavirus indicating possible person-to-person transmission during the incubation period. J Infect Dis 2020(221):1757–1761 Yu P, Zhu J, Zhang Z, Han Y (2019) A familial cluster of infection associated with the 2019 novel coronavirus indicating possible person-to-person transmission during the incubation period. J Infect Dis 2020(221):1757–1761
4.
go back to reference Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J et al (2020) Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan. China JAMA 323(11):1061–1069CrossRef Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J et al (2020) Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan. China JAMA 323(11):1061–1069CrossRef
5.
go back to reference Guan W, Ni Z, Hu Y, Liang W, Ou C, He J et al (2020) Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 382:1708–1720CrossRef Guan W, Ni Z, Hu Y, Liang W, Ou C, He J et al (2020) Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 382:1708–1720CrossRef
6.
go back to reference Holshue ML, DeBolt C, Lindquist S, Lofy KH, Wiesman J, Bruce H et al (2020) First case of 2019 novel coronavirus in the USA. N Engl J Med 382:929–936CrossRef Holshue ML, DeBolt C, Lindquist S, Lofy KH, Wiesman J, Bruce H et al (2020) First case of 2019 novel coronavirus in the USA. N Engl J Med 382:929–936CrossRef
14.
go back to reference Stahel PF (2020) How to risk-stratify elective surgery during the COVID-19 pandemic? Patient Saf Surg 14(8):1–4 Stahel PF (2020) How to risk-stratify elective surgery during the COVID-19 pandemic? Patient Saf Surg 14(8):1–4
21.
24.
go back to reference Hooper MW, Nápoles AM, EJ Pérez-Stabl (2020) COVID-19 and racial/ethnic disparities. JAMA 323(24):2466–2467 Hooper MW, Nápoles AM, EJ Pérez-Stabl (2020) COVID-19 and racial/ethnic disparities. JAMA 323(24):2466–2467
26.
go back to reference Zubizarreta JR, Paredes RD, Rosenbaum PR (2014) Matching for balance, pairing for heterogeneity in an observational study of the effectiveness of for-profit and not-for-profit high schools in Chile. Ann Appl Stat 8(1):204–231CrossRef Zubizarreta JR, Paredes RD, Rosenbaum PR (2014) Matching for balance, pairing for heterogeneity in an observational study of the effectiveness of for-profit and not-for-profit high schools in Chile. Ann Appl Stat 8(1):204–231CrossRef
27.
go back to reference Rosenbaum PR, Ross RN, Silber JH (2007) Mimimum distance matched sampling with fine balance in an observational study of treatmetnt for ovarian cancer. J Am Stat Assoc 102(477):75–83CrossRef Rosenbaum PR, Ross RN, Silber JH (2007) Mimimum distance matched sampling with fine balance in an observational study of treatmetnt for ovarian cancer. J Am Stat Assoc 102(477):75–83CrossRef
28.
go back to reference Silber JH, Rosenbaum PR, Trudeau ME et al (2001) Multivariate matching and bias reduction in the surgical outcomes study. Med Care 39(10):1048–1064CrossRef Silber JH, Rosenbaum PR, Trudeau ME et al (2001) Multivariate matching and bias reduction in the surgical outcomes study. Med Care 39(10):1048–1064CrossRef
29.
go back to reference Rosenbaum PR, Rubin DB (1985) Constructing a control group using multivariate matched sampling methods. Am Stat 39(1):33–38 Rosenbaum PR, Rubin DB (1985) Constructing a control group using multivariate matched sampling methods. Am Stat 39(1):33–38
30.
go back to reference Cochran WG, Rubin DB (1973) Controlling bias in observational studies. Sankyha-Indian J Stat Ser A 35:417–446 Cochran WG, Rubin DB (1973) Controlling bias in observational studies. Sankyha-Indian J Stat Ser A 35:417–446
31.
go back to reference Bishop YM, Fienberg SE, Holland PW, Light RJ, Mosteller F (1977) Book review: discrete multivariate analysis: theory and practice. Appl Psychol Meas 1:297–306CrossRef Bishop YM, Fienberg SE, Holland PW, Light RJ, Mosteller F (1977) Book review: discrete multivariate analysis: theory and practice. Appl Psychol Meas 1:297–306CrossRef
32.
go back to reference Rosenbaum PR (2007) Sensitivity analysis for m-estimates, tests, and confidence intervals in matched observational studies. Biometrics 63:456–464CrossRef Rosenbaum PR (2007) Sensitivity analysis for m-estimates, tests, and confidence intervals in matched observational studies. Biometrics 63:456–464CrossRef
33.
go back to reference Maritz J (1979) A note on exact robust confidence intervals for location. Biometrika 66:163–170CrossRef Maritz J (1979) A note on exact robust confidence intervals for location. Biometrika 66:163–170CrossRef
35.
go back to reference R Core Team (2019) R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. Published 2019. https://www.R-project.org. Accessed 1 July 2019 R Core Team (2019) R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. Published 2019. https://​www.​R-project.​org. Accessed 1 July 2019
36.
go back to reference Lei S, Jiang F, Su W, Chen C, Chen J, Mei W et al (2020) Clinical characteristics and outcomes of patients undergoing surgery during the incubation period of COVID-19 infection. E Clin Med 21:100331 Lei S, Jiang F, Su W, Chen C, Chen J, Mei W et al (2020) Clinical characteristics and outcomes of patients undergoing surgery during the incubation period of COVID-19 infection. E Clin Med 21:100331
37.
go back to reference Liang W, Guan W, Chen R, Wang W, Li J, Xu K et al (2020) Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China. The Lancet 21:335–337CrossRef Liang W, Guan W, Chen R, Wang W, Li J, Xu K et al (2020) Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China. The Lancet 21:335–337CrossRef
39.
go back to reference Eberly LA, Khatana SAM, Nathan AS, Snider C, Julien HM, Deleener ME et al (2020) Telemedicine outpatient cardiovascular care during the COVID-19 pandemic: bridging or opening the digital divide? Circulation 142:510–512CrossRef Eberly LA, Khatana SAM, Nathan AS, Snider C, Julien HM, Deleener ME et al (2020) Telemedicine outpatient cardiovascular care during the COVID-19 pandemic: bridging or opening the digital divide? Circulation 142:510–512CrossRef
40.
go back to reference Chauhan V, Galwankar S, Arquilla B, Garg M, Di Somma S, El-Menyar, et al (2020) Novel coronavirus (COVID-19): leveraging telemedicine to optimize care while minimizing exposures and viral transmission. J Emerg Trauma Shock 13(1):20–24PubMedPubMedCentral Chauhan V, Galwankar S, Arquilla B, Garg M, Di Somma S, El-Menyar, et al (2020) Novel coronavirus (COVID-19): leveraging telemedicine to optimize care while minimizing exposures and viral transmission. J Emerg Trauma Shock 13(1):20–24PubMedPubMedCentral
45.
go back to reference Minkoff H (2020) You don’t have to be infected to suffer: COVID-19 and racial disparities in severe maternal morbidity and mortality. Am J Perinatol 37:1052–1054CrossRef Minkoff H (2020) You don’t have to be infected to suffer: COVID-19 and racial disparities in severe maternal morbidity and mortality. Am J Perinatol 37:1052–1054CrossRef
46.
go back to reference COVIDSurg Collaborative (2020) Head and neck cancer surgery during the COVID-19 pandemic: An international, multicenter, observational cohort study. Cancer COVIDSurg Collaborative (2020) Head and neck cancer surgery during the COVID-19 pandemic: An international, multicenter, observational cohort study. Cancer
47.
go back to reference COVIDSurg Collaborative. Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic. Colorectal Dis. 2020;00:1–18 COVIDSurg Collaborative. Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic. Colorectal Dis. 2020;00:1–18
48.
go back to reference Singhal R, Tahrani AA, Ludwig C, Mahawar K, GENEVA collaborators et al. (2021) Global 30-day outcomes after bariatric surgery during the COVID-19 pandemic (GENEVA): an international cohort study. The Lancet 9:7–9 Singhal R, Tahrani AA, Ludwig C, Mahawar K, GENEVA collaborators et al. (2021) Global 30-day outcomes after bariatric surgery during the COVID-19 pandemic (GENEVA): an international cohort study. The Lancet 9:7–9
49.
go back to reference Zhan Y, Zhao S, Yuan J, Liu H, Liu Y, Gui L et al (2020) Prevalence and influencing factors on fatigue of first-line nurses combating with COVID-19 in China: a descriptive cross-sectional study. Curr Med Sci 40(4):1–11CrossRef Zhan Y, Zhao S, Yuan J, Liu H, Liu Y, Gui L et al (2020) Prevalence and influencing factors on fatigue of first-line nurses combating with COVID-19 in China: a descriptive cross-sectional study. Curr Med Sci 40(4):1–11CrossRef
50.
go back to reference Lai J, Ma S, Wang Y, Cai Z, Hu J, Wei N et al (2020) Factors associated with mental health outcomes among health care workers exposed to coronavirus disease 2019. JAMA Netw Open 3(3):e203976CrossRef Lai J, Ma S, Wang Y, Cai Z, Hu J, Wei N et al (2020) Factors associated with mental health outcomes among health care workers exposed to coronavirus disease 2019. JAMA Netw Open 3(3):e203976CrossRef
51.
go back to reference Lu W, Wang H, Lin Y, Li L (2020) Psychological status of medical workforce during the COVID-19 pandemic: a cross-sectional study. Psych Res 288: 112936 Lu W, Wang H, Lin Y, Li L (2020) Psychological status of medical workforce during the COVID-19 pandemic: a cross-sectional study. Psych Res 288: 112936
52.
go back to reference To KB, Kamdar NS, Patil P, Collins SD, Seese E, Krapohl GL et al (2019) Acute care surgery model and outcomes in emergency general surgery. J Am Coll Surg 228:21–28CrossRef To KB, Kamdar NS, Patil P, Collins SD, Seese E, Krapohl GL et al (2019) Acute care surgery model and outcomes in emergency general surgery. J Am Coll Surg 228:21–28CrossRef
53.
go back to reference Sharoky CE, Bailey EA, Sellers MM, Kaufman EJ, Sinnamon AJ, Wirtalla CJ et al (2017) Outcomes of hospitalized patients undergoing emergency general surgery remote from admission. Surgery 162:612–619CrossRef Sharoky CE, Bailey EA, Sellers MM, Kaufman EJ, Sinnamon AJ, Wirtalla CJ et al (2017) Outcomes of hospitalized patients undergoing emergency general surgery remote from admission. Surgery 162:612–619CrossRef
Metadata
Title
Impact of COVID-19 Restrictions on Demographics and Outcomes of Patients Undergoing Medically Necessary Non-Emergent Surgeries During the Pandemic
Authors
Adrienne B. Shannon
Jeffrey L. Roberson
Luke Keele
Tina Bharani
Yun Song
John T. Miura
Rachel R. Kelz
Daniel T. Dempsey
Lee A. Fleisher
Ronald P. DeMatteo
Giorgos C. Karakousis
Publication date
01-04-2021
Publisher
Springer International Publishing
Keyword
COVID-19
Published in
World Journal of Surgery / Issue 4/2021
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-021-05958-z

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