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Diagnostic Pathology

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Open Access 01-12-2023 | Conjunctivitis | Case Report

A case of IgG4-positive ligneous conjunctivitis mistaken for a conjunctival mass

Authors: Jing Li, Rui Liu, Tingting Ren, Hong Zhang, Jianmin Ma

Published in: Diagnostic Pathology | Issue 1/2023

Abstract

Background

Ligneous conjunctivitis (LC) is a rare inflammatory lesion of the conjunctiva with an unknown etiology. It is easily confused with conjunctiva lymphoma or other diseases in clinical diagnosis, and the lesion is very difficult to treat.

Case presentation

We presented a 41-year-old female patient presented with bilateral conjunctival masses for more than six months. The patient had no contributory history of ocular trauma, family history of tumor and drug allergy. Taking the patient’s clinical and pathological features together, we considered this was a case of IgG4 + LC. Completely surgical resection combined with local glucocorticoid treatment might be effective.

Conclusions

This is a very rare case report of immunoglobulin G4 positive LC with only one published case in literature. The typical manifestations of LC are with the appearance of a hard, fibrin-rich, woody pseudomembranous lesion. A large number of lymphocyte and plasma cell are infiltrated in the pathological tissue. Inflammation of LC may cause immune abnormalities, resulting in IgG4 increasing.

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Title: A case of IgG4-positive ligneous conjunctivitis mistaken for a conjunctival mass
Authors: Jing Li
Rui Liu
Tingting Ren
Hong Zhang
Jianmin Ma
Publication date: 01-12-2023
Publisher: BioMed Central
Keywords: Conjunctivitis
Glucocorticoid
Published in: Diagnostic Pathology / Issue 1/2023
Electronic ISSN: 1746-1596
DOI: https://doi.org/10.1186/s13000-023-01366-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

A case of IgG4-positive ligneous conjunctivitis mistaken for a conjunctival mass

Abstract

Background

Case presentation

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Case presentation

Conclusions

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