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Radiation Oncology
Published in: Radiation Oncology 1/2012

Open Access 01-12-2012 | Research

Comparison of intensity modulated radiotherapy (IMRT) with intensity modulated particle therapy (IMPT) using fixed beams or an ion gantry for the treatment of patients with skull base meningiomas

Authors: Katsura Kosaki, Swantje Ecker, Daniel Habermehl, Stefan Rieken, Oliver Jäkel, Klaus Herfarth, Jürgen Debus, Stephanie E Combs

Published in: Radiation Oncology | Issue 1/2012

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Abstract

Background

To examine the potential improvement in treatment planning for patients with skull base meningioma using IMRT compared to carbon ion or proton beams with and without a gantry.

Methods

Five patients originally treated with photon IMRT were selected for the study. Ion beams were chosen using a horizontal beam or an ion gantry. Intensity controlled raster scanning and the intensity modulated particle therapy mode were used for plan optimization. The evaluation included analysis of dose-volume histograms of the target volumes and organs at risk.

Results

In comparison with carbon and proton beams only with horizontal beams, carbon ion treatment plans could spare the OARs more and concentrated on the target volumes more than proton and photon IMRT treatment plans. Using only a horizontal fixed beam, satisfactory plans could be achieved for skull base tumors.

Conclusion

The results of the case studies showed that using IMPT has the potential to overcome the lack of a gantry for skull base tumors. Carbon ion plans offered slightly better dose distributions than proton plans, but the differences were not clinically significant with established dose prescription concepts.
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Metadata
Title
Comparison of intensity modulated radiotherapy (IMRT) with intensity modulated particle therapy (IMPT) using fixed beams or an ion gantry for the treatment of patients with skull base meningiomas
Authors
Katsura Kosaki
Swantje Ecker
Daniel Habermehl
Stefan Rieken
Oliver Jäkel
Klaus Herfarth
Jürgen Debus
Stephanie E Combs
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Radiation Oncology / Issue 1/2012
Electronic ISSN: 1748-717X
DOI
https://doi.org/10.1186/1748-717X-7-44

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