Published in:
01-02-2004 | Poster presentation
Cortisol deficiency in critically ill patients after major trauma
Authors:
G Schleicher, G Richards
Published in:
Critical Care
|
Special Issue 1/2004
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Excerpt
Severe injury with activation of the systemic inflammatory response syndrome stimulates the release of cortisol from the adrenal cortex. Relative cortisol insufficiency is well described in critically ill patients, especially in severe sepsis, and is associated with increased mortality. There is conflicting data regarding the effect of major trauma and haemorrhagic shock on endogenous cortisol levels and the effects of early relative cortisol deficiency. …