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Open Access 01-03-2010 | Breast

Computer-aided detection (CAD) for breast MRI: evaluation of efficacy at 3.0 T

Authors: Carla Meeuwis, Stephanie M. van de Ven, Gerard Stapper, Arancha M. Fernandez Gallardo, Maurice A. A. J. van den Bosch, Willem P. Th. M. Mali, Wouter B. Veldhuis

Published in: European Radiology | Issue 3/2010

Abstract

Objective

The purpose of the study was to evaluate the accuracy of 3.0-T breast MRI interpretation using manual and fully automated kinetic analyses.

Material and methods

Manual MRI interpretation was done on an Advantage Workstation. Retrospectively, all examinations were processed with a computer-aided detection (CAD) system. CAD data sets were interpreted by two experienced breast radiologists and two residents. For each lesion automated analysis of enhancement kinetics was evaluated at 50% and 100% thresholds. Forty-nine malignant and 22 benign lesions were evaluated.

Results

Using threshold enhancement alone, the sensitivity and specificity of CAD were 97.9% and 86.4%, respectively, for the 50% threshold, and 97.9% and 90%, respectively, for the 100% threshold. Manual interpretation by two breast radiologists showed a sensitivity of 84.6% and a specificity of 68.8%. For the same two radiologists the mean sensitivity and specificity for CAD-based interpretation was 90.4% (not significant) and 81.3% (significant at p < 0.05), respectively. With one-way ANOVA no significant differences were found between the two breast radiologists and the two residents together, or between any two readers separately.

Conclusion

CAD-based analysis improved the specificity compared with manual analysis of enhancement. Automated analysis at 50% and 100% thresholds showed a high sensitivity and specificity for readers with varying levels of experience.

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Title: Computer-aided detection (CAD) for breast MRI: evaluation of efficacy at 3.0 T
Authors: Carla Meeuwis
Stephanie M. van de Ven
Gerard Stapper
Arancha M. Fernandez Gallardo
Maurice A. A. J. van den Bosch
Willem P. Th. M. Mali
Wouter B. Veldhuis
Publication date: 01-03-2010
Publisher: Springer-Verlag
Published in: European Radiology / Issue 3/2010
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-009-1573-5

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Computer-aided detection (CAD) for breast MRI: evaluation of efficacy at 3.0 T

Abstract

Objective

Material and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Material and methods

Results

Conclusion

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