Skip to main content
Top
Published in: Child and Adolescent Psychiatry and Mental Health 1/2013

Open Access 01-12-2013 | Review

Controversies in autism: is a broader model of social disorders needed?

Authors: Michal Hrdlicka, Iva Dudova

Published in: Child and Adolescent Psychiatry and Mental Health | Issue 1/2013

Login to get access

Abstract

This article examines the most significant, contradictory evidence pertaining to autism. The first section of the article includes reports of recovery from autism, data obtained from studies involving oxytocin, early deprivation, autism in preterm children, late-onset autism, and symptom overlap among ASD, social phobias and personality disorders. In the second section of the article, we offer a model that better incorporates current findings and address controversies that continue to surround ASD. We propose an umbrella term “social inhibition disorders” which integrates autism spectrum disorders and social phobias, as well as schizoid, schizotypal, and obsessive-compulsive personality disorders. It would also include “quasi-autism,” which has been found in early deprivation studies, autism in preterm children, and cases of late-onset autism presenting after herpes encephalitis infection. Finally, we discuss suggestions for further research and clinical perspectives.
Appendix
Available only for authorised users
Literature
1.
go back to reference American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR). 2000, Washington, DC: American Psychiatric Association, 4 American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR). 2000, Washington, DC: American Psychiatric Association, 4
2.
go back to reference World Health Organization: International Classification of Diseases. 1992, Geneva: WHO, 10 World Health Organization: International Classification of Diseases. 1992, Geneva: WHO, 10
3.
go back to reference Amaral DG, Dawson G, Geschwind DH: Autism spectrum disorders. 2011, New York: Oxford University PressCrossRef Amaral DG, Dawson G, Geschwind DH: Autism spectrum disorders. 2011, New York: Oxford University PressCrossRef
4.
go back to reference Hollander E, Kolevzon A, Coyle JT: Textbook of autism spectrum disorders. 2011, Arlington, VA: American Psychiatric Publishing Hollander E, Kolevzon A, Coyle JT: Textbook of autism spectrum disorders. 2011, Arlington, VA: American Psychiatric Publishing
5.
go back to reference Volkmar FR, Paul R, Klin A, Cohen D: Handbook of autism and pervasive developmental disorders. 2005, New York: John Wiley & Sons, 3CrossRef Volkmar FR, Paul R, Klin A, Cohen D: Handbook of autism and pervasive developmental disorders. 2005, New York: John Wiley & Sons, 3CrossRef
6.
go back to reference Volkmar FR, Lord C, Klin A, Schultz R, Cook EH: Autism and the pervasive developmental disorders. Lewis´s child and adolescent psychiatry: a comprehensive textbook . Edited by: Martin A, Volkmar FR. 2007, Philadelphia: Lippincott Williams & Wilkins, 384-400. 4 Volkmar FR, Lord C, Klin A, Schultz R, Cook EH: Autism and the pervasive developmental disorders. Lewis´s child and adolescent psychiatry: a comprehensive textbook . Edited by: Martin A, Volkmar FR. 2007, Philadelphia: Lippincott Williams & Wilkins, 384-400. 4
7.
8.
go back to reference Palmen S, van Engeland H: The relationship between autism and schizophrenia: a reappraisal. Brain, mind, and developmental psychopathology in childhood. Edited by: Garralda ME, Raynaud JP. 2012, Lanham, MD: Jason Aronson, 123-144. Palmen S, van Engeland H: The relationship between autism and schizophrenia: a reappraisal. Brain, mind, and developmental psychopathology in childhood. Edited by: Garralda ME, Raynaud JP. 2012, Lanham, MD: Jason Aronson, 123-144.
9.
go back to reference Happe F: Criteria, categories, and continua: autism and related disorders in DSM-5. J Am Acad Child Adolesc Psychiatry. 2011, 50: 540-542. 10.1016/j.jaac.2011.03.015.CrossRefPubMed Happe F: Criteria, categories, and continua: autism and related disorders in DSM-5. J Am Acad Child Adolesc Psychiatry. 2011, 50: 540-542. 10.1016/j.jaac.2011.03.015.CrossRefPubMed
10.
go back to reference Ozonoff S: DSM-5 and autism spectrum disorders – two decades of perspectives from the JCPP. J Child Psychol Psychiatry. 2012, 10.1111/j.1469-7610.2012.02587.x. Ozonoff S: DSM-5 and autism spectrum disorders – two decades of perspectives from the JCPP. J Child Psychol Psychiatry. 2012, 10.1111/j.1469-7610.2012.02587.x.
12.
go back to reference Hughes JR: Update on autism: a review of 1300 reports published in 2008. Epilepsy Behav. 2009, 16: 569-589. 10.1016/j.yebeh.2009.09.023.CrossRefPubMed Hughes JR: Update on autism: a review of 1300 reports published in 2008. Epilepsy Behav. 2009, 16: 569-589. 10.1016/j.yebeh.2009.09.023.CrossRefPubMed
13.
go back to reference Helt M, Kelley E, Kinsbourne M, Pandey J, Boorstein H, Herbert M, Fein D: Can children with autism recover? If so, how?. Neuropsychol Rev. 2008, 18: 339-366. 10.1007/s11065-008-9075-9.CrossRefPubMed Helt M, Kelley E, Kinsbourne M, Pandey J, Boorstein H, Herbert M, Fein D: Can children with autism recover? If so, how?. Neuropsychol Rev. 2008, 18: 339-366. 10.1007/s11065-008-9075-9.CrossRefPubMed
14.
go back to reference Kamio Y, Tobimatsu S, Fukui H: Developmental disorders. The Oxford handbook of social neuroscience. Edited by: Decety J, Cacioppo JT. 2011, New York: Oxford University Press, 848-858. Kamio Y, Tobimatsu S, Fukui H: Developmental disorders. The Oxford handbook of social neuroscience. Edited by: Decety J, Cacioppo JT. 2011, New York: Oxford University Press, 848-858.
15.
go back to reference Lord C, Risi S, Lambrecht L, Cook EH, Leventhal BL, DiLavore PC, Pickles A, Rutter M: The autism diagnostic observation schedule-generic: a standard measure of social and communication deficits associated with the spectrum of autism. J Autism Dev Disord. 2000, 30: 205-223. 10.1023/A:1005592401947.CrossRefPubMed Lord C, Risi S, Lambrecht L, Cook EH, Leventhal BL, DiLavore PC, Pickles A, Rutter M: The autism diagnostic observation schedule-generic: a standard measure of social and communication deficits associated with the spectrum of autism. J Autism Dev Disord. 2000, 30: 205-223. 10.1023/A:1005592401947.CrossRefPubMed
16.
go back to reference Rutter M: Autistic children: infancy to adulthood. Semin Psychiatry. 1970, 2: 435-450.PubMed Rutter M: Autistic children: infancy to adulthood. Semin Psychiatry. 1970, 2: 435-450.PubMed
17.
go back to reference Lovaas IO: Behavioral treatment and normal educational and intellectual functioning in young autistic children. J Consult Clin Psychol. 1987, 55: 3-9.CrossRefPubMed Lovaas IO: Behavioral treatment and normal educational and intellectual functioning in young autistic children. J Consult Clin Psychol. 1987, 55: 3-9.CrossRefPubMed
18.
go back to reference Sigman M, Ruskin E: Continuity and change in the social competence of children with autism, Down syndrome, and developmental delays. Monogr Soc Res Child Dev. 1999, 64 (1): 1-114. 10.1111/1540-5834.00002.CrossRefPubMed Sigman M, Ruskin E: Continuity and change in the social competence of children with autism, Down syndrome, and developmental delays. Monogr Soc Res Child Dev. 1999, 64 (1): 1-114. 10.1111/1540-5834.00002.CrossRefPubMed
19.
go back to reference Seltzer MM, Krauss MW, Shattuck PT, Orsmond G, Swe A, Lord C: The symptoms of autism spectrum disorders in adolescence and adulthood. J Autism Dev Disord. 2003, 33: 565-581.CrossRefPubMed Seltzer MM, Krauss MW, Shattuck PT, Orsmond G, Swe A, Lord C: The symptoms of autism spectrum disorders in adolescence and adulthood. J Autism Dev Disord. 2003, 33: 565-581.CrossRefPubMed
20.
go back to reference Lord C, Rutter M, LeCouteur A: Autism diagnostic interview - revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord. 1994, 24: 659-685. 10.1007/BF02172145.CrossRefPubMed Lord C, Rutter M, LeCouteur A: Autism diagnostic interview - revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord. 1994, 24: 659-685. 10.1007/BF02172145.CrossRefPubMed
21.
go back to reference Zappella M: Autistic regression with and without EEG abnormalities followed by favourable outcome. Brain Dev. 2010, 32: 739-745. 10.1016/j.braindev.2010.05.004.CrossRefPubMed Zappella M: Autistic regression with and without EEG abnormalities followed by favourable outcome. Brain Dev. 2010, 32: 739-745. 10.1016/j.braindev.2010.05.004.CrossRefPubMed
22.
go back to reference Pellicano E: Do autistic symptoms persist across time? Evidence of substantial change in symptomatology over a 3-year period in cognitively able children with autism. Am J Intellect Dev Disabil. 2012, 117: 156-166. 10.1352/1944-7558-117.2.156.CrossRefPubMed Pellicano E: Do autistic symptoms persist across time? Evidence of substantial change in symptomatology over a 3-year period in cognitively able children with autism. Am J Intellect Dev Disabil. 2012, 117: 156-166. 10.1352/1944-7558-117.2.156.CrossRefPubMed
23.
go back to reference Fountain C, Winter AS, Bearman PS: Six developmental trajectories characterize children with autism. Pediatrics. 2012, 129: e1112-e1120. 10.1542/peds.2011-1601.PubMedCentralCrossRefPubMed Fountain C, Winter AS, Bearman PS: Six developmental trajectories characterize children with autism. Pediatrics. 2012, 129: e1112-e1120. 10.1542/peds.2011-1601.PubMedCentralCrossRefPubMed
24.
go back to reference Miller G: The promise and perils of oxytocin. Science. 2013, 339: 267-269. 10.1126/science.339.6117.267.CrossRefPubMed Miller G: The promise and perils of oxytocin. Science. 2013, 339: 267-269. 10.1126/science.339.6117.267.CrossRefPubMed
25.
go back to reference Hollander E, Novotny S, Hanratty M, Yaffe R, DeCaria C, Aronowitz BR, Mosovich S: Oxytocin infusion reduces repetitive behaviors in adults with autistic and Asperger´s disorders. Neuropsychopharmacology. 2003, 28: 193-198. 10.1038/sj.npp.1300021.CrossRefPubMed Hollander E, Novotny S, Hanratty M, Yaffe R, DeCaria C, Aronowitz BR, Mosovich S: Oxytocin infusion reduces repetitive behaviors in adults with autistic and Asperger´s disorders. Neuropsychopharmacology. 2003, 28: 193-198. 10.1038/sj.npp.1300021.CrossRefPubMed
26.
go back to reference Hollander E, Bartz J, Chaplin W, Phillips A, Sumner J, Soorya L, Anagnostou E, Wasserman S: Oxytocin increases retention of social cognition in autism. Biol Psychiatry. 2007, 61: 498-503. 10.1016/j.biopsych.2006.05.030.CrossRefPubMed Hollander E, Bartz J, Chaplin W, Phillips A, Sumner J, Soorya L, Anagnostou E, Wasserman S: Oxytocin increases retention of social cognition in autism. Biol Psychiatry. 2007, 61: 498-503. 10.1016/j.biopsych.2006.05.030.CrossRefPubMed
27.
go back to reference Andari E, Duhamel JR, Zalla T, Herbrecht E, Leboyer M, Sirigu A: Promoting social behavior with oxytocin in high-functioning autism spectrum disorders. Proc Natl Acad Sci USA. 2010, 107: 4389-4394. 10.1073/pnas.0910249107.PubMedCentralCrossRefPubMed Andari E, Duhamel JR, Zalla T, Herbrecht E, Leboyer M, Sirigu A: Promoting social behavior with oxytocin in high-functioning autism spectrum disorders. Proc Natl Acad Sci USA. 2010, 107: 4389-4394. 10.1073/pnas.0910249107.PubMedCentralCrossRefPubMed
28.
go back to reference Guastella A, Einfeld SL, Gray KM, Rinehart N, Tonge BJ, Lambert TJ, Hickie IB: Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders. Biol Psychiatry. 2010, 67: 692-694. 10.1016/j.biopsych.2009.09.020.CrossRefPubMed Guastella A, Einfeld SL, Gray KM, Rinehart N, Tonge BJ, Lambert TJ, Hickie IB: Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders. Biol Psychiatry. 2010, 67: 692-694. 10.1016/j.biopsych.2009.09.020.CrossRefPubMed
29.
go back to reference Anagnostou E, Soorya L, Chaplin W, Bartz J, Halpern D, Wasserman S, Wang AT, Pepa L, Tanel N, Kushki A, Hollander E: Intranasal oxytocin versus placebo in the treatment of adults with autism spectrum disorders: a randomized controlled trial. Mol Autism. 2012, 3: 16-10.1186/2040-2392-3-16.PubMedCentralCrossRefPubMed Anagnostou E, Soorya L, Chaplin W, Bartz J, Halpern D, Wasserman S, Wang AT, Pepa L, Tanel N, Kushki A, Hollander E: Intranasal oxytocin versus placebo in the treatment of adults with autism spectrum disorders: a randomized controlled trial. Mol Autism. 2012, 3: 16-10.1186/2040-2392-3-16.PubMedCentralCrossRefPubMed
30.
go back to reference Rutter M, English and Romanian Adoptees (ERA) study team: Developmental catch-up, and deficit, following adoption after severe global early privation. J Child Psychol Psychiatry. 1998, 39: 465-476. 10.1017/S0021963098002236.CrossRefPubMed Rutter M, English and Romanian Adoptees (ERA) study team: Developmental catch-up, and deficit, following adoption after severe global early privation. J Child Psychol Psychiatry. 1998, 39: 465-476. 10.1017/S0021963098002236.CrossRefPubMed
31.
go back to reference Rutter M, Kreppner J, Croft C, Murin M, Colvert E, Beckett C, Castle J, Sonuga-Barke E: Early adolescent outcomes of institutionally deprived and non-deprived adoptees. III. Quasi-autism. J Child Psychol Psychiatry. 2007, 48: 1200-1207. 10.1111/j.1469-7610.2007.01792.x.CrossRefPubMed Rutter M, Kreppner J, Croft C, Murin M, Colvert E, Beckett C, Castle J, Sonuga-Barke E: Early adolescent outcomes of institutionally deprived and non-deprived adoptees. III. Quasi-autism. J Child Psychol Psychiatry. 2007, 48: 1200-1207. 10.1111/j.1469-7610.2007.01792.x.CrossRefPubMed
32.
go back to reference Hoksbergen R, ter Laak J, Rijk K, van Dijkum C, Stoutjesdijk F: Post-institutional autistic syndrome in Romanian adoptees. J Autism Dev Disord. 2005, 35: 615-623. 10.1007/s10803-005-0005-x.CrossRefPubMed Hoksbergen R, ter Laak J, Rijk K, van Dijkum C, Stoutjesdijk F: Post-institutional autistic syndrome in Romanian adoptees. J Autism Dev Disord. 2005, 35: 615-623. 10.1007/s10803-005-0005-x.CrossRefPubMed
33.
go back to reference Van Berckelaer-Onnes IA, Hoekman J: Handleiding en verantwoording van de Auti-R schaal ten behoove van de onderkenning van vroegkinderlijk autisme. 1991, Lisse: Swets & Zeitlinger Van Berckelaer-Onnes IA, Hoekman J: Handleiding en verantwoording van de Auti-R schaal ten behoove van de onderkenning van vroegkinderlijk autisme. 1991, Lisse: Swets & Zeitlinger
34.
go back to reference Grafodatskaya D, Chung B, Szatmari P, Weksberg R: Autism spectrum disorders and epigenetics. J Am Acad Child Adolesc Psychiatry. 2010, 49: 794-809. 10.1016/j.jaac.2010.05.005.CrossRefPubMed Grafodatskaya D, Chung B, Szatmari P, Weksberg R: Autism spectrum disorders and epigenetics. J Am Acad Child Adolesc Psychiatry. 2010, 49: 794-809. 10.1016/j.jaac.2010.05.005.CrossRefPubMed
35.
go back to reference Hack M, Taylor HG, Schluchter M, Andreias L, Drotar D, Klein N: Behavioral outcomes of extremely low birth weight children at age 8 years. J Dev Behav Pediatr. 2009, 30: 122-130. 10.1097/DBP.0b013e31819e6a16.PubMedCentralCrossRefPubMed Hack M, Taylor HG, Schluchter M, Andreias L, Drotar D, Klein N: Behavioral outcomes of extremely low birth weight children at age 8 years. J Dev Behav Pediatr. 2009, 30: 122-130. 10.1097/DBP.0b013e31819e6a16.PubMedCentralCrossRefPubMed
36.
go back to reference Johnson S, Hollis C, Kochhar P, Hennesy E, Wolke D, Marlow N: Autism spectrum disorders in extremely preterm children. J Pediatr. 2010, 156: 525-531. 10.1016/j.jpeds.2009.10.041.CrossRefPubMed Johnson S, Hollis C, Kochhar P, Hennesy E, Wolke D, Marlow N: Autism spectrum disorders in extremely preterm children. J Pediatr. 2010, 156: 525-531. 10.1016/j.jpeds.2009.10.041.CrossRefPubMed
37.
go back to reference Pinto-Martin JA, Levy SE, Feldman JF, Lorenz JM, Paneth N, Whitaker AH: Prevalence of autism spectrum disorders in adolescents born weighing <2000 grams. Pediatrics. 2011, 128: 883-891. 10.1542/peds.2010-2846.PubMedCentralCrossRefPubMed Pinto-Martin JA, Levy SE, Feldman JF, Lorenz JM, Paneth N, Whitaker AH: Prevalence of autism spectrum disorders in adolescents born weighing <2000 grams. Pediatrics. 2011, 128: 883-891. 10.1542/peds.2010-2846.PubMedCentralCrossRefPubMed
38.
go back to reference Losh M, Esserman D, Anckarsater H, Sullivan PF, Lichtenstein P: Lower birth weight indicates higher risk of autistic traits in discordant twin pairs. Psychol Med. 2012, 42: 1091-1102. 10.1017/S0033291711002339.PubMedCentralCrossRefPubMed Losh M, Esserman D, Anckarsater H, Sullivan PF, Lichtenstein P: Lower birth weight indicates higher risk of autistic traits in discordant twin pairs. Psychol Med. 2012, 42: 1091-1102. 10.1017/S0033291711002339.PubMedCentralCrossRefPubMed
39.
go back to reference Smith GC, Gutovich J, Smyser C, Pineda R, Newnham C, Tjoeng TH, Vavasseur C, Wallendorf M, Neil J, Inder T: Neonatal intensive care unit stress is associated with brain development in preterm infants. Ann Neurol. 2011, 70: 541-549. 10.1002/ana.22545.CrossRefPubMed Smith GC, Gutovich J, Smyser C, Pineda R, Newnham C, Tjoeng TH, Vavasseur C, Wallendorf M, Neil J, Inder T: Neonatal intensive care unit stress is associated with brain development in preterm infants. Ann Neurol. 2011, 70: 541-549. 10.1002/ana.22545.CrossRefPubMed
40.
go back to reference Hrdlicka M: Structural neuroimaging in autism. Neuroendocrinol Lett. 2008, 29: 281-286.PubMed Hrdlicka M: Structural neuroimaging in autism. Neuroendocrinol Lett. 2008, 29: 281-286.PubMed
41.
go back to reference Stanfield AC, McIntosh AM, Spencer MD, Philip R, Gaur S, Lawrie SM, Towards a neuroanatomy of autism: A systematic review and meta-analysis of structural magnetic resonance imaging studies. Eur Psychiatry. 2008, 23: 289-299. 10.1016/j.eurpsy.2007.05.006.CrossRefPubMed Stanfield AC, McIntosh AM, Spencer MD, Philip R, Gaur S, Lawrie SM, Towards a neuroanatomy of autism: A systematic review and meta-analysis of structural magnetic resonance imaging studies. Eur Psychiatry. 2008, 23: 289-299. 10.1016/j.eurpsy.2007.05.006.CrossRefPubMed
42.
go back to reference Malhotra S, Gupta N: Childhood disintegrative disorder. Re-examination of the current concept. Eur Child Adolesc Psychiatry. 2002, 11: 108-114. 10.1007/s00787-002-0270-6.CrossRefPubMed Malhotra S, Gupta N: Childhood disintegrative disorder. Re-examination of the current concept. Eur Child Adolesc Psychiatry. 2002, 11: 108-114. 10.1007/s00787-002-0270-6.CrossRefPubMed
43.
go back to reference DeLong GR, Bean C, Brown FR: Acquired reversible autistic syndrome in acute encephalopathic illness in children. Arch Neurol. 1981, 38: 191-194. 10.1001/archneur.1981.00510030085013.CrossRefPubMed DeLong GR, Bean C, Brown FR: Acquired reversible autistic syndrome in acute encephalopathic illness in children. Arch Neurol. 1981, 38: 191-194. 10.1001/archneur.1981.00510030085013.CrossRefPubMed
44.
go back to reference Ghaziuddin M, Al-Khouri I, Ghaziuddin N: Autistic symptoms following herpes encephalitis. Eur Child Adolesc Psychiatry. 2002, 11: 142-146. 10.1007/s00787-002-0271-5.CrossRefPubMed Ghaziuddin M, Al-Khouri I, Ghaziuddin N: Autistic symptoms following herpes encephalitis. Eur Child Adolesc Psychiatry. 2002, 11: 142-146. 10.1007/s00787-002-0271-5.CrossRefPubMed
45.
go back to reference Gillberg C: Brief report: onset at age 14 of a typical autistic syndrome. A case report of a girl with herpes simplex encephalitis. J Autism Dev Disord. 1986, 16: 369-375. 10.1007/BF01531665.CrossRefPubMed Gillberg C: Brief report: onset at age 14 of a typical autistic syndrome. A case report of a girl with herpes simplex encephalitis. J Autism Dev Disord. 1986, 16: 369-375. 10.1007/BF01531665.CrossRefPubMed
46.
go back to reference Gillberg IC: Autistic syndrome with onset at age 31 years: herpes encephalitis as a possible model for childhood autism. Dev Med Child Neurol. 1991, 33: 912-929. Gillberg IC: Autistic syndrome with onset at age 31 years: herpes encephalitis as a possible model for childhood autism. Dev Med Child Neurol. 1991, 33: 912-929.
47.
go back to reference Popper K: Conjectures and refutations: The growth of scientific knowledge. 1963, London: Routledge Popper K: Conjectures and refutations: The growth of scientific knowledge. 1963, London: Routledge
48.
go back to reference Tyson KE, Cruess DG: Differentiating high-functioning autism and social phobia. J Autism Dev Disord. 2012, 42: 1477-1490. 10.1007/s10803-011-1386-7.CrossRefPubMed Tyson KE, Cruess DG: Differentiating high-functioning autism and social phobia. J Autism Dev Disord. 2012, 42: 1477-1490. 10.1007/s10803-011-1386-7.CrossRefPubMed
49.
go back to reference Van Steensel FJA, Bogels SM, Wood JJ: Autism spectrum traits in children with anxiety disorders. J Autism Dev Disord. 2013, 43: 361-370. 10.1007/s10803-012-1575-z.PubMedCentralCrossRefPubMed Van Steensel FJA, Bogels SM, Wood JJ: Autism spectrum traits in children with anxiety disorders. J Autism Dev Disord. 2013, 43: 361-370. 10.1007/s10803-012-1575-z.PubMedCentralCrossRefPubMed
50.
go back to reference Lugnegard T, Hallerback MU, Gillberg C: Personality disorders and autism spectrum disorders: what are the connections?. Compr Psychiatry. 2012, 53: 333-340. 10.1016/j.comppsych.2011.05.014.CrossRefPubMed Lugnegard T, Hallerback MU, Gillberg C: Personality disorders and autism spectrum disorders: what are the connections?. Compr Psychiatry. 2012, 53: 333-340. 10.1016/j.comppsych.2011.05.014.CrossRefPubMed
51.
go back to reference De Pauw SSW, Mervielde I, Van Leeuwen KG, De Clercq BJ: How temperament and personality contribute to the maladjustment of children with autism. J Autism Dev Disord. 2011, 41: 196-212. 10.1007/s10803-010-1043-6.CrossRefPubMed De Pauw SSW, Mervielde I, Van Leeuwen KG, De Clercq BJ: How temperament and personality contribute to the maladjustment of children with autism. J Autism Dev Disord. 2011, 41: 196-212. 10.1007/s10803-010-1043-6.CrossRefPubMed
52.
go back to reference Hurst RM, Nelson-Gray RO, Mitchell JT, Kwapil TR: The relationship of Asperger’s characteristics and schizotypal personality traits in a non-clinical adult sample. J Autism Dev Disord. 2007, 37: 1711-1720. 10.1007/s10803-006-0302-z.CrossRefPubMed Hurst RM, Nelson-Gray RO, Mitchell JT, Kwapil TR: The relationship of Asperger’s characteristics and schizotypal personality traits in a non-clinical adult sample. J Autism Dev Disord. 2007, 37: 1711-1720. 10.1007/s10803-006-0302-z.CrossRefPubMed
53.
go back to reference Barneveld P, Pieterse J, de Sonneville L, van Rijn S, Lahuis B, van Engeland H, Schwab H: Overlap of autistic and schizotypal traits in adolescents with autism spectrum disorders. Schizophr Res. 2011, 126: 231-236. 10.1016/j.schres.2010.09.004.CrossRefPubMed Barneveld P, Pieterse J, de Sonneville L, van Rijn S, Lahuis B, van Engeland H, Schwab H: Overlap of autistic and schizotypal traits in adolescents with autism spectrum disorders. Schizophr Res. 2011, 126: 231-236. 10.1016/j.schres.2010.09.004.CrossRefPubMed
54.
go back to reference Dawson G: Early behavioral intervention, brain plasticity, and prevention of autism spectrum disorder. Dev Psychopathol. 2008, 20: 775-803.CrossRefPubMed Dawson G: Early behavioral intervention, brain plasticity, and prevention of autism spectrum disorder. Dev Psychopathol. 2008, 20: 775-803.CrossRefPubMed
55.
go back to reference Schultz RT: Developmental deficits in social perception in autism: the role of amygdala and fusiform face area. Int J Dev Neurosci. 2005, 23: 125-141. 10.1016/j.ijdevneu.2004.12.012.CrossRefPubMed Schultz RT: Developmental deficits in social perception in autism: the role of amygdala and fusiform face area. Int J Dev Neurosci. 2005, 23: 125-141. 10.1016/j.ijdevneu.2004.12.012.CrossRefPubMed
56.
go back to reference Ozonoff S, Williams BJ, Landa R: Parental reports of the early development of children with regressive autism: the delays-plus-regression phenotype. Autism. 2005, 9: 461-486. 10.1177/1362361305057880.CrossRefPubMed Ozonoff S, Williams BJ, Landa R: Parental reports of the early development of children with regressive autism: the delays-plus-regression phenotype. Autism. 2005, 9: 461-486. 10.1177/1362361305057880.CrossRefPubMed
57.
go back to reference Constantino JN, Todd RD: Autistic traits in the general population. Arch Gen Psychiatry. 2003, 60: 524-530. 10.1001/archpsyc.60.5.524.CrossRefPubMed Constantino JN, Todd RD: Autistic traits in the general population. Arch Gen Psychiatry. 2003, 60: 524-530. 10.1001/archpsyc.60.5.524.CrossRefPubMed
58.
go back to reference Constantino JN, Gruber CP, Davis S, Hayes S, Passanante N, Przybeck T: The factor structure of autistic traits. J Child Psychol Psychiatry. 2004, 45: 719-726. 10.1111/j.1469-7610.2004.00266.x.CrossRefPubMed Constantino JN, Gruber CP, Davis S, Hayes S, Passanante N, Przybeck T: The factor structure of autistic traits. J Child Psychol Psychiatry. 2004, 45: 719-726. 10.1111/j.1469-7610.2004.00266.x.CrossRefPubMed
59.
go back to reference Constantino JN, LaJonchere C, Lutz M, Gray T, Abbacchi A, McKenna K, Singh D, Todd RD: Autistic social impairment in the siblings of children with pervasive developmental disorders. Am J Psychiatry. 2006, 163: 294-296. 10.1176/appi.ajp.163.2.294.CrossRefPubMed Constantino JN, LaJonchere C, Lutz M, Gray T, Abbacchi A, McKenna K, Singh D, Todd RD: Autistic social impairment in the siblings of children with pervasive developmental disorders. Am J Psychiatry. 2006, 163: 294-296. 10.1176/appi.ajp.163.2.294.CrossRefPubMed
60.
go back to reference Robinson EB, Koenen KC, McCormick MC, Munir K, Hallett V, Happe F, Plomin R, Ronald A: Evidence that autistic traits show the same etiology in the general population and at the quantitative extremes (5%, 2.5%, and 1%). Arch Gen Psychiatry. 2011, 68: 1113-1121. 10.1001/archgenpsychiatry.2011.119.PubMedCentralCrossRefPubMed Robinson EB, Koenen KC, McCormick MC, Munir K, Hallett V, Happe F, Plomin R, Ronald A: Evidence that autistic traits show the same etiology in the general population and at the quantitative extremes (5%, 2.5%, and 1%). Arch Gen Psychiatry. 2011, 68: 1113-1121. 10.1001/archgenpsychiatry.2011.119.PubMedCentralCrossRefPubMed
61.
go back to reference Hallett V, Ronald A, Rijsdijk F, Happe F: Association of autistic-like and internalizing traits during childhood: a longitudinal twin study. Am J Psychiatry. 2010, 167: 809-817. 10.1176/appi.ajp.2009.09070990.CrossRefPubMed Hallett V, Ronald A, Rijsdijk F, Happe F: Association of autistic-like and internalizing traits during childhood: a longitudinal twin study. Am J Psychiatry. 2010, 167: 809-817. 10.1176/appi.ajp.2009.09070990.CrossRefPubMed
62.
go back to reference Newschaffer CJ, Fallin D, Lee NL: Heritable and nonheritable risk factors for autism spectrum disorders. Epidemiol Rev. 2002, 24: 137-153. 10.1093/epirev/mxf010.CrossRefPubMed Newschaffer CJ, Fallin D, Lee NL: Heritable and nonheritable risk factors for autism spectrum disorders. Epidemiol Rev. 2002, 24: 137-153. 10.1093/epirev/mxf010.CrossRefPubMed
63.
go back to reference Happe F, Ronald A, Plomin R: Time to give up on a single explanation for autism. Nat Neurosci. 2006, 9: 1218-1220. 10.1038/nn1770.CrossRefPubMed Happe F, Ronald A, Plomin R: Time to give up on a single explanation for autism. Nat Neurosci. 2006, 9: 1218-1220. 10.1038/nn1770.CrossRefPubMed
Metadata
Title
Controversies in autism: is a broader model of social disorders needed?
Authors
Michal Hrdlicka
Iva Dudova
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Child and Adolescent Psychiatry and Mental Health / Issue 1/2013
Electronic ISSN: 1753-2000
DOI
https://doi.org/10.1186/1753-2000-7-9

Other articles of this Issue 1/2013

Child and Adolescent Psychiatry and Mental Health 1/2013 Go to the issue