Skip to main content
Top
Published in: Journal of Cardiothoracic Surgery 1/2013

Open Access 01-12-2013 | Research article

Comparison of left ventricular geometry after HeartMate II and HeartWare left ventricular assist device implantation

Authors: Morteza Tavakkoli Hosseini, Aron Frederik Popov, Andre Ruediger Simon, Mohamed Amrani, Toufan Bahrami

Published in: Journal of Cardiothoracic Surgery | Issue 1/2013

Login to get access

Abstract

Background

HeartMate II (HM II) and HeartWare (HW) Left Ventricular Assist Devices have been successfully used in end-stage heart failure patients as a bridge to transplantation, recovery, or decision. We set out to compare their effect in off-loading the left ventricle and its geometry.

Methods

The left ventricular end diastolic (LVEDD) and end systolic (LVESD) diameters were compared between first time HM II (n = 25) and HW implantations (n = 24) before and after the operation at 1, 3, and 6 months. A p value of less than 0.05 was considered as significant.

Results

Post-operative LVEDD and LVESD at 1, 3, and 6 months were significantly reduced in comparison with pre-operative values in both HM II and HW groups. No significant difference was found comparing HM II and HW groups together before and after the operation.

Conclusions

Our study shows that both HM II and HW can significantly reduce the left ventricular systolic and diastolic dimensions and off-load the left ventricle. The miniaturized nature of HW does not affect its performance and it could be as effective as HM II.
Literature
1.
go back to reference Slaughter MS, Pagani FD, Rogers JG, Miller LW, Sun B, Russell SD: Clinical management of continuous-flow left ventricular assist devices in advanced heart failure. J Heart Lung Transpl. 2010, 29: 1-39. 10.1016/j.healun.2009.10.009.CrossRef Slaughter MS, Pagani FD, Rogers JG, Miller LW, Sun B, Russell SD: Clinical management of continuous-flow left ventricular assist devices in advanced heart failure. J Heart Lung Transpl. 2010, 29: 1-39. 10.1016/j.healun.2009.10.009.CrossRef
2.
go back to reference Lahpor JR: State of the art: implantable ventricular assist devices. Curr Opin Organ Transpl. 2009, 14: 554-559. 10.1097/MOT.0b013e3283303750.CrossRef Lahpor JR: State of the art: implantable ventricular assist devices. Curr Opin Organ Transpl. 2009, 14: 554-559. 10.1097/MOT.0b013e3283303750.CrossRef
3.
go back to reference Miller LW, Pagani FD, Russell SD, John R, Boyle AJ, Aaronson KD: Use of a continuous-flow device in patients awaiting heart transplantation. N Engl J Med. 2007, 357: 885-896. 10.1056/NEJMoa067758.CrossRefPubMed Miller LW, Pagani FD, Russell SD, John R, Boyle AJ, Aaronson KD: Use of a continuous-flow device in patients awaiting heart transplantation. N Engl J Med. 2007, 357: 885-896. 10.1056/NEJMoa067758.CrossRefPubMed
4.
go back to reference Goldstein DJ, Zucker M, Arroyo L, Baran D, McCarthy PM, Loebe M: Safety and feasibility trial of the MicroMed DeBakey ventricular assist device as a bridge to transplantation. J Am Coll Cardiol. 2005, 45: 962-963. 10.1016/j.jacc.2004.12.020.CrossRefPubMed Goldstein DJ, Zucker M, Arroyo L, Baran D, McCarthy PM, Loebe M: Safety and feasibility trial of the MicroMed DeBakey ventricular assist device as a bridge to transplantation. J Am Coll Cardiol. 2005, 45: 962-963. 10.1016/j.jacc.2004.12.020.CrossRefPubMed
5.
go back to reference Hetzer R, Weng Y, Potapov EV, Pasic M, Drews T, Jurmann M: First experiences with a novel magnetically suspended axial flow left ventricular assist device. Eur J Cardiothorac Surg. 2004, 25: 964-970. 10.1016/j.ejcts.2004.02.038.CrossRefPubMed Hetzer R, Weng Y, Potapov EV, Pasic M, Drews T, Jurmann M: First experiences with a novel magnetically suspended axial flow left ventricular assist device. Eur J Cardiothorac Surg. 2004, 25: 964-970. 10.1016/j.ejcts.2004.02.038.CrossRefPubMed
6.
go back to reference Macris MP, Myers TJ, Jarvik R, Robinson JL, Fuqua JM, Parnis SM: In vivo evaluation of an intraventricular electric axial flow pump for left ventricular assistance. ASAIO J. 1994, 40: 719-722. 10.1097/00002480-199407000-00092.CrossRef Macris MP, Myers TJ, Jarvik R, Robinson JL, Fuqua JM, Parnis SM: In vivo evaluation of an intraventricular electric axial flow pump for left ventricular assistance. ASAIO J. 1994, 40: 719-722. 10.1097/00002480-199407000-00092.CrossRef
7.
go back to reference Wieselthaler GMO, Driscoll G, Jansz P, Khaghani A, Strueber M, HVAD Clinical Investigators: Initial clinical experience with a novel left ventricular assist device with a magnetically levitated rotor in a multi-institutional trial. J Heart Lung Transplant. 2010, 29: 1218-25. 10.1016/j.healun.2010.05.016.CrossRefPubMed Wieselthaler GMO, Driscoll G, Jansz P, Khaghani A, Strueber M, HVAD Clinical Investigators: Initial clinical experience with a novel left ventricular assist device with a magnetically levitated rotor in a multi-institutional trial. J Heart Lung Transplant. 2010, 29: 1218-25. 10.1016/j.healun.2010.05.016.CrossRefPubMed
8.
go back to reference Strueber M, O’Driscoll G, Jansz P, Khaghani A, Levy WC, Wieselthaler GM: Multicenter evaluation of an intrapericardial left ventricular assist system. J Am Coll Cardiol. 2011, 57: 1375-1382. 10.1016/j.jacc.2010.10.040.CrossRefPubMed Strueber M, O’Driscoll G, Jansz P, Khaghani A, Levy WC, Wieselthaler GM: Multicenter evaluation of an intrapericardial left ventricular assist system. J Am Coll Cardiol. 2011, 57: 1375-1382. 10.1016/j.jacc.2010.10.040.CrossRefPubMed
9.
go back to reference Popov AF, Hosseini MT, Zych B, Mohite P, Hards R, Krueger H, Bahrami T, Amrani M, Simon AR: Clinical experience with HeartWare left ventricular assist device in patients with end-stage heart failure. Ann Thorac Surg. 2012, 93: 810-815. 10.1016/j.athoracsur.2011.11.076.CrossRefPubMed Popov AF, Hosseini MT, Zych B, Mohite P, Hards R, Krueger H, Bahrami T, Amrani M, Simon AR: Clinical experience with HeartWare left ventricular assist device in patients with end-stage heart failure. Ann Thorac Surg. 2012, 93: 810-815. 10.1016/j.athoracsur.2011.11.076.CrossRefPubMed
10.
go back to reference Popov AF, Hosseini MT, Zych B, Simon AR, Bahrami T: HeartWare left ventricular assist device implantation through bilateral anterior thoracotomy. Ann Thorac Surg. 2012, 93: 674-676. 10.1016/j.athoracsur.2011.09.055.CrossRefPubMed Popov AF, Hosseini MT, Zych B, Simon AR, Bahrami T: HeartWare left ventricular assist device implantation through bilateral anterior thoracotomy. Ann Thorac Surg. 2012, 93: 674-676. 10.1016/j.athoracsur.2011.09.055.CrossRefPubMed
11.
go back to reference Birks EJ, George RS, Hedger M, Bahrami T, Wilton P, Bowles CT: Reversal of severe heart failure with a continuous-flow left ventricular assist device and pharmacological therapy: a prospective study. Circulation. 2011, 123: 381-390. 10.1161/CIRCULATIONAHA.109.933960.CrossRefPubMed Birks EJ, George RS, Hedger M, Bahrami T, Wilton P, Bowles CT: Reversal of severe heart failure with a continuous-flow left ventricular assist device and pharmacological therapy: a prospective study. Circulation. 2011, 123: 381-390. 10.1161/CIRCULATIONAHA.109.933960.CrossRefPubMed
12.
go back to reference Weiss RM, Kerber RE, Goerbig-Campbell JL, Davis MK, Cabuay BM, Ashrith G: The impact of prolonged rotary ventricular assist device support upon ventricular geometry and flow kinetics. J Am Soc Echocardiogr. 2011, 24: 149-156. 10.1016/j.echo.2010.10.009.CrossRefPubMed Weiss RM, Kerber RE, Goerbig-Campbell JL, Davis MK, Cabuay BM, Ashrith G: The impact of prolonged rotary ventricular assist device support upon ventricular geometry and flow kinetics. J Am Soc Echocardiogr. 2011, 24: 149-156. 10.1016/j.echo.2010.10.009.CrossRefPubMed
13.
go back to reference Topilsky Y, Oh JK, Shah DK, Boilson BA, Schirger JA, Kushwaha SS: Echocardiographic predictors of adverse outcomes after continuous left ventricular assist device implantation. JACC Cardiovasc Imaging. 2011, 4: 211-222. 10.1016/j.jcmg.2010.10.012.CrossRefPubMed Topilsky Y, Oh JK, Shah DK, Boilson BA, Schirger JA, Kushwaha SS: Echocardiographic predictors of adverse outcomes after continuous left ventricular assist device implantation. JACC Cardiovasc Imaging. 2011, 4: 211-222. 10.1016/j.jcmg.2010.10.012.CrossRefPubMed
14.
go back to reference Maybaum S, Mancini D, Xydas S, Starling RC, Aaronson K, Pagani FD: Cardiac improvement during mechanical circulatory support: a prospective multicenter study of the LVAD working group. Circulation. 2007, 115: 2497-2505. 10.1161/CIRCULATIONAHA.106.633180.CrossRefPubMed Maybaum S, Mancini D, Xydas S, Starling RC, Aaronson K, Pagani FD: Cardiac improvement during mechanical circulatory support: a prospective multicenter study of the LVAD working group. Circulation. 2007, 115: 2497-2505. 10.1161/CIRCULATIONAHA.106.633180.CrossRefPubMed
Metadata
Title
Comparison of left ventricular geometry after HeartMate II and HeartWare left ventricular assist device implantation
Authors
Morteza Tavakkoli Hosseini
Aron Frederik Popov
Andre Ruediger Simon
Mohamed Amrani
Toufan Bahrami
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Journal of Cardiothoracic Surgery / Issue 1/2013
Electronic ISSN: 1749-8090
DOI
https://doi.org/10.1186/1749-8090-8-31

Other articles of this Issue 1/2013

Journal of Cardiothoracic Surgery 1/2013 Go to the issue