Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Clinical Orthopaedics and Related Research®
Published in: Clinical Orthopaedics and Related Research® 3/2017

01-03-2017 | CORR Insights

CORR Insights®: Exposure to Secondhand Smoke Impairs Fracture Healing in Rats

Author: Jaimo Ahn, MD, PhD, FACS

Published in: Clinical Orthopaedics and Related Research® | Issue 3/2017

Login to get access

Excerpt

We do not need double-blind crossover randomized clinical trials to understand that smoking causes cancer. Though we are not “lung doctors or cancer doctors” (as I tell my patients), we understand that when the preponderance of clinical results—along with experimental and mechanistic data—strongly indicate a detrimental affect, we scientifically accept those conclusions and use them to guide and treat our patients. …
Literature
1.
Beyth S, Mosheiff R, Safran O, Daskal A, Liebergall M. Cigarette smoking is associated with a lower concentration of CD105(+) bone marrow progenitor cells. Bone Marrow Res. 2015;2015:914935.CrossRefPubMedPubMedCentral
2.
Dohnke B, Ziemann C, Will KE, Weiss-Gerlach E, Spies CD. Do hospital treatments represent a ‘teachable moment’ for quitting smoking? A study from a stage-theoretical perspective. Psychol Health. 2012;27:1291–1307.CrossRefPubMed
3.
El-Zawawy HB, Gill CS, Wright RW, Sandell LJ. Smoking delays chondrogenesis in a mouse model of closed tibial fracture healing. J Orthop Res. 2006;24:2150–2158.CrossRefPubMed
4.
Flocke SA, Clark E, Antognoli E, Mason MJ, Lawson PJ, Smith S, Cohen DJ. Teachable moments for health behavior change and intermediate patient outcomes. Patient Educ Couns. 2014;96:43–49.CrossRefPubMedPubMedCentral
5.
Fonarow GC. In-hospital initiation of statins: taking advantage of the ‘teachable moment’. Cleve Clin J Med. 2003;70:502, 504–506.
6.
Glasgow RE, Stevens VJ, Vogt TM, Mullooly JP, Lichtenstein E. Changes in smoking associated with hospitalization: Quit rates, predictive variables, and intervention implications. Am J Health Promot. 1991;6:24–29.CrossRefPubMed
7.
Iqbal J, Sun L, Cao J, Yuen T, Lu P, Bab I, Leu NA, Srinivasan S, Wagage S, Hunter CA, Nebert DW, Zaidi M, Avadhani NG. Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymes. Proc Natl Acad Sci U S A. 2013;110:11115–11120.CrossRefPubMedPubMedCentral
8.
Kanneganti P, Harris JD, Brophy RH, Carey JL, Lattermann C, Flanigan DC. The effect of smoking on ligament and cartilage surgery in the knee: A systematic review. Am J Sports Med. 2012;40:2872–2878.CrossRefPubMedPubMedCentral
9.
Kung MH, Yukata K, O’Keefe RJ, Zuscik MJ. Aryl hydrocarbon receptor-mediated impairment of chondrogenesis and fracture healing by cigarette smoke and benzo(a)pyrene. J Cell Physiol. 2012;227:1062–1070.CrossRefPubMedPubMedCentral
10.
McBride CM, Emmons KM, Lipkus IM. Understanding the potential of teachable moments: the case of smoking cessation. Health Educ Res. 2003;18:156–170.CrossRefPubMed
11.
Patel RA, Wilson RF, Patel PA, Palmer RM. The effect of smoking on bone healing: A systematic review. Bone J Res. 2013;2:102–111.CrossRef
12.
Rothem DE, Rothem L, Dahan A, Eliakim R, Soudry M. Nicotinic modulation of gene expression in osteoblast cells, MG-63. Bone. 2011;48:903–909.CrossRefPubMed
13.
Santiago-Torres J, Flanigan DC, Butler RB, Bishop JY. The effect of smoking on rotator cuff and glenoid labrum surgery: A systematic review. Am J Sports Med. 2015;43:745–751.CrossRefPubMed
14.
Scolaro JA, Schenker ML, Yannascoli S, Baldwin K, Mehta S, Ahn J. Cigarette smoking increases complications following fracture: A systematic review. J Bone Joint Surg Am. 2014;96:674–681.CrossRefPubMed
Metadata
Title
CORR Insights®: Exposure to Secondhand Smoke Impairs Fracture Healing in Rats
Author
Jaimo Ahn, MD, PhD, FACS
Publication date
01-03-2017
Publisher
Springer US
Published in
Clinical Orthopaedics and Related Research® / Issue 3/2017
Print ISSN: 0009-921X
Electronic ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-016-5217-1

Other articles of this Issue 3/2017

Clinical Orthopaedics and Related Research® 3/2017 Go to the issue

Symposium: 2015 Meetings of the Musculoskeletal Tumor Society and the International Society of Limb Salvage

Has the Level of Evidence of Podium Presentations at the Musculoskeletal Tumor Society Annual Meeting Changed Over Time?

Symposium: 2015 Meetings of the Musculoskeletal Tumor Society and the International Society of Limb Salvage

Reconstruction After Hemipelvectomy With the Ice-Cream Cone Prosthesis: What Are the Short-term Clinical Results?

Symposium: 2015 Meetings of the Musculoskeletal Tumor Society and the International Society of Limb Salvage

How Does the Level of Nerve Root Resection in En Bloc Sacrectomy Influence Patient-Reported Outcomes?

CORR Insights

CORR Insights®: How Does the Level of Nerve Root Resection in En Bloc Sacrectomy Influence Patient-Reported Outcomes?

Erratum

Erratum to: What Is the Role of Allogeneic Cortical Strut Grafts in the Treatment of Fibrous Dysplasia of the Proximal Femur?

Symposium: 2015 Meetings of the Musculoskeletal Tumor Society and the International Society of Limb Salvage

Is It Possible and Safe to Perform Acetabular-preserving Resections for Malignant Neoplasms of the Periacetabular Region?