Skip to main content
Top
Published in: Current Cardiovascular Imaging Reports 11/2018

01-11-2018 | Echocardiography (F Asch and S Costa, Section Editors)

Comprehensive Assessment of Aortic Stenosis in the TAVR Era

Author: Michael J. Malkowski

Published in: Current Cardiovascular Imaging Reports | Issue 11/2018

Login to get access

Abstract

Purpose of Review

Transcatheter aortic valve replacement (TAVR) has been approved for the treatment of severe aortic stenosis in patients who are prohibitive surgical risk, high surgical risk, and now intermediate surgical risk. This review aims to raise awareness of the role echocardiography in evaluating patients with aortic stenosis for TAVR, in assisting during the procedure for device placement and to identify procedural complications and in assessing follow-up valvular and cardiac function to guide ongoing therapy.

Recent Findings

A comprehensive echocardiogram is an essential part of the evaluation of patients with aortic stenosis. Severe aortic stenosis is present in patients with a peak aortic velocity of > 4 m/s, mean gradient > 40 mmHg, and AVA < 1.0 cm2. In patients with reduced LV systolic function, dobutamine echocardiography may help differentiate patients with true low-gradient aortic stenosis from patients with pseudo-aortic stenosis. Echocardiography is used in conjunction with fluoroscopy to assist with valve placement and is important in identifying procedural complications including paravalvular regurgitation. Follow-up echocardiography is strongly recommended at 30 days following the procedure and then annually to assess valvular function and hemodynamic effects following correction of the aortic stenosis.

Summary

In the TAVR era, echocardiography will play a critical role in the evaluation and treatment of the patient with aortic stenosis.
Literature
1.
go back to reference Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin IIIJP, Fleisher LA, et al. AHA/ACC focused update of the 2014 AHA/ACC guidelines for the management of patients with valvular heart disease. A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol 2017. 2017;70:252–89.CrossRef Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin IIIJP, Fleisher LA, et al. AHA/ACC focused update of the 2014 AHA/ACC guidelines for the management of patients with valvular heart disease. A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol 2017. 2017;70:252–89.CrossRef
2.
go back to reference Otto CM, Prendergast B. Aortic-valve stenosis-from patients at risk to severe valve obstruction. N Engl J Med. 2014;371:744–56.CrossRef Otto CM, Prendergast B. Aortic-valve stenosis-from patients at risk to severe valve obstruction. N Engl J Med. 2014;371:744–56.CrossRef
3.
go back to reference Douglas PS, Garcia MJ, Haines DE, Lai WW, Manning WJ, Patel AR, et al. ACCF/ASE/AHA/ASNA/HRS/SCAI/SCCM/SCCT/SCMR 2011 appropriate use criteria for echocardiography. J Am Soc Echocardiogr. 2011;24:229–67.CrossRef Douglas PS, Garcia MJ, Haines DE, Lai WW, Manning WJ, Patel AR, et al. ACCF/ASE/AHA/ASNA/HRS/SCAI/SCCM/SCCT/SCMR 2011 appropriate use criteria for echocardiography. J Am Soc Echocardiogr. 2011;24:229–67.CrossRef
4.
go back to reference • Hahn RT, Nicoara A, Kapadia S, Svensson L, Martin R. Echocardiographic imaging for transcatheter aortic valve replacement. J Am Soc Echocardiogr. 2018;31:405–33. A comprehensive review which provides detailed recommendations regarding the use of echo for intraprocedural guidance. CrossRef • Hahn RT, Nicoara A, Kapadia S, Svensson L, Martin R. Echocardiographic imaging for transcatheter aortic valve replacement. J Am Soc Echocardiogr. 2018;31:405–33. A comprehensive review which provides detailed recommendations regarding the use of echo for intraprocedural guidance. CrossRef
5.
go back to reference • Baumgartner H, Hung J, Bermejo J, Chambers JB, Edvardsen T, Goldstein S, et al. Recommendations of the echocardiographic assessment of aortic valve stenosis; a focused update from the European Association of Cardiovascular Imaging and the American Society of Echocardiography. J Am Soc Echocardiogr. 2017;30:372–92. State of the art review of the use of echocardiography to assess aortic valve stenosis. CrossRef • Baumgartner H, Hung J, Bermejo J, Chambers JB, Edvardsen T, Goldstein S, et al. Recommendations of the echocardiographic assessment of aortic valve stenosis; a focused update from the European Association of Cardiovascular Imaging and the American Society of Echocardiography. J Am Soc Echocardiogr. 2017;30:372–92. State of the art review of the use of echocardiography to assess aortic valve stenosis. CrossRef
6.
go back to reference Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin JP III, Guyton RA, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease. J Am Coll Cardiol. 2014;63:e57–185.CrossRef Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin JP III, Guyton RA, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease. J Am Coll Cardiol. 2014;63:e57–185.CrossRef
7.
go back to reference Steiner J, Rodes-Cabau J, Holmes DR, LeWinter MM, Dauerman HL. Mechanical intervention for aortic valve stenosis in patients with heart failure and reduced ejection fraction. J Am Coll Cardiol. 2017;70:3026–41.CrossRef Steiner J, Rodes-Cabau J, Holmes DR, LeWinter MM, Dauerman HL. Mechanical intervention for aortic valve stenosis in patients with heart failure and reduced ejection fraction. J Am Coll Cardiol. 2017;70:3026–41.CrossRef
8.
go back to reference Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong LP, Ernande L, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2015;28:1–39.CrossRef Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong LP, Ernande L, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2015;28:1–39.CrossRef
9.
go back to reference Clavel MA, Burwash IG, Pibarot P. Cardiac imaging for assessing low-gradient severe aortic stenosis. J Am Coll Cardiol Img. 2017;10:185–202.CrossRef Clavel MA, Burwash IG, Pibarot P. Cardiac imaging for assessing low-gradient severe aortic stenosis. J Am Coll Cardiol Img. 2017;10:185–202.CrossRef
10.
go back to reference Lancellotti P, Pellikka PA, Budts W, Chaudhry FA, Donal E, Dulgheru R, et al. The clinical use of stress echocardiography in non-ischaemic heart disease: recommendations from the European Association of Cardiovascular Imaging and the American Society of Echocardiography. J Am Soc Echocardiogr. 2017;30:010–38.CrossRef Lancellotti P, Pellikka PA, Budts W, Chaudhry FA, Donal E, Dulgheru R, et al. The clinical use of stress echocardiography in non-ischaemic heart disease: recommendations from the European Association of Cardiovascular Imaging and the American Society of Echocardiography. J Am Soc Echocardiogr. 2017;30:010–38.CrossRef
11.
go back to reference Riberiro HB, Lerakis S, Gilard M, Cavalcante JL, Makkar R, Herrmann HC, et al. Transcatheter aortic valve replacement in patients with low-flow, low-gradient aortic stenosis. The TOPAS-TAVI Registry. J Am Coll Cardiol. 2018;71:1297–308.CrossRef Riberiro HB, Lerakis S, Gilard M, Cavalcante JL, Makkar R, Herrmann HC, et al. Transcatheter aortic valve replacement in patients with low-flow, low-gradient aortic stenosis. The TOPAS-TAVI Registry. J Am Coll Cardiol. 2018;71:1297–308.CrossRef
12.
go back to reference Otto CM, Kumbhani DJ, Alexander KP, Calhoon JH, Desai MY, Kaul S, Lee JC, Ruiz CE, Vassileva CM 2017 ACC expert consensus decision pathway for transcatheter aortic valve replacement in the management of adults with aortic stenosis: a report from the American College of Cardiology Task Force on Clinical Expert Consensus Documents. J Am Coll Cardiol 2017;69:1313–1346. Otto CM, Kumbhani DJ, Alexander KP, Calhoon JH, Desai MY, Kaul S, Lee JC, Ruiz CE, Vassileva CM 2017 ACC expert consensus decision pathway for transcatheter aortic valve replacement in the management of adults with aortic stenosis: a report from the American College of Cardiology Task Force on Clinical Expert Consensus Documents. J Am Coll Cardiol 2017;69:1313–1346.
13.
go back to reference • Pibarot P, Hahn RT, Weissman NJ, Monaghan MJ. Assessment of paravalvular regurgitation following TAVR. J Am Coll Cardiol Img. 2015;8:340–60. This paper outlines a 5 class grading scheme for paravalvular aortic regurgitation. Grading is based on assessment of jet appearance from color Doppler and quantitative parameters from spectral Doppler. CrossRef • Pibarot P, Hahn RT, Weissman NJ, Monaghan MJ. Assessment of paravalvular regurgitation following TAVR. J Am Coll Cardiol Img. 2015;8:340–60. This paper outlines a 5 class grading scheme for paravalvular aortic regurgitation. Grading is based on assessment of jet appearance from color Doppler and quantitative parameters from spectral Doppler. CrossRef
14.
go back to reference Reardon MJ, Vieghem NM, Popma JJ, Kleiman NS, Sondergaard L, Mumtaz M, et al. Surgical or transcatheter aortic-valve replacement in intermediate risk patients. N Engl J Med. 2017;376:1321–31.CrossRef Reardon MJ, Vieghem NM, Popma JJ, Kleiman NS, Sondergaard L, Mumtaz M, et al. Surgical or transcatheter aortic-valve replacement in intermediate risk patients. N Engl J Med. 2017;376:1321–31.CrossRef
15.
go back to reference Makkar RR, Fontana G, Jilaihawi H, Chakravarty T, Kofoed KF, DeBacker O, et al. Possible subclinical leaflet thrombosis in bioprosthetic aortic valves. N Engl J Med. 2015;373:2015–24.CrossRef Makkar RR, Fontana G, Jilaihawi H, Chakravarty T, Kofoed KF, DeBacker O, et al. Possible subclinical leaflet thrombosis in bioprosthetic aortic valves. N Engl J Med. 2015;373:2015–24.CrossRef
Metadata
Title
Comprehensive Assessment of Aortic Stenosis in the TAVR Era
Author
Michael J. Malkowski
Publication date
01-11-2018
Publisher
Springer US
Published in
Current Cardiovascular Imaging Reports / Issue 11/2018
Print ISSN: 1941-9066
Electronic ISSN: 1941-9074
DOI
https://doi.org/10.1007/s12410-018-9469-x

Other articles of this Issue 11/2018

Current Cardiovascular Imaging Reports 11/2018 Go to the issue

Cardiac Computed Tomography (M Cheezum and B Chow, Section Editors)

Utility of Cardiac Computed Tomography in Patients with Left Ventricular Assist Devices

Cardiac Computed Tomography (M Cheezum and B Chow, Section Editors)

Coronary CTA for Surveillance of Cardiac Allograft Vasculopathy