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Published in: Pediatric Nephrology 3/2006

01-03-2006 | Original Article

Continuous peritoneal dialysis in children: a single-centre experience in a developing country

Authors: Narayan Prasad, Sanjeev Gulati, Amit Gupta, Raj Kumar Sharma, Alok Kumar, Ramesh Kumar, Dhulipala V. S. Julu

Published in: Pediatric Nephrology | Issue 3/2006

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Abstract

Continuous peritoneal dialysis (CPD) is the most commonly used modality of dialysis in children. Continuous ambulatory peritoneal dialysis (CAPD) has been an established form of therapy in adult patients with end-stage renal failure in India for more than a decade. There is a paucity of published experience of CPD in children from developing countries. We retrospectively studied children with end-stage renal failure (ESRD) that had been on CAPD over the past 10 years. Thirty patients with ESRD, mean age 13±8 years (range 5–21 years), male 18, were started on CAPD from 1994 to October 2004. The mean break-in period was 12±3 days. Of these 30 patients, 15 had a total of 21 episodes of peritonitis. The peritonitis rate was 0.58 episodes per patient year. E. coli was the commonest organism causing peritonitis. On outcome analysis, 7/30 (23.3%) patients received a renal transplant, while 11/30 (36.6%) continued on CAPD, awaiting a kidney transplant. Of the rest, eight (26.6%) patients died, two (6.7%) suffered technique failure and were changed to haemodialysis, and two (6.7%) were lost to follow-up after 2 months. The mean cumulative survival time of patient on CPD was 42 months. We conclude that CPD is a viable option for dialysis in ESRD children in a developing country and is a successful bridge between ESRD and renal transplantation
Literature
1.
go back to reference Warady BA, Hebert D, Sullian EK, Alexander SR, Tajan A (1997) Renal transplantation, chronic dialysis and chronic renal insufficiency in children and adolescents. The 1995 Annual Report of the North American Pediatric Renal Transplant Cooperative Study. Pediatr Nephrol 11:49–64CrossRefPubMed Warady BA, Hebert D, Sullian EK, Alexander SR, Tajan A (1997) Renal transplantation, chronic dialysis and chronic renal insufficiency in children and adolescents. The 1995 Annual Report of the North American Pediatric Renal Transplant Cooperative Study. Pediatr Nephrol 11:49–64CrossRefPubMed
2.
go back to reference Alexander SR, Donaldson LA, Sullivan EK (1998) CAPD/CCPD for children in North America: The NAPRTCS experience. In: Fine RN, Alexander SR, Warady BA (eds) CAPD/CCPD in children, 2nd edn. Kluwer, Boston, pp 1–16 Alexander SR, Donaldson LA, Sullivan EK (1998) CAPD/CCPD for children in North America: The NAPRTCS experience. In: Fine RN, Alexander SR, Warady BA (eds) CAPD/CCPD in children, 2nd edn. Kluwer, Boston, pp 1–16
3.
go back to reference Alexander SR, Salusky IB, Warady BA, Watkins SL (1997) Peritoneal dialysis workshop: Pediatric recommendations. Perit Dial Int 17 [Suppl 3]:S25–S27 Alexander SR, Salusky IB, Warady BA, Watkins SL (1997) Peritoneal dialysis workshop: Pediatric recommendations. Perit Dial Int 17 [Suppl 3]:S25–S27
4.
go back to reference Salusky IB, Holloway M (1997) Selection of peritoneal dialysis for pediatric patients. Perit Dial Int 17 [Suppl 3]:S35–S37 Salusky IB, Holloway M (1997) Selection of peritoneal dialysis for pediatric patients. Perit Dial Int 17 [Suppl 3]:S35–S37
5.
go back to reference Lingens N, Soergel M, Loiret C, Busch C, Lemmer B, Scharer K (1995) Ambulatory blood pressure monitoring in pediatric patients treated by regular hemodialysis and peritoneal dialysis. Pediatr Nephrol 9:167–172CrossRefPubMed Lingens N, Soergel M, Loiret C, Busch C, Lemmer B, Scharer K (1995) Ambulatory blood pressure monitoring in pediatric patients treated by regular hemodialysis and peritoneal dialysis. Pediatr Nephrol 9:167–172CrossRefPubMed
6.
go back to reference Kaiser BA, Polinsky MS, Stover J, Morgenstern BZ, Baluarte HJ (1994) Growth of children following the initiation of dialysis: a comparison of three modalities. Pediatr Nephrol 8:733–738CrossRefPubMed Kaiser BA, Polinsky MS, Stover J, Morgenstern BZ, Baluarte HJ (1994) Growth of children following the initiation of dialysis: a comparison of three modalities. Pediatr Nephrol 8:733–738CrossRefPubMed
7.
go back to reference Prasad N, Gupta A, Sharma RK, Prasad KN, Gulati S, Sharma AP (2003) Outcome of gram positive and gram negative peritonitis in patients on continuous ambulatory peritoneal dialysis: a single-center experience. Perit Dial Int 23 [Suppl 2]:S144–S147 Prasad N, Gupta A, Sharma RK, Prasad KN, Gulati S, Sharma AP (2003) Outcome of gram positive and gram negative peritonitis in patients on continuous ambulatory peritoneal dialysis: a single-center experience. Perit Dial Int 23 [Suppl 2]:S144–S147
8.
go back to reference Oreopolus DG, Vas SI (1987) Peritonitis in continuous ambulatory peritoneal dialysis: making therapeutic decision easier. Arch Int Med 147:818–819CrossRef Oreopolus DG, Vas SI (1987) Peritonitis in continuous ambulatory peritoneal dialysis: making therapeutic decision easier. Arch Int Med 147:818–819CrossRef
9.
go back to reference North American Pediatric Renal Transplant Cooperative Study (1997) Annual Data Report. EMMES Corporation, Potomac, MD, p 75 North American Pediatric Renal Transplant Cooperative Study (1997) Annual Data Report. EMMES Corporation, Potomac, MD, p 75
10.
go back to reference Khoury AE, Charendoff J, Balfe JW, McLorie GA, Churchill BM (1991) Hernias associated with CAPD in children. Adv Perit Dial 7:279–282PubMed Khoury AE, Charendoff J, Balfe JW, McLorie GA, Churchill BM (1991) Hernias associated with CAPD in children. Adv Perit Dial 7:279–282PubMed
11.
go back to reference Von Lilien T, Salusky IB, Yap HK, Fonkalsrud EW, Fine RN (1987) Hernias, a frequent complication in children treated with continuous peritoneal dialysis. Am J Kidney Dis 10:356–360PubMed Von Lilien T, Salusky IB, Yap HK, Fonkalsrud EW, Fine RN (1987) Hernias, a frequent complication in children treated with continuous peritoneal dialysis. Am J Kidney Dis 10:356–360PubMed
12.
go back to reference Warady BA, Sullivan EK, Alexander SR (1996) Lesson from the pediatric dialysis patient database: a report of the North American Pediatric Renal Transplant Cooperative study. Kidney Int 49 [Suppl 53] S68–S71 Warady BA, Sullivan EK, Alexander SR (1996) Lesson from the pediatric dialysis patient database: a report of the North American Pediatric Renal Transplant Cooperative study. Kidney Int 49 [Suppl 53] S68–S71
13.
go back to reference Port FK, Held PJ, Nolph KD, Turenne MN, Wolfe RA (1992) Risk of peritonitis and technique failure by CAPD connection technique: a national study. Kidney Int 42:967–974PubMed Port FK, Held PJ, Nolph KD, Turenne MN, Wolfe RA (1992) Risk of peritonitis and technique failure by CAPD connection technique: a national study. Kidney Int 42:967–974PubMed
14.
go back to reference Warady BA, Campoy SF, Gross SP, Sedman AB, Lum GM (1984) Peritonitis with continuous ambulatory peritoneal dialysis and continuous cycling peritoneal dialysis. J Pediatr 105:726–730PubMed Warady BA, Campoy SF, Gross SP, Sedman AB, Lum GM (1984) Peritonitis with continuous ambulatory peritoneal dialysis and continuous cycling peritoneal dialysis. J Pediatr 105:726–730PubMed
15.
go back to reference Levy M, Balfe JW (1994) Optimal approach to the prevention and treatment of peritonitis in children undergoing continuous ambulatory and continuous cycling peritoneal dialysis. Semin Dial 7:442–449 Levy M, Balfe JW (1994) Optimal approach to the prevention and treatment of peritonitis in children undergoing continuous ambulatory and continuous cycling peritoneal dialysis. Semin Dial 7:442–449
16.
go back to reference Kingwatanakul P, Warady BA (1997) Staphylococcus nasal carriage in children receiving long-term peritoneal dialysis. Adv Perit Dial 13:280–283 Kingwatanakul P, Warady BA (1997) Staphylococcus nasal carriage in children receiving long-term peritoneal dialysis. Adv Perit Dial 13:280–283
17.
go back to reference Gulati S, Stephens D, Balfe JA, Secker D, Harvey E, Balfe JW (2001) Children with hypoalbuminemia on continuous peritoneal dialysis are at risk for technique failure. Kidney Int 59:2361–2366PubMed Gulati S, Stephens D, Balfe JA, Secker D, Harvey E, Balfe JW (2001) Children with hypoalbuminemia on continuous peritoneal dialysis are at risk for technique failure. Kidney Int 59:2361–2366PubMed
18.
go back to reference Young GA, Young JB, Young SM, Hobson SM, Hildreth B, Brownjohn AM, Parsons FM (1986) Nutrition and delayed hypersensitivity during continuous ambulatory peritoneal dialysis in relation to peritonitis. Nephron 43:177–186PubMed Young GA, Young JB, Young SM, Hobson SM, Hildreth B, Brownjohn AM, Parsons FM (1986) Nutrition and delayed hypersensitivity during continuous ambulatory peritoneal dialysis in relation to peritonitis. Nephron 43:177–186PubMed
19.
go back to reference Fine RN, Ho M, North American Pediatric Renal Transplant Cooperative Study (2002) The role of APD in the management of pediatric patients: a report of the North American Pediatric Renal Transplant Cooperative Study. Semin Dial 15:427–429CrossRefPubMed Fine RN, Ho M, North American Pediatric Renal Transplant Cooperative Study (2002) The role of APD in the management of pediatric patients: a report of the North American Pediatric Renal Transplant Cooperative Study. Semin Dial 15:427–429CrossRefPubMed
20.
go back to reference Donmez O, Aladag S, Cigerdelen N, Kocak S (2003) Outcome in children on chronic peritoneal dialysis. Adv Perit Dial 19:269–272PubMed Donmez O, Aladag S, Cigerdelen N, Kocak S (2003) Outcome in children on chronic peritoneal dialysis. Adv Perit Dial 19:269–272PubMed
21.
go back to reference Romao Junior JE, Fares JA, Silva EC, Fadil MA, Abensur H, Massola VC, Marcondes M, Sabbaga E (1989) Continuous ambulatory peritoneal dialysis: efficient treatment for children with terminal uremia. Rev Assoc Med Bras 35:103–106 Romao Junior JE, Fares JA, Silva EC, Fadil MA, Abensur H, Massola VC, Marcondes M, Sabbaga E (1989) Continuous ambulatory peritoneal dialysis: efficient treatment for children with terminal uremia. Rev Assoc Med Bras 35:103–106
22.
go back to reference Luque-Coqui M, Chartt R, Tercero G, Hernandez Roque A, Romero B, Morales F (2003) Self-esteem in Mexican pediatric patients on peritoneal dialysis and kidney transplantation. Nefrologia.23:145–149 Luque-Coqui M, Chartt R, Tercero G, Hernandez Roque A, Romero B, Morales F (2003) Self-esteem in Mexican pediatric patients on peritoneal dialysis and kidney transplantation. Nefrologia.23:145–149
Metadata
Title
Continuous peritoneal dialysis in children: a single-centre experience in a developing country
Authors
Narayan Prasad
Sanjeev Gulati
Amit Gupta
Raj Kumar Sharma
Alok Kumar
Ramesh Kumar
Dhulipala V. S. Julu
Publication date
01-03-2006
Publisher
Springer-Verlag
Published in
Pediatric Nephrology / Issue 3/2006
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-005-2090-7

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