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Open Access 01-12-2015 | Oral presentation
Controversies of the assesment and management of polycystic ovary syndrome in adolescents
Published in: International Journal of Pediatric Endocrinology | Special Issue 1/2015
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The diagnosis of polycystic ovary syndrome (PCOS) in adolescents is difficult as the pathological criteria used in adults like menstrual irregularities, acne, hirsutism and polycystic ovarian morphology could be normal physiological findings during puberty; in addition the syndrome is heterogeneous and there is limited high quality evidence. [1‐3] Three international conferences have been held reporting different criteria for diagnosis of PCOS in women [Table 1]. [4‐6] The 2011 Australian PCOS evidence-based guideline [1], the 2012 international evidence-based workshop [2] and the 2013 Endocrine Society Clinical Practice Guideline [3] highlight the issues of applying adult criteria to diagnose PCOS in adolescents.
Table 1
Diagnostic criteria for PCOS in women
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PCOS definition
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Clinical (modified Ferriman-Gallway score >8*) or biochemical hyperandrogenemia (elevated total or free testosterone level **)
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Oligomenorrhoea (< 6-9 menstrual cycles per year) or oligo-anovulation
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Polycystic ovaries on ultrasound (>12 follicles in one ovary or volume >10 cc)
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|---|---|---|---|
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NICHD 1990 [4]
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Yes
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Yes
|
|
|
Rotterdam 2003 [5]
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Yes
|
Yes
|
Yes
|
|
2 of 3 criteria
|
|||
|
AE-PCOS 2009 [6]
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Yes
|
Yes
|
Yes
|
|
1 of 2 criteria
|
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