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Clinical Oral Investigations
Published in: Clinical Oral Investigations 1/2014

01-01-2014 | Original Article

Contact allergies to potential allergens in patients with oral lichen lesions

Authors: Camilla Ahlgren, Tony Axéll, Halvor Möller, Marléne Isaksson, Rolf Liedholm, Magnus Bruze

Published in: Clinical Oral Investigations | Issue 1/2014

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Abstract

Objective

The aim of the present controlled study was to investigate a possible relationship between contact allergies to potential allergens and oral lichen lesions.

Methods

Eighty-three patients with oral lichen lesions (OLL) and control groups of age- and gender-matched dermatitis patients (DP, n = 83) and patch-tested dermatitis patients randomly selected from files (PSFF, n = 319) were included in the study. OLL and DP groups were patch-tested epicutaneously and examined intraorally.

Results

The frequencies of contact allergy to mercury and carvone were statistically higher in the OLL group than in the DP group. Surfaces of amalgam and composite restorations were statistically more frequent in the OLL group compared to the DP group. Contact allergy to nickel and colophony, the latter with a statistically significant difference, was more common in the DP group. The numerical difference found for nickel allergy was, however, not significant comparing the OLL and PSFF groups.

Conclusion

Contact allergy to mercury was overrepresented in patients with OLL and has been reported in previous studies, but the present finding of an overrepresentation of contact allergy to carvone in patients with oral lichen lesions has not been reported previously.

Clinical relevance

Carvone, in addition to mercury and gold, as previously suggested, can be one of the causative or maintenant factors for oral lichen lesions. Carvone-hypersensitive patients with oral lichen lesions should therefore avoid carvone-containing products for oral use.
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Metadata
Title
Contact allergies to potential allergens in patients with oral lichen lesions
Authors
Camilla Ahlgren
Tony Axéll
Halvor Möller
Marléne Isaksson
Rolf Liedholm
Magnus Bruze
Publication date
01-01-2014
Publisher
Springer Berlin Heidelberg
Published in
Clinical Oral Investigations / Issue 1/2014
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-013-0950-2

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