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01-04-2018 | Original Scientific Report

Comparison of Regeneration of Remnant Liver After Hemihepatectomy with or Without the Middle Hepatic Vein

Authors: Yoshihiro Inoue, Yusuke Suzuki, Masato Ota, Kensuke Fujii, Nao Kawaguchi, Tetsunosuke Shimizu, Mitsuhiro Asakuma, Fumitoshi Hirokawa, Michihiro Hayashi, Kazuhisa Uchiyama

Published in: World Journal of Surgery | Issue 4/2018

Abstract

Background

There is no consensus about remnant liver regeneration associated with middle hepatic vein (MHV) resecting.

Methods

Seventy-five patients who underwent hemihepatectomy were retrospectively analysed with respect to remnant liver regeneration. The liver remnant volume (LRV) and each sectional volume were postoperatively measured with multidetector computed tomography at day 7 and months 1, 2, 5, and 12 after the operation.

Results

In right hemihepatectomy cases, the regeneration rate of LRV in the MHV preservation group was significantly higher than that of the MHV resection group at months 5 and 12. In particular, the regeneration rate of remnant segment IV peaked at day 7 and was shrunk after 1 month, and was significant higher in the MHV preservation group. In left hemihepatectomy cases, the regeneration rate of LRV at month 12 was significantly higher in the MHV preservation group. The regeneration rate of the remnant anterior section peaked at 1 month and was shrunk.

Conclusion

In this study, the MHV should be preserved or reconstructed whenever possible during hepatic hemihepatectomy. Hepatic regeneration in the MHV perfusion region becomes poor within 7 days to 1 month after surgery (UMIN000023714).

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Inoue Y, Hayashi M, Komeda K et al (2012) Resection margin with anatomic or nonanatomic hepatectomy for liver metastasis from colorectal cancer. J Gastrointest Surg 16:1171–1180CrossRefPubMed

Uchiyama K, Ueno M, Ozawa S et al (2011) Combined intraoperative use of contrast-enhanced ultrasonography imaging using a sonazoid and fluorescence navigation system with indocyanine green during anatomical hepatectomy. Langenbecks Arch Surg 396:1101–1107CrossRefPubMed

Uchiyama K, Ueno M, Ozawa S et al (2010) Combined use of contrast-enhanced intraoperative ultrasonography and a fluorescence navigation system for identifying hepatic metastases. World J Surg 34:2953–2959. doi:10.1007/s00268-010-0764-1 CrossRefPubMed

Inoue Y, Hayashi M, Hirokawa F et al (2011) Peritoneovenous shunt for intractable ascites due to hepatic lymphorrhea after hepatectomy. World J Gastrointest Surg 3:16–20CrossRefPubMedPubMedCentral

Kim BS, Kim TK, Kim JS et al (2004) Hepatic venous congestion after living donor liver transplantation with right lobe graft: two-phase CT findings. Radiology 232:173–180CrossRefPubMed

Sano K, Makuuchi M, Miki K et al (2002) Evaluation of hepatic venous congestion: proposed indication criteria for hepatic vein reconstruction. Ann Surg 236:241–247CrossRefPubMedPubMedCentral

Shizawa R (2000) Indication of hepatic vein reconstruction after partial hepatic resection based on hepatic vein branch distribution by using three-dimensional computed tomography. Jpn J Gastroenterol Surg 33:572–578CrossRef

Bégin A, Martel G, Lapointe R et al (2014) Accuracy of preoperative automatic measurement of the liver volume by CT-scan combined to a 3D virtual surgical planning software (3DVSP). Surg Endosc 28:3408–3412CrossRefPubMed

Yamanaka J, Saito S, Fujimoto J (2007) Impact of preoperative planning using virtual segmental volumetry on liver resection for hepatocellular carcinoma. World J Surg 31:1249–1255. doi:10.1007/s00268-007-9020-8 CrossRefPubMed

10.

Pugh RN, Murray-Lyon IM, Dawson JL et al (1973) Transection of the oesophagus for bleeding oesophageal varices. Br J Surg 60:646–649CrossRefPubMed

11.

Couinaud C (1986) Surgical anatomy of the liver. Several new aspects. Chirurgie 112:337–342PubMed

12.

Park EA, Lee JM, Kim SH et al (2007) Hepatic venous congestion after right-lobe living-donor liver transplantation: the added value of delayed-phase imaging on CT. J Comput Assist Tomogr 31:181–187CrossRefPubMed

13.

Inoue Y, Hayashi M, Tanaka R et al (2013) Short-term results of laparoscopic versus open liver resection for liver metastasis from colorectal cancer: a comparative study. Am Surg 79:495–501PubMed

14.

Inoue Y, Tanaka R, Komeda K et al (2014) Fluorescence detection of malignant liver tumors using 5-aminolevulinic acid-mediated photodynamic diagnosis: principles, technique, and clinical experience. World J Surg 38:1786–1794. doi:10.1007/s00268-014-2463-9 CrossRefPubMed

15.

Strasberg SM (2005) Nomenclature of hepatic anatomy and resection: a review of the Brisbane 2000 system. J Hepatobiliary Pancreat Surg 12:351–355CrossRefPubMed

16.

Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213CrossRefPubMedPubMedCentral

17.

Clavien PA, Barkun J, de Oliveira ML et al (2009) The Clavien–Dindo classification of surgical complications: five-year experience. Ann Surg 250:187–196CrossRefPubMed

18.

Arroyo V, Gines P, Gerbes AL et al (1996) Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis. International Ascites Club. Hepatology 23:164–176CrossRefPubMed

19.

Kayashima H, Shirabe K, Morita K et al (2013) Liver regeneration and venous collateral formation in the right lobe living-donor remnant: segmental volumetric analysis and three-dimensional visualization. Transplantation 95:353–360CrossRefPubMed

20.

Yan L, Wu H, Chen Z et al (2008) Intrahepatic venous collaterals formation following outflow block in adult-to-adult living donor liver transplantation. J Surg Res 146:172CrossRefPubMed

21.

Ryu M, Cho A (eds) (2009) New liver anatomy: portal segmentation and drainage vein. Springer, Berlin

22.

Scatton O, Plasse M, Dondero F et al (2008) Impact of localized congestion related to venous deprivation after hepatectomy. Surgery 143:483–489CrossRefPubMed

23.

Mu H, Ariizumi S, Katagiri S et al (2014) An extended dysfunctional area in the congestive area of the remnant liver after hemi-hepatectomy with middle hepatic vein resection for liver cancers evaluated on the gadoxetic acid disodium-enhanced magnetic resonance imaging. J Hepatobiliary Pancreat Sci 21:64–71CrossRefPubMed

24.

Sugimoto T, Ku Y, Saitoh Y (1997) Experimental evaluation of preoperative hepatic occlusion for hepatectomy combined with hepatic vein resection. Jpn J Gastroenterol Surg 30:1714–1719CrossRef

25.

Man K, Fan ST, Lo CM et al (2003) Graft injury in relation to graft size in right lobe live donor liver transplantation: a study of hepatic sinusoidal injury in correlation with portal hemodynamics and intragraft gene expression. Ann Surg 237:256–264PubMedPubMedCentral

26.

Lo CM, Liu CL, Fan ST (2003) Portal hyperperfusion injury as the cause of primary nonfunction in a small-for-size liver graft-successful treatment with splenic artery ligation. Liver Transpl 9:626–628CrossRefPubMed

Title: Comparison of Regeneration of Remnant Liver After Hemihepatectomy with or Without the Middle Hepatic Vein
Authors: Yoshihiro Inoue
Yusuke Suzuki
Masato Ota
Kensuke Fujii
Nao Kawaguchi
Tetsunosuke Shimizu
Mitsuhiro Asakuma
Fumitoshi Hirokawa
Michihiro Hayashi
Kazuhisa Uchiyama
Publication date: 01-04-2018
Publisher: Springer International Publishing
Published in: World Journal of Surgery / Issue 4/2018
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-017-4225-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Comparison of Regeneration of Remnant Liver After Hemihepatectomy with or Without the Middle Hepatic Vein

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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