Published in:
01-05-2013 | Ultrasound
Contrast-enhanced ultrasound (CEUS) follow-up after radiofrequency ablation or cryoablation of focal liver lesions: treated-area patterns and their changes over time
Authors:
Aymeric Guibal, Caroline Bertin, Sophie Egels, Eric Savier, Philippe A. Grenier, Olivier Lucidarme
Published in:
European Radiology
|
Issue 5/2013
Login to get access
Abstract
Objectives
To describe the early patterns of liver lesions successfully treated with radiofrequency ablation (RFA) or cryoablation (CA) and their changes over time.
Methods
Twenty-two RFA-treated and 17 CA-treated patients underwent CEUS from week 1 to year 3 post-ablation. Patterns, margins and volumes of RF-induced and cryolesions were evaluated and compared over time.
Results
After contrast enhancement, shortly after ablation, undefined margins with persistent enhancing small vessels penetrating >2 mm into the treated zone were significantly more frequent after CA (67 %) than RFA (22 %) (P < 0.02). During the arterial phase, a thin, enhancing marginal rim was seen during week 1 (T1) in around 28 % of RF lesions, while 75 % of cryolesions had thick enhancing rims (P < 0.02). The mean RF-induced lesion volume, maximum at T1 (44.1 ± 37.5 ml), shrank slowly over time, remaining clearly visible at 1 year (8.3 ± 7.4 ml). Cryolesions shrank faster (P = 0.009), from an average of 16.6 ± 7.1 ml at T1 to 1.7 ± 1.3 ml 1-year post-ablation.
Conclusion
RF-induced and cryolesions differ, particularly their margins and shrinkage rates. Knowing these differences allows avoidance of incomplete treatment or falsely diagnosed recurrence, especially after CA.
Key Points
• Contrast-enhanced ultrasound (CEUS) provides new follow-up information following hepatic radiological inyervention.
• CEUS provides good visualisation of vascular modifications after thermoablation.
• RFA-induced lesions and cryoablated lesions differ.
• Knowledge about RF and cryolesion patterns is essential for correct CEUS follow-up.
• Cryolesions have thicker peripheral inflammatory reactions and shrink faster than RFA-induced lesions.