Skip to main content
Top
Published in: Reproductive Biology and Endocrinology 1/2011

Open Access 01-12-2011 | Methodology

Comparison of the effect of a CIDR-Select Synch versus a long-term CIDR based AI protocol on reproductive performance in multiparous dairy cows in Swiss dairy farms

Authors: Jürn Rudolph, Rupert M Bruckmaier, Ramanathan Kasimanickam, Adrian Steiner, Marc Kirchhofer, Jürg Hüsler, Gaby Hirsbrunner

Published in: Reproductive Biology and Endocrinology | Issue 1/2011

Login to get access

Abstract

Background

Synchronization programs have become standard in the dairy industry in many countries. In Switzerland, these programs are not routinely used for groups of cows, but predominantly as a therapy for individual problem cows. The objective of this study was to compare the effect of a CIDR-Select Synch and a 12-d CIDR protocol on the pregnancy rate in healthy, multiparous dairy cows in Swiss dairy farms.

Methods

Cows (N = 508) were randomly assigned to CIDR-Select Synch (N = 262) or 12-d CIDR (N = 246) protocols. Cows in the CIDR-Select Synch group received a CIDR and 2.5 ml of buserelin i.m. on d 0. On d 7, the CIDR insert was removed and 5 ml of dinoprost was administered i.m.. Cows in the 12-d CIDR group received the CIDR on d 0 and it was removed on d 12 (the routine CIDR protocol in Swiss dairies). On d 0 a milk sample for progesterone analysis was taken. Cows were inseminated upon observed estrus. Pregnancy was determined at or more than 35 days after artificial insemination. As a first step, the two groups were compared as to indication for treatment, breed, stud book, stall, pasture, and farmer's business using chi square tests or Fisher's exact test. Furthermore, groups were compared as to age, DIM, number of AI's, number of cows per farm, and yearly milk yield per cow using nonparametric ANOVA. A multiple logistic model was used to relate the success of the protocols to all of the available factors; in particular treatment (CIDR-Select Synch/12-d CIDR), milk progesterone value, age, DIM, previous treatment of the uterus, previous gynecological treatment, and number of preceding inseminations.

Results

The pregnancy rate was higher in cows following the CIDR-Select Synch compared to the 12-d CIDR protocol (50.4% vs. 22.4%; P < 0.0001).

Conclusion

The CIDR-Select Synch protocol may be highly recommended for multiparous dairy cows. The reduced time span of the progesterone insert decreased the number of days open, improved the pregnancy rate compared to the 12-d CIDR protocol and the cows did not to have to be handled more often.
Appendix
Available only for authorised users
Literature
3.
go back to reference Busato A, Minder C, Küpfer U: Importance and seasonal pattern of fertility disorders in 80 Swiss dairy farms. Epidemiol sante anim. 1997, 31-32: 5- Busato A, Minder C, Küpfer U: Importance and seasonal pattern of fertility disorders in 80 Swiss dairy farms. Epidemiol sante anim. 1997, 31-32: 5-
4.
go back to reference Garverick HA: Ovarian follicular cysts in dairy cows. J Dairy Sci. 1997, 80: 995-1004. 10.3168/jds.S0022-0302(97)76025-9.CrossRefPubMed Garverick HA: Ovarian follicular cysts in dairy cows. J Dairy Sci. 1997, 80: 995-1004. 10.3168/jds.S0022-0302(97)76025-9.CrossRefPubMed
5.
go back to reference Osawa T, Nakao T, Kimura M, Kaneko K, Takagi H, Moriyoshi M, Kawata K: Fertirelin and buserelin compared by LH release, milk progesterone and subsequent reproductive performance in dairy cows treated for follicular cysts. Theriogenology. 1995, 44: 835-847. 10.1016/0093-691X(95)00269-E.CrossRefPubMed Osawa T, Nakao T, Kimura M, Kaneko K, Takagi H, Moriyoshi M, Kawata K: Fertirelin and buserelin compared by LH release, milk progesterone and subsequent reproductive performance in dairy cows treated for follicular cysts. Theriogenology. 1995, 44: 835-847. 10.1016/0093-691X(95)00269-E.CrossRefPubMed
6.
go back to reference Calder MD, Salfen BE, Bao B, Youngquist RS, Garverick HA: Administration of progesterone to cows with ovarian follicular cysts results in a reduction in mean LH and LH pulse frequency and initiates ovulatory follicular growth. J Anim Sci. 1999, 77: 3037-3042.PubMed Calder MD, Salfen BE, Bao B, Youngquist RS, Garverick HA: Administration of progesterone to cows with ovarian follicular cysts results in a reduction in mean LH and LH pulse frequency and initiates ovulatory follicular growth. J Anim Sci. 1999, 77: 3037-3042.PubMed
7.
go back to reference Tebble JE, O'Donnell MJ, Dobson H: Ultrasound diagnosis and treatment outcome of cystic ovaries in cattle. Vet Rec. 2001, 148: 411-413. 10.1136/vr.148.13.411.CrossRefPubMed Tebble JE, O'Donnell MJ, Dobson H: Ultrasound diagnosis and treatment outcome of cystic ovaries in cattle. Vet Rec. 2001, 148: 411-413. 10.1136/vr.148.13.411.CrossRefPubMed
8.
go back to reference Chebel RC, Santos JE, Cerri RL, Rutigliano HM, Bruno RG: Reproduction in dairy cows following progesterone insert presynchronization and resynchronization protocols. J Dairy Sci. 2006, 89: 4205-4219. 10.3168/jds.S0022-0302(06)72466-3.CrossRefPubMed Chebel RC, Santos JE, Cerri RL, Rutigliano HM, Bruno RG: Reproduction in dairy cows following progesterone insert presynchronization and resynchronization protocols. J Dairy Sci. 2006, 89: 4205-4219. 10.3168/jds.S0022-0302(06)72466-3.CrossRefPubMed
9.
go back to reference Odde KG: A review of synchronization of estrus in postpartum cattle. J Anim Sci. 1990, 68: 817-830.PubMed Odde KG: A review of synchronization of estrus in postpartum cattle. J Anim Sci. 1990, 68: 817-830.PubMed
10.
go back to reference Roche JF: Synchronization of estrous in heifers with implants of progesterone. J Reprod Fertil. 1974, 41: 337-344. 10.1530/jrf.0.0410337.CrossRefPubMed Roche JF: Synchronization of estrous in heifers with implants of progesterone. J Reprod Fertil. 1974, 41: 337-344. 10.1530/jrf.0.0410337.CrossRefPubMed
11.
go back to reference Lane EA, Austin EJ, Crowe MA: Estrous sychronisation in cattle-Current options following the EU regulation restricting use of oestrogenic compounds in food-producing animals: A review. Anim Reprod Sci. 2008, 109: 1-16. 10.1016/j.anireprosci.2008.08.009.CrossRefPubMed Lane EA, Austin EJ, Crowe MA: Estrous sychronisation in cattle-Current options following the EU regulation restricting use of oestrogenic compounds in food-producing animals: A review. Anim Reprod Sci. 2008, 109: 1-16. 10.1016/j.anireprosci.2008.08.009.CrossRefPubMed
12.
go back to reference Adams GP, Jaiswal R, Singh J, Malhi P: Progress in understanding ovarian follicular dynamics in cattle. Theriogenology. 2008, 69: 72-80. 10.1016/j.theriogenology.2007.09.026.CrossRefPubMed Adams GP, Jaiswal R, Singh J, Malhi P: Progress in understanding ovarian follicular dynamics in cattle. Theriogenology. 2008, 69: 72-80. 10.1016/j.theriogenology.2007.09.026.CrossRefPubMed
13.
go back to reference Crane MB, Bartolome J, Melendez P, de Vries A, Risco C, Archbald LF: Comparison of synchronization of ovulation with timed insemination and exogenous progesterone as therapeutic strategies for ovarian cysts in lactating dairy cows. Theriogenology. 2006, 65: 1563-1574. 10.1016/j.theriogenology.2005.09.003.CrossRefPubMed Crane MB, Bartolome J, Melendez P, de Vries A, Risco C, Archbald LF: Comparison of synchronization of ovulation with timed insemination and exogenous progesterone as therapeutic strategies for ovarian cysts in lactating dairy cows. Theriogenology. 2006, 65: 1563-1574. 10.1016/j.theriogenology.2005.09.003.CrossRefPubMed
14.
go back to reference Thatcher WW, Moreira F, Pancarci SM, Bartolome JA, Santos JE: Strategies to optimize reproductive efficiency by regulation of ovarian function. Domest Anim Endocrinol. 2002, 23 (1-2): 243-254. 10.1016/S0739-7240(02)00160-1.CrossRefPubMed Thatcher WW, Moreira F, Pancarci SM, Bartolome JA, Santos JE: Strategies to optimize reproductive efficiency by regulation of ovarian function. Domest Anim Endocrinol. 2002, 23 (1-2): 243-254. 10.1016/S0739-7240(02)00160-1.CrossRefPubMed
15.
go back to reference El-Zarkouny SZ, Cartmill JA, Hensley BA, Stevenson JS: Pregnancy in dairy cows after synchronized ovulation regimens with or without presynchronization and progesterone. J Dairy Sci. 2004, 87: 1024-1037. 10.3168/jds.S0022-0302(04)73248-8.CrossRefPubMed El-Zarkouny SZ, Cartmill JA, Hensley BA, Stevenson JS: Pregnancy in dairy cows after synchronized ovulation regimens with or without presynchronization and progesterone. J Dairy Sci. 2004, 87: 1024-1037. 10.3168/jds.S0022-0302(04)73248-8.CrossRefPubMed
16.
go back to reference Meyer HHD, Güven B, Karg H: Enzymimmuntest (EIA) auf Mikrotiterplatten zur Progesteronbestimmung in Magermilchproben. Wien Tierärztl Mschr. 1986, 73: 86-94. Meyer HHD, Güven B, Karg H: Enzymimmuntest (EIA) auf Mikrotiterplatten zur Progesteronbestimmung in Magermilchproben. Wien Tierärztl Mschr. 1986, 73: 86-94.
17.
go back to reference Chebel RC, Al-Hassan MJ, Fricke PM, Santos JE, Lima JR, Martel CA, Stevenson JS, Garcia R, Ax RL: Supplementation of progesterone via controlled internal drug release inserts during ovulation synchronization protocols in lactating dairy cows. J Dairy Sci. 2010, 93: 922-931. 10.3168/jds.2009-2301.CrossRefPubMed Chebel RC, Al-Hassan MJ, Fricke PM, Santos JE, Lima JR, Martel CA, Stevenson JS, Garcia R, Ax RL: Supplementation of progesterone via controlled internal drug release inserts during ovulation synchronization protocols in lactating dairy cows. J Dairy Sci. 2010, 93: 922-931. 10.3168/jds.2009-2301.CrossRefPubMed
18.
go back to reference Lamb GC, Stevenson JS, Kesler DJ, Gaverick HA, Brown DR, Salfen BE: Inclusion of an intravaginal progesterone insert plus GnRH and prostaglandin F2alpha for ovulation control in postpartum suckled beef cows. J Anim Sci. 2001, 79: 2253-2259.PubMed Lamb GC, Stevenson JS, Kesler DJ, Gaverick HA, Brown DR, Salfen BE: Inclusion of an intravaginal progesterone insert plus GnRH and prostaglandin F2alpha for ovulation control in postpartum suckled beef cows. J Anim Sci. 2001, 79: 2253-2259.PubMed
19.
go back to reference Mihm M, Baguisi A, Boland MP, Roche JF: Association between the duration of dominance of the ovulatory follicle and pregnancy rate in beef heifers. J Reprod Fertil. 1994, 102: 123-130. 10.1530/jrf.0.1020123.CrossRefPubMed Mihm M, Baguisi A, Boland MP, Roche JF: Association between the duration of dominance of the ovulatory follicle and pregnancy rate in beef heifers. J Reprod Fertil. 1994, 102: 123-130. 10.1530/jrf.0.1020123.CrossRefPubMed
20.
go back to reference Twagiramungu H, Guilbault A, Dufour J: Synchronization of follicular waves with a gonadotropin-releasing hormone agonist to increase the precision of estrus in cattle: a review. J Anim Sci. 1995, 73: 3141-3151.PubMed Twagiramungu H, Guilbault A, Dufour J: Synchronization of follicular waves with a gonadotropin-releasing hormone agonist to increase the precision of estrus in cattle: a review. J Anim Sci. 1995, 73: 3141-3151.PubMed
21.
go back to reference Howard JM, Manzo R, Dalton JC, Frago F, Ahmadzadeh A: Conception rates and serum progesterone concentration in dairy cattle administered gonadotrophin releasing hormone 5 days after artificial insemination. Anim Reprod Sci. 2006, 95: 224-233. 10.1016/j.anireprosci.2005.10.010.CrossRefPubMed Howard JM, Manzo R, Dalton JC, Frago F, Ahmadzadeh A: Conception rates and serum progesterone concentration in dairy cattle administered gonadotrophin releasing hormone 5 days after artificial insemination. Anim Reprod Sci. 2006, 95: 224-233. 10.1016/j.anireprosci.2005.10.010.CrossRefPubMed
22.
go back to reference Stevenson JS, Portaluppi MA, Tenhouse DE, Lloyd A, Eborn DR, Kacuba S, DeJarnette JM: Interventions after artificial insemination: conception rates, pregnancy survival, and ovarian responses to gonadotropin-releasing hormone, human chorionic gonadotropin, and progesterone. J Dairy Sci. 2007, 90: 331-340. 10.3168/jds.S0022-0302(07)72634-6.CrossRefPubMed Stevenson JS, Portaluppi MA, Tenhouse DE, Lloyd A, Eborn DR, Kacuba S, DeJarnette JM: Interventions after artificial insemination: conception rates, pregnancy survival, and ovarian responses to gonadotropin-releasing hormone, human chorionic gonadotropin, and progesterone. J Dairy Sci. 2007, 90: 331-340. 10.3168/jds.S0022-0302(07)72634-6.CrossRefPubMed
23.
go back to reference Thuemmel AE, Gwazdauskas FC, Whittier WD, McGilliard ML: Effect of progesterone supplementation in repeat-breeder cattle on conception and plasma progesterone. Endocrinol Invest. 1992, 15: 393-396.CrossRef Thuemmel AE, Gwazdauskas FC, Whittier WD, McGilliard ML: Effect of progesterone supplementation in repeat-breeder cattle on conception and plasma progesterone. Endocrinol Invest. 1992, 15: 393-396.CrossRef
24.
go back to reference Son DS, Choe CY, Cho SR, Choi SH, Kim HJ, Hur TY, Jung YG, Kang HG, Kim IH: A CIDR-based timed embryo transfer protocol increases the pregnancy rate of lactating repeat breeder dairy cows. J Reprod Dev. 2007, 53: 1313-1318. 10.1262/jrd.19066.CrossRefPubMed Son DS, Choe CY, Cho SR, Choi SH, Kim HJ, Hur TY, Jung YG, Kang HG, Kim IH: A CIDR-based timed embryo transfer protocol increases the pregnancy rate of lactating repeat breeder dairy cows. J Reprod Dev. 2007, 53: 1313-1318. 10.1262/jrd.19066.CrossRefPubMed
25.
go back to reference Kim UH, Suh GH, Hur TY, Kang SJ, Kang HG, Park SB, Kim HS, Kim IH: Comparison of two types of CIDR-based timed artificial insemination protocols for repeat breeder dairy cows. J Reprod Dev. 2007, 53: 639-645. 10.1262/jrd.18147.CrossRefPubMed Kim UH, Suh GH, Hur TY, Kang SJ, Kang HG, Park SB, Kim HS, Kim IH: Comparison of two types of CIDR-based timed artificial insemination protocols for repeat breeder dairy cows. J Reprod Dev. 2007, 53: 639-645. 10.1262/jrd.18147.CrossRefPubMed
26.
go back to reference Perry GA, Perry BL: GnRH treatment at artificial insemination in beef cattle fails to increase plasma progesterone concentrations or pregnancy rates. Theriogenology. 2009, 71: 775-779. 10.1016/j.theriogenology.2008.09.050.CrossRefPubMed Perry GA, Perry BL: GnRH treatment at artificial insemination in beef cattle fails to increase plasma progesterone concentrations or pregnancy rates. Theriogenology. 2009, 71: 775-779. 10.1016/j.theriogenology.2008.09.050.CrossRefPubMed
27.
go back to reference Ryan DP, Snijders S, Yaakub H, O'Farrell KJ: An evaluation of estrus synchronization programs in reproductive management of dairy herds. J Anim Sci. 1995, 73: 3687-3695.PubMed Ryan DP, Snijders S, Yaakub H, O'Farrell KJ: An evaluation of estrus synchronization programs in reproductive management of dairy herds. J Anim Sci. 1995, 73: 3687-3695.PubMed
28.
go back to reference Ryan P, Galvin A, O'Farrell J: Comparison of oestrous synchronization regimens for lactating dairy cows. Anim Reprod Sci. 1999, 56: 153-168. 10.1016/S0378-4320(99)00028-7.CrossRefPubMed Ryan P, Galvin A, O'Farrell J: Comparison of oestrous synchronization regimens for lactating dairy cows. Anim Reprod Sci. 1999, 56: 153-168. 10.1016/S0378-4320(99)00028-7.CrossRefPubMed
29.
go back to reference Lucy MC: Reproductive loss in high-producing dairy cattle: Where will it end?. J Dai Sci. 2001, 84: 1277-1293. 10.3168/jds.S0022-0302(01)70158-0.CrossRef Lucy MC: Reproductive loss in high-producing dairy cattle: Where will it end?. J Dai Sci. 2001, 84: 1277-1293. 10.3168/jds.S0022-0302(01)70158-0.CrossRef
30.
go back to reference Stevenson JS, Kobayashi Y, Thompson KE: Reproductive performance of dairy cows in various programmed breeding systems including OvSynch and combinations of Gonadotropin-Releasing Hormone and Prostaglandin F. J Dai Sci. 1999, 82: 505-515. Stevenson JS, Kobayashi Y, Thompson KE: Reproductive performance of dairy cows in various programmed breeding systems including OvSynch and combinations of Gonadotropin-Releasing Hormone and Prostaglandin F. J Dai Sci. 1999, 82: 505-515.
Metadata
Title
Comparison of the effect of a CIDR-Select Synch versus a long-term CIDR based AI protocol on reproductive performance in multiparous dairy cows in Swiss dairy farms
Authors
Jürn Rudolph
Rupert M Bruckmaier
Ramanathan Kasimanickam
Adrian Steiner
Marc Kirchhofer
Jürg Hüsler
Gaby Hirsbrunner
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Reproductive Biology and Endocrinology / Issue 1/2011
Electronic ISSN: 1477-7827
DOI
https://doi.org/10.1186/1477-7827-9-151

Other articles of this Issue 1/2011

Reproductive Biology and Endocrinology 1/2011 Go to the issue