Skip to main content
Top
Published in: Journal of Orthopaedic Surgery and Research 1/2018

Open Access 01-12-2018 | Research article

Comparing the costs and outcomes of an integrated twin compression screw (ITCS) nail with standard of care using a single lag screw or a single helical blade cephalomedullary nail in patients with intertrochanteric hip fractures

Authors: Leo M. Nherera, Paul Trueman, Alan Horner, Alan J. Johnstone, Tracy J. Watson, Francis A. Fatoye

Published in: Journal of Orthopaedic Surgery and Research | Issue 1/2018

Login to get access

Abstract

Background

Surgical treatment is the optimal strategy for managing intertrochanteric fractures as it allows for early rehabilitation and functional recovery. The purpose of the study was to assess the cost-effectiveness of commonly used cephalomedullary nails for the treatment of unstable intertrochanteric hip fractures.

Methods

A decision analytic model was developed from a US payer’s perspective using clinical data from a pairwise meta-analysis of randomised controlled trials (RCTs) and comparative observational studies comparing the integrated twin compression screw (ITCS) nail versus two single-screw or blade cephalomedullary nails [single lag screw (SLS) nail and single helical blade (SHB) nail]. The model considered a cohort of 1000 patients with a mean age of 76, as reported in the clinical studies over a 1-year time period. Cost data was obtained from the Center for Medicare and Medicaid Services website and published literature and adjusted for inflation. One-way and probabilistic sensitivity analyses were conducted to assess the effect of uncertainty in model parameters on model conclusions.

Results

The model estimated 0.546 quality-adjusted life years (QALYs) and 0.78 complications avoided by using the ITCS nail and 0.455 QALYs and 0.67 complications avoided for the standard of care, using SLS or SHB nails. The cost per patient was $34,336 for patients treated with an ITCS nail and $37,036 for patients treated with the standard of care respectively, resulting in a cost saving of $2700 in favour of the ITCS nail. More savings were observed when the ITCS nail was compared to the SHB ($3280 per patient) and SLS ($1652 per patient). The findings were robust to a range of both one-way and the probabilistic sensitivity analyses.

Conclusion

In conclusion, the ITCS nail can be considered a cost saving intervention in patients undergoing intertrochanteric fracture fixation with an intramedullary device. Clinicians and policy makers should be encouraged to adopt healthcare technologies such as ITCS that will help them to provide quality healthcare despite falling budgets.
Literature
3.
go back to reference Ruecker AH, Rupprecht M, Gruber M, Gebauer M, Barvencik F, Briem D, et al. The treatment of intertrochanteric fractures: results using an cephalomedullary nail with integrated cephalocervical screws and linear compression. J Orthop Trauma. 2009;23:22–30.CrossRefPubMed Ruecker AH, Rupprecht M, Gruber M, Gebauer M, Barvencik F, Briem D, et al. The treatment of intertrochanteric fractures: results using an cephalomedullary nail with integrated cephalocervical screws and linear compression. J Orthop Trauma. 2009;23:22–30.CrossRefPubMed
6.
go back to reference Burge R, et al. Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025. J Bone Miner Res. 2007;22(3):465–75.CrossRefPubMed Burge R, et al. Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025. J Bone Miner Res. 2007;22(3):465–75.CrossRefPubMed
9.
go back to reference Matre K, et al. Cephalomedullary nails result in more reoperations than sliding hip screws in two-part intertrochanteric fractures. Clin Orthop Relat Res. 2013;471(4):1379–86.CrossRefPubMed Matre K, et al. Cephalomedullary nails result in more reoperations than sliding hip screws in two-part intertrochanteric fractures. Clin Orthop Relat Res. 2013;471(4):1379–86.CrossRefPubMed
10.
go back to reference Matre K, et al. Sliding hip screw versus IM nail in reverse oblique trochanteric and subtrochanteric fractures. A study of 2716 patients in the Norwegian Hip Fracture Register. Injury. 2013;44(6):735–42.CrossRefPubMed Matre K, et al. Sliding hip screw versus IM nail in reverse oblique trochanteric and subtrochanteric fractures. A study of 2716 patients in the Norwegian Hip Fracture Register. Injury. 2013;44(6):735–42.CrossRefPubMed
11.
go back to reference Matre K, et al. TRIGEN INTERTAN cephalomedullary nail versus sliding hip screw: a prospective, randomized multicenter study on pain, function, and complications in 684 patients with an intertrochanteric or subtrochanteric fracture and one year of follow-up. J Bone Joint Surg Am. 2013;95(3):200–8.CrossRefPubMed Matre K, et al. TRIGEN INTERTAN cephalomedullary nail versus sliding hip screw: a prospective, randomized multicenter study on pain, function, and complications in 684 patients with an intertrochanteric or subtrochanteric fracture and one year of follow-up. J Bone Joint Surg Am. 2013;95(3):200–8.CrossRefPubMed
13.
go back to reference Nherera L, Trueman P, Horner A, Watson TJ, Johnstone AJ. Comparison of a twin interlocking derotation and compression screw cephalomedullary nail (InterTAN) with a single screw derotation cephalomedullary nail (proximal femoral nail antirotation): a systematic review and meta-analysis for intertrochanteric fractures. J Orthop Surg Res. 2018. https:// doi.org/10.1186/s13018-018-0749-6. Nherera L, Trueman P, Horner A, Watson TJ, Johnstone AJ. Comparison of a twin interlocking derotation and compression screw cephalomedullary nail (InterTAN) with a single screw derotation cephalomedullary nail (proximal femoral nail antirotation): a systematic review and meta-analysis for intertrochanteric fractures. J Orthop Surg Res. 2018. https://​ doi.​org/​10.​1186/​s13018-018-0749-6.
14.
go back to reference Berger-Groch J, Rupprecht M, Schoepper S, Schroeder M, Rueger JM, Hoffmann M. Five-year outcome analysis of intertrochanteric femur fractures: a prospective randomized trial comparing a 2-screw and a single-screw cephalomedullary nail. J Orthop Trauma. 2016;30:483–8.CrossRefPubMed Berger-Groch J, Rupprecht M, Schoepper S, Schroeder M, Rueger JM, Hoffmann M. Five-year outcome analysis of intertrochanteric femur fractures: a prospective randomized trial comparing a 2-screw and a single-screw cephalomedullary nail. J Orthop Trauma. 2016;30:483–8.CrossRefPubMed
15.
go back to reference Su H, Sun K, Wang X. A randomized prospective comparison of Intertan and Gamma3 for treating unstable intertrochanteric fractures. Int J Clin Exp Med. 2016;9(5):8640–7. Su H, Sun K, Wang X. A randomized prospective comparison of Intertan and Gamma3 for treating unstable intertrochanteric fractures. Int J Clin Exp Med. 2016;9(5):8640–7.
16.
go back to reference Wu D, Ren G, Peng C, Zheng X, Mao F, Zhang Y. InterTan nail versus Gamma3 nail for cephalomedullary nailing of unstable trochanteric fractures. Diagn Pathol. 2014;9:191.CrossRefPubMedPubMedCentral Wu D, Ren G, Peng C, Zheng X, Mao F, Zhang Y. InterTan nail versus Gamma3 nail for cephalomedullary nailing of unstable trochanteric fractures. Diagn Pathol. 2014;9:191.CrossRefPubMedPubMedCentral
18.
go back to reference Fryback DG, Dunham NC, Palta M, et al. US norms for six generic health related quality-of-life indexes from the National Health Measurement Study. Med Care. 2007;45(12):1162–70.CrossRefPubMedPubMedCentral Fryback DG, Dunham NC, Palta M, et al. US norms for six generic health related quality-of-life indexes from the National Health Measurement Study. Med Care. 2007;45(12):1162–70.CrossRefPubMedPubMedCentral
19.
go back to reference Zhang S, Zhang K, Jia Y, Yu B, Feng W. InterTan nail versus Proximal Femoral Nail antirotation-Asia in the treatment of unstable trochanteric fractures. Orthopedics. 2013;36(3):e288–94.CrossRefPubMed Zhang S, Zhang K, Jia Y, Yu B, Feng W. InterTan nail versus Proximal Femoral Nail antirotation-Asia in the treatment of unstable trochanteric fractures. Orthopedics. 2013;36(3):e288–94.CrossRefPubMed
20.
go back to reference Seyhan M, Turkmen I, Unay K, Ozkut AT. Do PFNA nails and Intertan nails both have the same effects in the treatment of trochanteric fractures? A prospective clinical study. J Orthop Sci. 2015;20(6):1053–61.CrossRefPubMed Seyhan M, Turkmen I, Unay K, Ozkut AT. Do PFNA nails and Intertan nails both have the same effects in the treatment of trochanteric fractures? A prospective clinical study. J Orthop Sci. 2015;20(6):1053–61.CrossRefPubMed
22.
go back to reference Zehir S, Şahin E, Zehir R. Comparison of clinical outcomes with three different intramedullary nailing nails in the treatment of unstable trochanteric fractures. Ulus Travma Acil Cerrahi Derg. 2015;21(6):469–76.PubMed Zehir S, Şahin E, Zehir R. Comparison of clinical outcomes with three different intramedullary nailing nails in the treatment of unstable trochanteric fractures. Ulus Travma Acil Cerrahi Derg. 2015;21(6):469–76.PubMed
23.
go back to reference Zhang H, Zeng X, Zhang N, Zeng D, Xu P, Zhang L, Chen D, Yu W, Zhang X. INTERTAN nail versus proximal femoral nail antirotation-Asia for intertrochanteric femur fractures in elderly patients with primary osteoporosis. J Int Med Res. 2017. https://doi.org/10.1177/0300060517710584. Zhang H, Zeng X, Zhang N, Zeng D, Xu P, Zhang L, Chen D, Yu W, Zhang X. INTERTAN nail versus proximal femoral nail antirotation-Asia for intertrochanteric femur fractures in elderly patients with primary osteoporosis. J Int Med Res. 2017. https://​doi.​org/​10.​1177/​0300060517710584​.
24.
go back to reference Zhang H, Zhu X, Pei G, Zeng X, Zhang N, Xu P, Chen D, Yu W, Zhang X. A retrospective analysis of the InterTan nail and proximal femoral nail anti-rotation in the treatment of intertrochanteric fractures in elderly patients with osteoporosis: a minimum follow-up of 3 years. Orthop Surg Res. 2017. https://doi.org/10.1186/s13018-017-0648-2. Zhang H, Zhu X, Pei G, Zeng X, Zhang N, Xu P, Chen D, Yu W, Zhang X. A retrospective analysis of the InterTan nail and proximal femoral nail anti-rotation in the treatment of intertrochanteric fractures in elderly patients with osteoporosis: a minimum follow-up of 3 years. Orthop Surg Res. 2017. https://​doi.​org/​10.​1186/​s13018-017-0648-2.
Metadata
Title
Comparing the costs and outcomes of an integrated twin compression screw (ITCS) nail with standard of care using a single lag screw or a single helical blade cephalomedullary nail in patients with intertrochanteric hip fractures
Authors
Leo M. Nherera
Paul Trueman
Alan Horner
Alan J. Johnstone
Tracy J. Watson
Francis A. Fatoye
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Journal of Orthopaedic Surgery and Research / Issue 1/2018
Electronic ISSN: 1749-799X
DOI
https://doi.org/10.1186/s13018-018-0923-x

Other articles of this Issue 1/2018

Journal of Orthopaedic Surgery and Research 1/2018 Go to the issue