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Published in: BMC Gastroenterology 1/2020

Open Access 01-12-2020 | Constipation | Research article

Impact of guideline awareness in public pharmacies on counseling of patients with acute or chronic constipation in a survey of pharmacy personnel

Authors: Marion Eberlin, Sabine Landes, Doerthe Biber-Feiter, Martin C. Michel

Published in: BMC Gastroenterology | Issue 1/2020

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Abstract

Background

Constipation is often self-managed by patients and guidelines are available to aid healthcare professionals in the counseling of patients for self-management. Therefore, we have explored the knowledge and attitude of pharmacy personnel towards guidelines for the management of acute and functional chronic constipation and how they affects their recommendations.

Methods

An online survey was conducted among 201 pharmacists and pharmacy technicians from an existing panel. They were presented with two typical cases, a 62-year old woman with functional chronic constipation and a 42-year old woman with travel plans. For each case, they were asked about their treatment recommendations and the underlying rationale. Thereafter, they were provided with contents from an applicable national guideline and asked again about their recommendations and the underlying rationale. In line with the exploratory nature, data were analyzed in a descriptive manner only.

Results

Before exposure to guideline content, the most frequent recommendations for chronic constipation were macrogol, fiber and lactulose and for acute constipation sodium picosulfate, bisacodyl and enemas. Following guideline exposure, the most frequent recommendations for chronic constipation were macrogol, bisacodyl and sodium picosulfate and for acute constipation bisacodyl, sodium picosulfate and macrogol (all three equally recommended by the guideline for the management of acute and chronic constipation). Correspondingly, the rationale behind the recommendations shifted with guideline conformity becoming a leading reason.

Conclusions

Awareness of the content of an applicable guideline on the management of constipation was poor among pharmacy personnel. Accordingly, recommendations in many cases were not in line with the guideline. Greater awareness of guideline content is desirable to enable more evidence-based recommendations in the management of constipation.
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Literature
1.
go back to reference Mearin F, Ciriza C, Mínguez M, Rey E, Mascort JJ, Peña E, et al. Clinical practice guideline: irritable bowel syndrome with constipation and functional constipation in the adult. Rev Esp Enferm Dig. 2016;108(6):332–63.PubMed Mearin F, Ciriza C, Mínguez M, Rey E, Mascort JJ, Peña E, et al. Clinical practice guideline: irritable bowel syndrome with constipation and functional constipation in the adult. Rev Esp Enferm Dig. 2016;108(6):332–63.PubMed
2.
go back to reference McCrea GL, Miaskowski C, Stotts NA, Macera L, Varma MG. A review of the literature on gender and age differences in the prevalence and characteristics of constipation in North America. J Pain Symptom Manag. 2009;37(4):737–45.CrossRef McCrea GL, Miaskowski C, Stotts NA, Macera L, Varma MG. A review of the literature on gender and age differences in the prevalence and characteristics of constipation in North America. J Pain Symptom Manag. 2009;37(4):737–45.CrossRef
3.
go back to reference Andresen V, Enck P, Frieling T, Herold A, Ilgenstein P, Jesse N, et al. S2k-Leitlinie chronische obstipation: definition, pathophysiologie, diagnostik und therapie. Z Gastroenterol. 2011;51:651–72. Andresen V, Enck P, Frieling T, Herold A, Ilgenstein P, Jesse N, et al. S2k-Leitlinie chronische obstipation: definition, pathophysiologie, diagnostik und therapie. Z Gastroenterol. 2011;51:651–72.
4.
go back to reference Johanson JF, Kralstein J. Chronic constipation: a survey of the patient perspective. Aliment Pharmacol Ther. 2007;25(5):599–608.CrossRef Johanson JF, Kralstein J. Chronic constipation: a survey of the patient perspective. Aliment Pharmacol Ther. 2007;25(5):599–608.CrossRef
5.
go back to reference Pare P, Ferrazzi S, Thompson WG, Irvine EJ, Rance L. An epidemiological survey of constipation in Canada: definitions, rates, demographics, and predictors of health care seeking. Am J Gastroenterol. 2001;96:3130.CrossRef Pare P, Ferrazzi S, Thompson WG, Irvine EJ, Rance L. An epidemiological survey of constipation in Canada: definitions, rates, demographics, and predictors of health care seeking. Am J Gastroenterol. 2001;96:3130.CrossRef
6.
go back to reference Enck P, Leinert J, Smid M, Köhler T, Schwille-Kiuntke J. Prevalence of constipation in the German population – a representative survey (GECCO). United European Gastroenterol J. 2016;4(3):429–37.CrossRef Enck P, Leinert J, Smid M, Köhler T, Schwille-Kiuntke J. Prevalence of constipation in the German population – a representative survey (GECCO). United European Gastroenterol J. 2016;4(3):429–37.CrossRef
7.
go back to reference Bharucha AE, Dorn SD, Lembo A, Pressman A. American Gastroenterological Association medical position statement on constipation. Gastroenterology. 2013;144(1):211–7.CrossRef Bharucha AE, Dorn SD, Lembo A, Pressman A. American Gastroenterological Association medical position statement on constipation. Gastroenterology. 2013;144(1):211–7.CrossRef
8.
go back to reference Belsey J, Greenfield S, Candy D, Geraint M. Systematic review: impact of constipation on quality of life in adults and children. Aliment Pharmacol Ther. 2010;31(9):938–49.PubMed Belsey J, Greenfield S, Candy D, Geraint M. Systematic review: impact of constipation on quality of life in adults and children. Aliment Pharmacol Ther. 2010;31(9):938–49.PubMed
9.
go back to reference Dennison C, Prasad M, Lloyd A, Bhattacharaya SK, Dhawan R, Coyne K. The health-related quality of life and economic burden of constipation. Pharmacoeconomics. 2005;23(5):461–76.CrossRef Dennison C, Prasad M, Lloyd A, Bhattacharaya SK, Dhawan R, Coyne K. The health-related quality of life and economic burden of constipation. Pharmacoeconomics. 2005;23(5):461–76.CrossRef
10.
go back to reference Johnson DA. Treating chronic constipation. Clin Drug Investig. 2006;26(10):547–57.CrossRef Johnson DA. Treating chronic constipation. Clin Drug Investig. 2006;26(10):547–57.CrossRef
11.
go back to reference Barnes J, Coleman B, Hwang S, Stolic A, Bousvaros A, Nurko S, et al. Educational needs in the diagnosis and management of pediatric functional constipation: a US survey of specialist and primary care clinicians. Postgrad Med. 2018;130(4):428–35.CrossRef Barnes J, Coleman B, Hwang S, Stolic A, Bousvaros A, Nurko S, et al. Educational needs in the diagnosis and management of pediatric functional constipation: a US survey of specialist and primary care clinicians. Postgrad Med. 2018;130(4):428–35.CrossRef
12.
go back to reference Koppen IJN, Vriesman MH, Tabbers MM, Di Lorenzo C, Benninga MA. Awareness and implementation of the 2014 ESPGHAN/NASPGHAN guideline for childhood functional constipation. J Pediatr Gastroenterol Nutr. 2018;66(5):732–7.CrossRef Koppen IJN, Vriesman MH, Tabbers MM, Di Lorenzo C, Benninga MA. Awareness and implementation of the 2014 ESPGHAN/NASPGHAN guideline for childhood functional constipation. J Pediatr Gastroenterol Nutr. 2018;66(5):732–7.CrossRef
13.
go back to reference Yang CH, Punati J. Practice patterns of pediatricians and trainees for the management of functional constipation compared with 2006 NASPGHAN guidelines. J Pediatr Gastroenterol Nutr. 2015;60(3):308–11.CrossRef Yang CH, Punati J. Practice patterns of pediatricians and trainees for the management of functional constipation compared with 2006 NASPGHAN guidelines. J Pediatr Gastroenterol Nutr. 2015;60(3):308–11.CrossRef
14.
go back to reference Hasosah M, Telmesani A, Al-Binali A, Sarkhi A, Alghamdi S, Alquair K, et al. Knowledge and practice styles of pediatricians in Saudi Arabia regarding childhood constipation. J Pediatr Gastroenterol Nutr. 2013;57(1):85–92.CrossRef Hasosah M, Telmesani A, Al-Binali A, Sarkhi A, Alghamdi S, Alquair K, et al. Knowledge and practice styles of pediatricians in Saudi Arabia regarding childhood constipation. J Pediatr Gastroenterol Nutr. 2013;57(1):85–92.CrossRef
15.
go back to reference Scarpato E, Quitadamo P, Roman E, Jojkic-Pavkov D, Kolacek S, Papadopoulou A, et al. Functional gastrointestinal disorders in children: a survey on clinical approach in the Mediterranean area. J Pediatr Gastroenterol Nutr. 2017;64(6):e142–e6.CrossRef Scarpato E, Quitadamo P, Roman E, Jojkic-Pavkov D, Kolacek S, Papadopoulou A, et al. Functional gastrointestinal disorders in children: a survey on clinical approach in the Mediterranean area. J Pediatr Gastroenterol Nutr. 2017;64(6):e142–e6.CrossRef
16.
go back to reference Michel MC, Murphy TJ, Motulsky HJ. New author guidelines for displaying data and reporting data analysis and statistical methods in experimental biology. J Pharmacol Exp Ther. 2020;372(1):136–47.CrossRef Michel MC, Murphy TJ, Motulsky HJ. New author guidelines for displaying data and reporting data analysis and statistical methods in experimental biology. J Pharmacol Exp Ther. 2020;372(1):136–47.CrossRef
17.
go back to reference Oh SJ, Fuller G, Patel D, Khalil C, Spalding W, Nag A, et al. Chronic constipation in the United States: results from a population-based survey assessing healthcare seeking and use of pharmacotherapy. Am J Gastroenterol. 2020;115:895–905.CrossRef Oh SJ, Fuller G, Patel D, Khalil C, Spalding W, Nag A, et al. Chronic constipation in the United States: results from a population-based survey assessing healthcare seeking and use of pharmacotherapy. Am J Gastroenterol. 2020;115:895–905.CrossRef
18.
go back to reference Bellini M, Usai-Satta P, Bove A, Bocchini R, Galeazzi F, Battaglia E, et al. Chronic constipation diagnosis and treatment evaluation: the “CHRO.CO.DI.T.E.” study. BMC Gastroenterol. 2017;17(1):11.CrossRef Bellini M, Usai-Satta P, Bove A, Bocchini R, Galeazzi F, Battaglia E, et al. Chronic constipation diagnosis and treatment evaluation: the “CHRO.CO.DI.T.E.” study. BMC Gastroenterol. 2017;17(1):11.CrossRef
19.
go back to reference Basilisco G, Group tISoNMS. Patient dissatisfaction with medical therapy for chronic constipation or irritable bowel syndrome with constipation: analysis of N-of-1 prospective trials in 81 patients. Aliment Pharmacol Ther. 2020;51(6):629–36.CrossRef Basilisco G, Group tISoNMS. Patient dissatisfaction with medical therapy for chronic constipation or irritable bowel syndrome with constipation: analysis of N-of-1 prospective trials in 81 patients. Aliment Pharmacol Ther. 2020;51(6):629–36.CrossRef
20.
go back to reference Bellini M, Gambaccini D, Salvadori S, Tosetti C, Urbano MT, Costa F, et al. Management of chronic constipation in general practice. Tech Coloproctol. 2014;18(6):543–9.PubMed Bellini M, Gambaccini D, Salvadori S, Tosetti C, Urbano MT, Costa F, et al. Management of chronic constipation in general practice. Tech Coloproctol. 2014;18(6):543–9.PubMed
21.
go back to reference Waterfield J. Laxatives: choice, mode of action and prescribing issues. Nurse Prescribing. 2007;5(10):456–61.CrossRef Waterfield J. Laxatives: choice, mode of action and prescribing issues. Nurse Prescribing. 2007;5(10):456–61.CrossRef
22.
go back to reference Portalatin M, Winstead N. Medical management of constipation. Clin Colon Rectal Surg. 2012;25(1):12–9.CrossRef Portalatin M, Winstead N. Medical management of constipation. Clin Colon Rectal Surg. 2012;25(1):12–9.CrossRef
23.
go back to reference Müller-Lissner S, Pehl C. Laxanziengebrauch und Zufriedenheit chronisch obstipierter Frauen – eine Umfrage bei Patientinnen und Gastroenterologen in Deutschland. Z Gastroenterol. 2012;50(06):573–7.CrossRef Müller-Lissner S, Pehl C. Laxanziengebrauch und Zufriedenheit chronisch obstipierter Frauen – eine Umfrage bei Patientinnen und Gastroenterologen in Deutschland. Z Gastroenterol. 2012;50(06):573–7.CrossRef
24.
go back to reference Müller-Lissner S, Richter E, Eberlin M, Weigmann H, Mück T, Kamm MA. Bisacodyl and sodium picosulfate improve bowel function and quality of life in patients with chronic constipation - analysis of pooled data from two randomized controlled trials. Open J Gastroenterol. 2017;7:32–43.CrossRef Müller-Lissner S, Richter E, Eberlin M, Weigmann H, Mück T, Kamm MA. Bisacodyl and sodium picosulfate improve bowel function and quality of life in patients with chronic constipation - analysis of pooled data from two randomized controlled trials. Open J Gastroenterol. 2017;7:32–43.CrossRef
Metadata
Title
Impact of guideline awareness in public pharmacies on counseling of patients with acute or chronic constipation in a survey of pharmacy personnel
Authors
Marion Eberlin
Sabine Landes
Doerthe Biber-Feiter
Martin C. Michel
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Gastroenterology / Issue 1/2020
Electronic ISSN: 1471-230X
DOI
https://doi.org/10.1186/s12876-020-01338-4

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