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Journal of Gastrointestinal Surgery

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01-06-2013 | Original Article

Conservative Therapeutic Approach to Corrosive Poisonings in Adults

Authors: A. Chibishev, Z. Pereska, N. Simonovska, V. Chibisheva, M. Glasnovic, L. T. Chitkushev

Published in: Journal of Gastrointestinal Surgery | Issue 6/2013

Abstract

Introduction

In this study, we assess the effectiveness of a conservative therapeutic treatment of acute corrosive poisonings in adults, and we define therapeutic protocols based on clinical and endoscopic criteria.

Methods

We analyzed clinical records of patients with acute corrosive poisonings who were hospitalized and treated at the Toxicology Clinic at the University of Skopje, Republic of Macedonia, during a 5-year period (2006–2010). A total of 481 patients’ records with cases of acute corrosive poisonings were analyzed. There were 317 female (65.9 %) and 164 male (34.1 %) patients. The purpose of the therapy in the cases of acute corrosive poisonings is to prevent perforation as well as progressive fibrosis and stenosis of the esophagus and stomach. Therapeutic approach mainly consists of proton pump inhibitors, H₂ blockers, antibiotics, and intensive hyperalimentation. There are different opinions regarding conservative treatment of acute corrosive poisonings in adults.

Conclusion

Based on our study of corrosive poisonings of adults, we propose a list of optimal treatment recommendations.

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Title: Conservative Therapeutic Approach to Corrosive Poisonings in Adults
Authors: A. Chibishev
Z. Pereska
N. Simonovska
V. Chibisheva
M. Glasnovic
L. T. Chitkushev
Publication date: 01-06-2013
Publisher: Springer-Verlag
Published in: Journal of Gastrointestinal Surgery / Issue 6/2013
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-013-2190-9

At a glance: The STEP trials

Springer Medicine

Conservative Therapeutic Approach to Corrosive Poisonings in Adults

Abstract

Introduction

Methods

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Introduction

Methods

Conclusion

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