Published in:
Open Access
01-12-2011 | Poster presentation
Coronary flow reserve correlates with right ventricular dysfunction and predicts right heart failure in patients with pulmonary arterial hypertension
Authors:
Jan Skrok, Monda L Shehata, Stephen Mathai, Miguel Santaularia Tomas, Sukhminder Singh, Reda E Girgis, James O Mudd, Danielle Boyce, Noah Lechtzin, Joao AC Lima, David A Bluemke, Paul M Hassoun, Jens Vogel-Claussen
Published in:
Journal of Cardiovascular Magnetic Resonance
|
Special Issue 1/2011
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Excerpt
In pulmonary arterial hypertension (PAH) increased pressure and resistance in the pulmonary vascular bed cause right ventricular (RV) hypertrophy with increased myocardial oxygen demand. Studies in animals with RV hypertrophy demonstrated maintained resting but reduced stress perfusion and coronary perfusion reserve, which may contribute to RV failure. …