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01-06-2015 | Original Article

Connective tissue graft as a biological barrier for guided tissue regeneration in intrabony defects: a histological study in dogs

Authors: Fernando Salimon Ribeiro, Ana Emília Farias Pontes, Elizangela Partata Zuza, Vanessa Camila da Silva, Raphael Carlos Comelli Lia, Elcio Marcantonio Junior

Published in: Clinical Oral Investigations | Issue 5/2015

Abstract

Background

The use of the autogenous periosteal graft as biological barrier has been proposed for periodontal regeneration. The aim of this study was to evaluate the histometric findings of the subepithelial connective tissue graft as barrier in intrabony defects compared to a bioabsorbable membrane.

Methods

Three-walled intrabony defects were created surgically in the mesial aspect of the right and left maxillary canines in five healthy mongrel dogs. The defects were chronified, and two types of barriers were randomly carried out for guided tissue regeneration in a split-mouth design: the test group with a subepithelial connective tissue graft and the control group with a bioabsorbable membrane. The specimens were processed for histometric analyses of the epithelium (E), connective tissue (CT), newly formed cementum (NC), new bone (NB), and total newly formed tissues (NFT).

Results

The test side showed smaller mean of NC (3.6 ± 1.2), NB (2.1 ± 0.7), and NFT (7.7 ± 0.8) than the control group (NC 7.3 ± 0.5; NB 5.3 ± 1.3; NFT 10.1 ± 2.2; P < 0.05). No statistically significant differences were verified for E (test 3.1 ± 2.0; control 2.8 ± 2.1; P > 0.05) and CT (test 2.5 ± 1.1; control 2.0 ± 0.5; P > 0.05) between groups.

Conclusion

The bioabsorbable membrane was more effective in maintaining the space for periodontal regeneration than periosteal connective graft when used as barrier.

Clinical relevance

The bioabsorbable membrane showed more favorable regenerative results in intrabony defects in dogs than the subepithelial connective tissue graft as biological barrier.

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Title: Connective tissue graft as a biological barrier for guided tissue regeneration in intrabony defects: a histological study in dogs
Authors: Fernando Salimon Ribeiro
Ana Emília Farias Pontes
Elizangela Partata Zuza
Vanessa Camila da Silva
Raphael Carlos Comelli Lia
Elcio Marcantonio Junior
Publication date: 01-06-2015
Publisher: Springer Berlin Heidelberg
Published in: Clinical Oral Investigations / Issue 5/2015
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-014-1323-1

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Springer Medicine

Connective tissue graft as a biological barrier for guided tissue regeneration in intrabony defects: a histological study in dogs

Abstract

Background

Methods

Results

Conclusion

Clinical relevance

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

Clinical relevance

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