Published in:
01-04-2015 | Original Article
Comparison of 3D ultrasound and magnetic resonance imaging for microwave ablation in the canine splenomegaly model
Authors:
Lin Sheng, Jialiang Li, Jibing Chen, Ping Liang, Baowei Dong
Published in:
International Journal of Computer Assisted Radiology and Surgery
|
Issue 4/2015
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Abstract
Purpose
Microwave ablation is used for the treatment of hypersplenism. Image guidance and ablation volume assessment is important to ensure that the ablation is successful. The accuracy of 3D ultrasound (US) and magnetic resonance imaging (MRI) in determining the parameters for microwave ablation were compared in a canine splenomegaly model.
Methods
Microwave ablation of the spleen was performed on 13 dogs with congestive splenomegaly. Several combinations of power output and ablation time were used: 60 W for 300 s, 50 W for 360 s and 40 W for 450 s. The ablation zone volume was measured by 3D US and 3D MRI immediately after microwave ablation, and at 1, 2 and 8 weeks thereafter.
Results
Compared with 3D MRI, the ablation zone reconstruction rate was lower with 3D US (92 vs. 100 %). However, there was no significant difference was found in the ablation volume calculated soon after the treatment and 1 week and 2 months later.
Conclusion
3D US may be useful for quantifying the volume of microwave ablation zones in the spleens of experimental animals and appears promising as an alterative modality to MRI for clinical examinations.