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Cancer Causes & Control
Published in: Cancer Causes & Control 4/2013

01-04-2013 | Original paper

Consumption of dairy and meat in relation to breast cancer risk in the Black Women’s Health Study

Authors: Jeanine M. Genkinger, Kepher H. Makambi, Julie R. Palmer, Lynn Rosenberg, Lucile L. Adams-Campbell

Published in: Cancer Causes & Control | Issue 4/2013

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Abstract

Purpose

Dairy and meat consumption may impact breast cancer risk through modification of hormones (e.g., estrogen), through specific nutrients (e.g., vitamin D), or through products formed in processing/cooking (e.g., heterocyclic amines). Results relating meat and dairy intake to breast cancer risk have been conflicting. Thus, we examined the risk of breast cancer in relation to intake of dairy and meat in a large prospective cohort study.

Methods

In the Black Women’s Health Study, 1,268 incident breast cancer cases were identified among 52,062 women during 12 years of follow-up. Multivariable (MV) relative risks (RRs) and 95 % confidence intervals (CIs) were calculated using Cox proportional hazards models.

Results

Null associations were observed for total milk (MV RR = 1.05, 95 % CI 0.74–1.46 comparing ≥1,000–0 g/week) and total meat (MV RR = 1.04, 95 % CI 0.85–1.28 comparing ≥1,000 < 400 g/week) intake and risk of breast cancer. Associations with intakes of specific types of dairy, specific types of meat, and dietary calcium and vitamin D were also null. The associations were not modified by reproductive (e.g., parity) or lifestyle factors (e.g., smoking). Associations with estrogen receptor (ER) positive (+), ER negative (−), progesterone receptor (PR) +, PR−, ER+/PR+, and ER−/PR− breast cancer were generally null.

Conclusions

This analysis of African-American women provides little support for associations of dairy and meat intake with breast cancer risk.
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Metadata
Title
Consumption of dairy and meat in relation to breast cancer risk in the Black Women’s Health Study
Authors
Jeanine M. Genkinger
Kepher H. Makambi
Julie R. Palmer
Lynn Rosenberg
Lucile L. Adams-Campbell
Publication date
01-04-2013
Publisher
Springer Netherlands
Published in
Cancer Causes & Control / Issue 4/2013
Print ISSN: 0957-5243
Electronic ISSN: 1573-7225
DOI
https://doi.org/10.1007/s10552-013-0146-8

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