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Published in: European Radiology 6/2005

01-06-2005 | Cardiac

Congenital anomalies of the coronary arteries: imaging with contrast-enhanced, multidetector computed tomography

Authors: Rainer Schmitt, Steffen Froehner, Juergen Brunn, Matthias Wagner, Horst Brunner, Oleg Cherevatyy, Frank Gietzen, Georgios Christopoulos, Sebastian Kerber, Franz Fellner

Published in: European Radiology | Issue 6/2005

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Abstract

The objective of this study is to evaluate multidetector CT (MDCT) in detecting and characterizing anomalous coronary arteries. Forty-four patients with anomalies of the coronaries were selected from a total of 1758 individuals examined with ECG-gated 4- and 16-row MDCT including thinMIP, MPR and VRT post-processing. Twenty-eight patients showed origin and course anomalies of the central coronary segments, and in this subgroup 13 were judged as “malignant” because of interarterial courses between the aortic root and the pulmonary trunk, either of the right coronary artery (n=11) or the left coronary artery (n=2). Twelve non-hemodynamic anomalies were found, affecting the coronary origins only (n=10) or the peripheral vessels courses (n=2). Four arteriovenous fistulas were present, all of them with complex arterial feeders. Regardless of vessel anatomy, coronary opacification was always possible by means of the systemic contrast agent, and the aberrant coronary arteries were visualized synoptically in direct relation to the great mediastinal vessels. In contrast to MDCT, selective cannulation and final diagnosis was possible in only 11 of the 20 catheter angiograms performed (accuracy of 55.0%). In conclusion, its non-invasiveness and precise visualization makes MDCT the standard of reference for evaluating anomalous coronary arteries.
Literature
1.
go back to reference Smith GT (1962) The anatomy of the coronary circulation. Am J Cardiol 9:327–342 Smith GT (1962) The anatomy of the coronary circulation. Am J Cardiol 9:327–342
2.
go back to reference Waller BF, Orr CM, Slack JD, Pinkerton CA, Van Tassel J, Peters T (1992) Anatomy, histology and pathology of coronary arteries: a review relevant to new interventional and imaging techniques: part I. Clin Cardiol 15:451–457 Waller BF, Orr CM, Slack JD, Pinkerton CA, Van Tassel J, Peters T (1992) Anatomy, histology and pathology of coronary arteries: a review relevant to new interventional and imaging techniques: part I. Clin Cardiol 15:451–457
3.
go back to reference Baltaxe HA, Wixson D (1977) The incidence of congenital anomalies of the coronary arteries in the adult population. Radiology 122:47–52 Baltaxe HA, Wixson D (1977) The incidence of congenital anomalies of the coronary arteries in the adult population. Radiology 122:47–52
4.
go back to reference Chaitman BR, Lesperance J, Saltiel J, Bourassa MG (1976) Clinical, angiographic, and hemodynamic findings in patients with anomalous origin of the coronary arteries. Circulation 53:122–131 Chaitman BR, Lesperance J, Saltiel J, Bourassa MG (1976) Clinical, angiographic, and hemodynamic findings in patients with anomalous origin of the coronary arteries. Circulation 53:122–131
5.
go back to reference Engel HJ, Torres C, Page HL (1975) Major variations in anatomical origin of the coronary arteries: angiographic observations in 4,250 patients without associated congenital heart disease. Catheter Cardiovasc Diagn 1:157–169 Engel HJ, Torres C, Page HL (1975) Major variations in anatomical origin of the coronary arteries: angiographic observations in 4,250 patients without associated congenital heart disease. Catheter Cardiovasc Diagn 1:157–169
6.
go back to reference Garg N, Tewari S, Kapoor A, Gupta DK, Sinha N (2000) Primary congenital anomalies of the coronary arteries: a coronary arteriographic study. Int J Cardiol 74:39–46 Garg N, Tewari S, Kapoor A, Gupta DK, Sinha N (2000) Primary congenital anomalies of the coronary arteries: a coronary arteriographic study. Int J Cardiol 74:39–46
7.
go back to reference Kimbiris D, Iskandrian AS, Segal BL, Bemin CE (1978) Anomalous aortic origin of coronary arteries. Circulation 58:606–615 Kimbiris D, Iskandrian AS, Segal BL, Bemin CE (1978) Anomalous aortic origin of coronary arteries. Circulation 58:606–615
8.
go back to reference Levin DC, Fellows KE, Abrams HL (1978) Hemodynamically significant primary anomalies of the coronary arteries. Angiographic aspects. Circulation 58:25–34 Levin DC, Fellows KE, Abrams HL (1978) Hemodynamically significant primary anomalies of the coronary arteries. Angiographic aspects. Circulation 58:25–34
9.
go back to reference Liberthson RR, Dinsmore RE, Fallon JT (1979) Aberrant coronary artery origin from the aorta. Report of 18 patients, review of literature and delineation of natural history and management. Circulation 59:748–754 Liberthson RR, Dinsmore RE, Fallon JT (1979) Aberrant coronary artery origin from the aorta. Report of 18 patients, review of literature and delineation of natural history and management. Circulation 59:748–754
10.
go back to reference Yamanaka O, Hobbs RE (1990) Coronary artery anomalies in 126.595 patients undergoing coronary arteriography. Catheter Cardiovasc Diagn 21:28–40 Yamanaka O, Hobbs RE (1990) Coronary artery anomalies in 126.595 patients undergoing coronary arteriography. Catheter Cardiovasc Diagn 21:28–40
11.
go back to reference Wesselhoeft H, Fawcett JS, Johnson AL (1968) Anomalous origin of the left coronary artery from the pulmonary trunk. Its clinical spectrum, pathology and pathophysiology, based on a review of 140 cases with seven further cases. Circulation 38:403–425 Wesselhoeft H, Fawcett JS, Johnson AL (1968) Anomalous origin of the left coronary artery from the pulmonary trunk. Its clinical spectrum, pathology and pathophysiology, based on a review of 140 cases with seven further cases. Circulation 38:403–425
12.
go back to reference Cheitlin MD, De Castro CM, McAllister HA (1974) Sudden death as a complication of anomalous left coronary origin from the anterior sinus of Valsalva. A not-so-minor congenital anomaly. Circulation 50:780–787 Cheitlin MD, De Castro CM, McAllister HA (1974) Sudden death as a complication of anomalous left coronary origin from the anterior sinus of Valsalva. A not-so-minor congenital anomaly. Circulation 50:780–787
13.
go back to reference Ishikawa T, Brandt PW (1985) Anomalous origin of the left main coronary artery from the right anterior aortic sinus: angiographic definition of anomalous course. Am J Cardiol 55:770–776 Ishikawa T, Brandt PW (1985) Anomalous origin of the left main coronary artery from the right anterior aortic sinus: angiographic definition of anomalous course. Am J Cardiol 55:770–776
14.
go back to reference Serota H, Barth CW III, Seuc CA, Vandormael F, Aguirre F, Kern MJ (1990) Rapid identification of the course of anomalous coronary arteries in adults: the “dot and eye” method. Am J Cardiol 65:891–898CrossRefPubMed Serota H, Barth CW III, Seuc CA, Vandormael F, Aguirre F, Kern MJ (1990) Rapid identification of the course of anomalous coronary arteries in adults: the “dot and eye” method. Am J Cardiol 65:891–898CrossRefPubMed
15.
go back to reference Taylor AM, Thorne SA, Rubens MP, Jhooti P, Keegan J, Gatehouse PD, Wiesmann F, Grothues F, Somerville J, Pennell DJ (2000) Coronary artery imaging in grown up congenital heart disease: complementary role of magnetic resonance and x-ray coronary angiography. Circulation 101:1670–1678 Taylor AM, Thorne SA, Rubens MP, Jhooti P, Keegan J, Gatehouse PD, Wiesmann F, Grothues F, Somerville J, Pennell DJ (2000) Coronary artery imaging in grown up congenital heart disease: complementary role of magnetic resonance and x-ray coronary angiography. Circulation 101:1670–1678
16.
go back to reference Kragel AH, Roberts WC (1988) Anomalous origin of either the right or left main coronary artery from the aorta with subsequent coursing between aorta and pulmonary trunk: analysis of 32 necropsy cases. Am J Cardiol 62:771–777 Kragel AH, Roberts WC (1988) Anomalous origin of either the right or left main coronary artery from the aorta with subsequent coursing between aorta and pulmonary trunk: analysis of 32 necropsy cases. Am J Cardiol 62:771–777
17.
go back to reference Roberts WC (1986) Major anomalies of coronary arterial origin seen in adulthood. Am Heart J 111:941–963CrossRef Roberts WC (1986) Major anomalies of coronary arterial origin seen in adulthood. Am Heart J 111:941–963CrossRef
18.
go back to reference Basso C, Maron BJ, Corrado D, Thiene G (2000) Clinical profile of congenital coronary artery anomalies with origin from the wrong aortic sinus leading to sudden death in young competitive athletes. J Am Coll Cardiol 35:1493–1501CrossRefPubMed Basso C, Maron BJ, Corrado D, Thiene G (2000) Clinical profile of congenital coronary artery anomalies with origin from the wrong aortic sinus leading to sudden death in young competitive athletes. J Am Coll Cardiol 35:1493–1501CrossRefPubMed
19.
go back to reference McConnell MV, Stuber M, Manning WJ (2000) Clinical role of coronary magnetic resonance angiography in the diagnosis of anomalous coronary arteries. J Cardiovasc Magn Reson 2:217–224 McConnell MV, Stuber M, Manning WJ (2000) Clinical role of coronary magnetic resonance angiography in the diagnosis of anomalous coronary arteries. J Cardiovasc Magn Reson 2:217–224
20.
21.
go back to reference Cox ID, Bunce N, Fluck DS (2000) Failed sudden cardiac death in a patient with an anomalous origin of the right coronary artery. Circulation 102:1461–1462 Cox ID, Bunce N, Fluck DS (2000) Failed sudden cardiac death in a patient with an anomalous origin of the right coronary artery. Circulation 102:1461–1462
22.
go back to reference Ropers D, Moshage W, Daniel WG, Jessl J, Gottwik M, Achenbach S (2001) Visualization of coronary artery anomalies and their anatomic course by contrast-enhanced electron beam tomography and three-dimensional reconstruction. Am J Cardiol 87:193–197CrossRefPubMed Ropers D, Moshage W, Daniel WG, Jessl J, Gottwik M, Achenbach S (2001) Visualization of coronary artery anomalies and their anatomic course by contrast-enhanced electron beam tomography and three-dimensional reconstruction. Am J Cardiol 87:193–197CrossRefPubMed
23.
go back to reference Yoshimura N, Hamada S, Takamiya M, Kuribayashi S, Kimura K (1998) Coronary artery anomalies with a shunt: evaluation with electron-beam CT. J Comput Assist Tomogr 22:682–686 Yoshimura N, Hamada S, Takamiya M, Kuribayashi S, Kimura K (1998) Coronary artery anomalies with a shunt: evaluation with electron-beam CT. J Comput Assist Tomogr 22:682–686
24.
go back to reference Post JC, van Rossum AC, Bronzwaer JG, de Cock CC, Hofman MBM, Valk J, Visser CA (1995) Magnetic resonance angiography of anomalous coronary arteries. A new gold standard for delineating the proximal course? Circulation 92:3163–3171 Post JC, van Rossum AC, Bronzwaer JG, de Cock CC, Hofman MBM, Valk J, Visser CA (1995) Magnetic resonance angiography of anomalous coronary arteries. A new gold standard for delineating the proximal course? Circulation 92:3163–3171
25.
go back to reference Bunce NH, Lorenz CH, Keegan J, Lesser J, Reyes EM, Firmin DN, Pennell DJ (2003) Coronary artery anomalies: assessment with free-breathing three-dimensional coronary MR angiography. Radiology 227:201–208 Bunce NH, Lorenz CH, Keegan J, Lesser J, Reyes EM, Firmin DN, Pennell DJ (2003) Coronary artery anomalies: assessment with free-breathing three-dimensional coronary MR angiography. Radiology 227:201–208
26.
go back to reference Hamoir XL, Flohr T, Hamoir V, Labaki L, Triquet JY, Duhamel A, Kirsch J (2005) Coronary arteries: assessment of image quality and optimal reconstruction window in retrospective ECG-gated multislice CT at 375-ms gantry rotation time. Eur Radiol 15:296–304 Hamoir XL, Flohr T, Hamoir V, Labaki L, Triquet JY, Duhamel A, Kirsch J (2005) Coronary arteries: assessment of image quality and optimal reconstruction window in retrospective ECG-gated multislice CT at 375-ms gantry rotation time. Eur Radiol 15:296–304
27.
go back to reference Shi H, Aschoff AJ, Brambs HJ, Hoffmann MK (2004) Multislice CT imaging of anomalous coronary arteries. Eur Radiol 14:2172–2181 Shi H, Aschoff AJ, Brambs HJ, Hoffmann MK (2004) Multislice CT imaging of anomalous coronary arteries. Eur Radiol 14:2172–2181
28.
go back to reference van Ooijen PMA, Dorgelo J, Zijlstra F, Oudkerk M (2004) Detection, visualization and evaluation of anomalous coronary anatomy on 16-slice multidetector-row CT. Eur Radiol 14:2163–2171 van Ooijen PMA, Dorgelo J, Zijlstra F, Oudkerk M (2004) Detection, visualization and evaluation of anomalous coronary anatomy on 16-slice multidetector-row CT. Eur Radiol 14:2163–2171
29.
go back to reference Kachelriess M, Ulzheimer S, Kalender WA (2000) ECG-correlated image reconstruction from subsecond multi-slice spiral CT scans of the heart. Med Phys 27:1881–1902CrossRefPubMed Kachelriess M, Ulzheimer S, Kalender WA (2000) ECG-correlated image reconstruction from subsecond multi-slice spiral CT scans of the heart. Med Phys 27:1881–1902CrossRefPubMed
30.
go back to reference Reddy GP, Chernoff DM, Adams JR, Higgins CB (1998) Coronary artery stenoses: assessment with contrast-enhanced electron-beam CT and axial reconstructions. Radiology 208:167–172 Reddy GP, Chernoff DM, Adams JR, Higgins CB (1998) Coronary artery stenoses: assessment with contrast-enhanced electron-beam CT and axial reconstructions. Radiology 208:167–172
31.
go back to reference Click RL, Holmes DR Jr, Vlietstra RE, Kosinski AS, Kronmal RA (1989) Anomalous coronary arteries: location, degree of atherosclerosis and effect on survival—a report from the Coronary Artery Surgery Group. J Am Coll Cardiol 13:531–537 Click RL, Holmes DR Jr, Vlietstra RE, Kosinski AS, Kronmal RA (1989) Anomalous coronary arteries: location, degree of atherosclerosis and effect on survival—a report from the Coronary Artery Surgery Group. J Am Coll Cardiol 13:531–537
32.
go back to reference Dicicco BS, McManus BM, Waller BF, Roberts WC (1982) Separate aortic ostium of the left anterior descending and left circumflex coronary arteries from the left aortic sinus of Valsalva (absent left main coronary artery). Am Heart J 104:153–154 Dicicco BS, McManus BM, Waller BF, Roberts WC (1982) Separate aortic ostium of the left anterior descending and left circumflex coronary arteries from the left aortic sinus of Valsalva (absent left main coronary artery). Am Heart J 104:153–154
33.
go back to reference Topaz O, DeMarchena EJ, Perin E, Sommer LS, Mallon SM, Chahine RA (1992) Anomalous coronary arteries: angiographic findings in 80 patients. Int J Cardiol 34:129–138 Topaz O, DeMarchena EJ, Perin E, Sommer LS, Mallon SM, Chahine RA (1992) Anomalous coronary arteries: angiographic findings in 80 patients. Int J Cardiol 34:129–138
34.
go back to reference Le T, Laskey WK, McLaughin J, White C (1997) Utility of magnetic resonance imaging in a patient with anomalous origin of the right coronary artery, acute myocardial infarction, and near-sudden cardiac death. Catheter Cardiovasc Diagn 42:205–207 Le T, Laskey WK, McLaughin J, White C (1997) Utility of magnetic resonance imaging in a patient with anomalous origin of the right coronary artery, acute myocardial infarction, and near-sudden cardiac death. Catheter Cardiovasc Diagn 42:205–207
35.
go back to reference Frescura C, Basso C, Thiene G, Corrado D, Pennelli T, Angelini A, Daliento L (1998) Anomalous origin of coronary arteries and risk of sudden death: a study based on an autopsy population of congenital heart disease. Hum Pathol 29:689–695CrossRefPubMed Frescura C, Basso C, Thiene G, Corrado D, Pennelli T, Angelini A, Daliento L (1998) Anomalous origin of coronary arteries and risk of sudden death: a study based on an autopsy population of congenital heart disease. Hum Pathol 29:689–695CrossRefPubMed
36.
go back to reference Roberts WC, Siegel RJ, Zipes DP (1982) Origin of the right coronary artery from the left sinus of valsalva and its functional consequences: analysis of 10 necropsy patients. Am J Cardiol 49:863–868 Roberts WC, Siegel RJ, Zipes DP (1982) Origin of the right coronary artery from the left sinus of valsalva and its functional consequences: analysis of 10 necropsy patients. Am J Cardiol 49:863–868
37.
go back to reference Thompson SI, Vieweg WV, Alpert JS, Hagan AD (1976) Anomalous origin of the right coronary artery from the left sinus of Valsalva with associated chest pain: report of two cases. Catheter Cardiovasc Diagn 2:397–402 Thompson SI, Vieweg WV, Alpert JS, Hagan AD (1976) Anomalous origin of the right coronary artery from the left sinus of Valsalva with associated chest pain: report of two cases. Catheter Cardiovasc Diagn 2:397–402
38.
go back to reference Roberts WC, Dicicco BS, Waller BF, Kishel JC, McManus BM, Dawson SL, Hunsaker JC III, Luke JL (1982) Origin of the left main from the right coronary artery or from the right aortic sinus with intramyocardial tunneling to the left side of the heart via the ventricular septum. The case against clinical significance of myocardial bridge or coronary tunnel. Am Heart J 104:303–305 Roberts WC, Dicicco BS, Waller BF, Kishel JC, McManus BM, Dawson SL, Hunsaker JC III, Luke JL (1982) Origin of the left main from the right coronary artery or from the right aortic sinus with intramyocardial tunneling to the left side of the heart via the ventricular septum. The case against clinical significance of myocardial bridge or coronary tunnel. Am Heart J 104:303–305
39.
go back to reference Roberts WC, Kragel AH (1988) Anomalous origin of either the right or left main coronary artery from the aorta without coursing of the anomalistically arising artery between aorta and pulmonary trunk. Am J Cardiol 62:1263–1267 Roberts WC, Kragel AH (1988) Anomalous origin of either the right or left main coronary artery from the aorta without coursing of the anomalistically arising artery between aorta and pulmonary trunk. Am J Cardiol 62:1263–1267
40.
go back to reference Page HL Jr, Engel HJ, Campbell WB, Thomas CS Jr (1974) Anomalous origin of the left circumflex coronary artery. Recognition, angiographic demonstration and clinical significance. Circulation 50:768–773 Page HL Jr, Engel HJ, Campbell WB, Thomas CS Jr (1974) Anomalous origin of the left circumflex coronary artery. Recognition, angiographic demonstration and clinical significance. Circulation 50:768–773
41.
go back to reference Samarendra P, Kumari S, Hafeez M, Vasavada BC, Sacchi TJ (2001) Anomalous circumflex coronary artery: benign or predisposed to selective atherosclerosis. Angiology 52:521–526 Samarendra P, Kumari S, Hafeez M, Vasavada BC, Sacchi TJ (2001) Anomalous circumflex coronary artery: benign or predisposed to selective atherosclerosis. Angiology 52:521–526
42.
go back to reference Silverman KJ, Bulkley BH, Hutchins GM (1978) Anomalous left circumflex coronary artery: “normal” variant of uncertain clinical and pathologic significance. Am J Cardiol 41:1311–1314 Silverman KJ, Bulkley BH, Hutchins GM (1978) Anomalous left circumflex coronary artery: “normal” variant of uncertain clinical and pathologic significance. Am J Cardiol 41:1311–1314
43.
go back to reference Ueno T, Nakayama Y, Yoshikai M, Watanabe Y, Minato N, Natsuaki M, Itoh T (1992) Unique manifestation of congenital coronary artery fistulas. Am Heart J 124:1388–1391 Ueno T, Nakayama Y, Yoshikai M, Watanabe Y, Minato N, Natsuaki M, Itoh T (1992) Unique manifestation of congenital coronary artery fistulas. Am Heart J 124:1388–1391
44.
go back to reference Kamiya H, Yasuda T, Nagamine H, Sakakibara N, Nishida S, Kawasuji M, Watanabe G (2002) Surgical treatment of congenital coronary artery fistulas: 27 years’ experience and a review of the literature. J Card Surg 17:173–177 Kamiya H, Yasuda T, Nagamine H, Sakakibara N, Nishida S, Kawasuji M, Watanabe G (2002) Surgical treatment of congenital coronary artery fistulas: 27 years’ experience and a review of the literature. J Card Surg 17:173–177
45.
go back to reference Dirksen MS, Langerak SE, de Roos A, Vliegen HW, Jukema JW, Bax JJ, Wielopolski PA, van der Wall EE, Lamb HJ (2002) Images in cardiovascular medicine. Malignant right coronary artery anomaly detected by magnetic resonance angiography. Circulation 106:1881–1882 Dirksen MS, Langerak SE, de Roos A, Vliegen HW, Jukema JW, Bax JJ, Wielopolski PA, van der Wall EE, Lamb HJ (2002) Images in cardiovascular medicine. Malignant right coronary artery anomaly detected by magnetic resonance angiography. Circulation 106:1881–1882
Metadata
Title
Congenital anomalies of the coronary arteries: imaging with contrast-enhanced, multidetector computed tomography
Authors
Rainer Schmitt
Steffen Froehner
Juergen Brunn
Matthias Wagner
Horst Brunner
Oleg Cherevatyy
Frank Gietzen
Georgios Christopoulos
Sebastian Kerber
Franz Fellner
Publication date
01-06-2005
Publisher
Springer-Verlag
Published in
European Radiology / Issue 6/2005
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-005-2707-z

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