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Intensive Care Medicine
Published in: Intensive Care Medicine 6/2005

01-06-2005 | Pediatric Original

Comparison between cerebral tissue oxygenation index measured by near-infrared spectroscopy and venous jugular bulb saturation in children

Authors: Nicole Nagdyman, Thilo Fleck, Stephan Schubert, Peter Ewert, Björn Peters, Peter E. Lange, Hashim Abdul-Khaliq

Published in: Intensive Care Medicine | Issue 6/2005

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Abstract

Objective

To compare the cerebral tissue oxygenation index (TOI) measured by near-infrared spectroscopy (NIRS) with venous oxygen saturation in the jugular bulb (SjO2) during elective cardiac catheterization in children.

Design and setting

Prospective observational clinical study in a catheterization laboratory for pediatric cardiology.

Patients

Sixty children with congenital heart defects admitted to the catheterization laboratory.

Measurements and results

TOI measured noninvasively by NIRS was compared to SjO2 measured in the jugular bulb during cardiac catheterization. Patients were divided into two groups regarding body weight: below (n=29) and above 10 kg (n=31). Linear regression analysis and Pearson’s correlation coefficient were calculated. Bland-Altman analysis, sensitivity, and specificity calculation for spatially resolved near-infrared spectroscopy with a cutoff level of 60% were performed. Simultaneously measured values for SjO2 (67.3±9.8%, 40–84.1%) and TOI (65.7±7.2%, 39–80%) showed a significant correlation; the correlation in children weighing under 10 kg was stronger in children weighing over 10 kg. Bland-Altman analysis showed a mean bias of −1.8% with limits of agreement between 11.7% and −15.3% for all children. Sensitivity and specificity of the SRS method were 46% and 91%, respectively, for all children and 53% and 83% respectively in infants weighing under 10 kg.

Conclusions

The results demonstrate that despite a significant correlation, sensitivity of spatially resolved spectroscopy is poor, and it is questionable whether TOI can be used reliably to detect low SjO2.
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Metadata
Title
Comparison between cerebral tissue oxygenation index measured by near-infrared spectroscopy and venous jugular bulb saturation in children
Authors
Nicole Nagdyman
Thilo Fleck
Stephan Schubert
Peter Ewert
Björn Peters
Peter E. Lange
Hashim Abdul-Khaliq
Publication date
01-06-2005
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 6/2005
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-005-2618-0

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