Skip to main content
Top
Published in: Comparative Clinical Pathology 5/2012

01-10-2012 | Original Article

Comparative biochemical studies on natural Trypanosoma evansi infection in she-camels

Authors: Gaber A. Megahed, Mahmoud R. Abd Ellah, Ahmed Abdel-Rady

Published in: Comparative Clinical Pathology | Issue 5/2012

Login to get access

Abstract

The biochemical changes associating Trypanosoma evansi infection in pregnant and non-pregnant camels were investigated. Based on pregnancy diagnosis and serological findings, camels were classified into four groups as non-pregnant healthy camels (N = 6), non-pregnant camels infected with T. evansi (N = 6), pregnant healthy camels (N = 6), and pregnant camels infected with Trypanosoma evansi (N = 8). The results revealed significant decreases (p < 0.05) in serum total proteins, albumin and globulins levels, and significant increases (p < 0.05) in serum total cholesterol and blood urea nitrogen (BUN) levels in pregnant camels infected with T. evansi compared with healthy pregnant camel. On the other hand, there were hyperproteinemia and hyperglobulinemia in healthy pregnant camel compared with non-pregnant camel. It could be concluded that the biochemical changes associating T. evansi infection in pregnant camels are hypoproteinemia, hypoalbuminemia, and hypoglobulinemia and increased serum total cholesterol and BUN levels.
Literature
go back to reference Black S, Vanderweed V (1989) Serum lipoproteins are required for multiplication of Trypanosoma brucei brucei under axenic culture conditions. Mol Biochem Parasitol 37:65–72PubMedCrossRef Black S, Vanderweed V (1989) Serum lipoproteins are required for multiplication of Trypanosoma brucei brucei under axenic culture conditions. Mol Biochem Parasitol 37:65–72PubMedCrossRef
go back to reference Coles EH (1986) Veterinary clinical pathology, 4th edn. Saunders Comp, Philadelphia Coles EH (1986) Veterinary clinical pathology, 4th edn. Saunders Comp, Philadelphia
go back to reference Derakhshanfar A, Mozaffari AA, Mohaghegh Zadeh A (2010) An outbreak of Trypanosomiasis (Surra) in Camels in the Southern Fars Province of Iran: clinical, hematological and pathological findings. Res J Parasitol 5:23–26CrossRef Derakhshanfar A, Mozaffari AA, Mohaghegh Zadeh A (2010) An outbreak of Trypanosomiasis (Surra) in Camels in the Southern Fars Province of Iran: clinical, hematological and pathological findings. Res J Parasitol 5:23–26CrossRef
go back to reference Diall O, Bajyana Songa E, Magnus E, Kouyate B, Diallo B, Van Meirvenne N, Hamers R (1994) Evaluation of direct serological card agglutination test in the diagnosis of camel trypanosomosis due to Trypanosoma evansi. Rev Sci tech Off Int Epiz 13(3):793–800 Diall O, Bajyana Songa E, Magnus E, Kouyate B, Diallo B, Van Meirvenne N, Hamers R (1994) Evaluation of direct serological card agglutination test in the diagnosis of camel trypanosomosis due to Trypanosoma evansi. Rev Sci tech Off Int Epiz 13(3):793–800
go back to reference Egbe-Nwiyi TN, Chaudry SUR (1994) Trypanosomiasis: prevalence and pathology of camel of arid zone of north eastern Nigeria. Trop Vet 20:30–34 Egbe-Nwiyi TN, Chaudry SUR (1994) Trypanosomiasis: prevalence and pathology of camel of arid zone of north eastern Nigeria. Trop Vet 20:30–34
go back to reference Eltohamy MM, Salama A, Yousef AA (1986) Blood glucose in relation to the reproductive state in she-camel (Camelus dromedaries). Beitr Trop Landwirtsch Veterinärmed 24(4):425–430PubMed Eltohamy MM, Salama A, Yousef AA (1986) Blood glucose in relation to the reproductive state in she-camel (Camelus dromedaries). Beitr Trop Landwirtsch Veterinärmed 24(4):425–430PubMed
go back to reference Enwezor FNC, Sackey AKB (2005) Camel trypanosomosis: a review. Vet Arch 75:439–452 Enwezor FNC, Sackey AKB (2005) Camel trypanosomosis: a review. Vet Arch 75:439–452
go back to reference Esievo KAN, Saror DI (1991) Immunochemistry and immunopathology of animal trypanosomiasis. Vet Bull 61:765–777 Esievo KAN, Saror DI (1991) Immunochemistry and immunopathology of animal trypanosomiasis. Vet Bull 61:765–777
go back to reference Green HP, Portela MPM, St Jean EN, Lugli EB, Raper J (2003) Evidence for a Trypanosoma brucei lipoprotein scavenger receptor. J Biol Chem 278:422–427PubMedCrossRef Green HP, Portela MPM, St Jean EN, Lugli EB, Raper J (2003) Evidence for a Trypanosoma brucei lipoprotein scavenger receptor. J Biol Chem 278:422–427PubMedCrossRef
go back to reference Gutierrez C, Juan A, Corbera MC, Juste DF, Morales I (2006) Clinical, hematological, and biochemical findings in an outbreak of abortion and neonatal mortality associated with Trypanosoma evansi infection in Dromedary Camels. Ann N Y Acad Sci 1081:325–327PubMedCrossRef Gutierrez C, Juan A, Corbera MC, Juste DF, Morales I (2006) Clinical, hematological, and biochemical findings in an outbreak of abortion and neonatal mortality associated with Trypanosoma evansi infection in Dromedary Camels. Ann N Y Acad Sci 1081:325–327PubMedCrossRef
go back to reference Higgins AJ (1983) Observations on the Arabian camel (Camelus dromedaries) and their control. Vet Bull 53:1089–1099 Higgins AJ (1983) Observations on the Arabian camel (Camelus dromedaries) and their control. Vet Bull 53:1089–1099
go back to reference Jatkar PR, Ghosal AK, Singh M (1973) Pathogenesis of anaemia in Trypanosoma evansi infection. III. Studies on serum proteins (in camel). Indian Vet J 50(7):634–636 Jatkar PR, Ghosal AK, Singh M (1973) Pathogenesis of anaemia in Trypanosoma evansi infection. III. Studies on serum proteins (in camel). Indian Vet J 50(7):634–636
go back to reference Logan-Henfrey LL, Gardiner PR, Mahmoud MM (1992) In: Kreier JP, Baker JR (eds) Parasitic protozoa, 2. Academic, San Diego, pp 157–275 Logan-Henfrey LL, Gardiner PR, Mahmoud MM (1992) In: Kreier JP, Baker JR (eds) Parasitic protozoa, 2. Academic, San Diego, pp 157–275
go back to reference Murray M, Dexter TM (1988) Anaemia in bovine African trypanosomiasis. Acta Trop 45:389–432PubMed Murray M, Dexter TM (1988) Anaemia in bovine African trypanosomiasis. Acta Trop 45:389–432PubMed
go back to reference Ngerenwa JJ, Gathumbi P, Mutiga ER, Agumba GJ (1993) Pathogenesis of Trypanosoma (brucei) evansi in small east African goats. Res Vet Sci 54:283–289CrossRef Ngerenwa JJ, Gathumbi P, Mutiga ER, Agumba GJ (1993) Pathogenesis of Trypanosoma (brucei) evansi in small east African goats. Res Vet Sci 54:283–289CrossRef
go back to reference Nok AJ, Nock AH, Bonire JJ (2003) The cholesterol pathway of Trypanosoma congolense could be a target for triphenylsiliconsalicylate inhibition. Appl Organomet Chem 17:17–22CrossRef Nok AJ, Nock AH, Bonire JJ (2003) The cholesterol pathway of Trypanosoma congolense could be a target for triphenylsiliconsalicylate inhibition. Appl Organomet Chem 17:17–22CrossRef
go back to reference Olaho-Mukani W, Nyangao JMN, Ouma JO (1996) Comparison of suratex, parasite detection and antigen-ELISA for the evaluation of treatment efficacy and diagnosis of surra in dromedary camels. J Camel Parasitol Res 3:1–5 Olaho-Mukani W, Nyangao JMN, Ouma JO (1996) Comparison of suratex, parasite detection and antigen-ELISA for the evaluation of treatment efficacy and diagnosis of surra in dromedary camels. J Camel Parasitol Res 3:1–5
go back to reference Pacholek X, Gamatic D, Franekm SG, Tibayrene R (2001) Prevalence of Trypanosoma evansi trypanosomiasis in young camels in west Niger. Rev Élev Méd Vét Pays Trop 44:177–182 Pacholek X, Gamatic D, Franekm SG, Tibayrene R (2001) Prevalence of Trypanosoma evansi trypanosomiasis in young camels in west Niger. Rev Élev Méd Vét Pays Trop 44:177–182
go back to reference Reid SA (2002) Trypanosoma evansi control and containment in Australia. Trends Parasitol 182:19–224 Reid SA (2002) Trypanosoma evansi control and containment in Australia. Trends Parasitol 182:19–224
go back to reference Schwartz HJ, Dioli M (1992) The one-humped camel in Eastern Africa: a pictorial guide to diseases, health care and management. Verlag Josef Margraf, P.O. Box 105, pp 1–10 Schwartz HJ, Dioli M (1992) The one-humped camel in Eastern Africa: a pictorial guide to diseases, health care and management. Verlag Josef Margraf, P.O. Box 105, pp 1–10
go back to reference Woo PTK (1970) The haematocrit centrifugation technique for the diagnosis of African trypanosomiasis. Acta Trop 27:384–386PubMed Woo PTK (1970) The haematocrit centrifugation technique for the diagnosis of African trypanosomiasis. Acta Trop 27:384–386PubMed
go back to reference Zweygarth E, Sabwa C, Röttche D (1984) Serodiagnosis of trypanosomiasis in dromedary camels using a card agglutination test set (TESTRYP® CATT). Ann Soc Belge Méd Trop 64:309–313 Zweygarth E, Sabwa C, Röttche D (1984) Serodiagnosis of trypanosomiasis in dromedary camels using a card agglutination test set (TESTRYP® CATT). Ann Soc Belge Méd Trop 64:309–313
Metadata
Title
Comparative biochemical studies on natural Trypanosoma evansi infection in she-camels
Authors
Gaber A. Megahed
Mahmoud R. Abd Ellah
Ahmed Abdel-Rady
Publication date
01-10-2012
Publisher
Springer-Verlag
Published in
Comparative Clinical Pathology / Issue 5/2012
Print ISSN: 1618-5641
Electronic ISSN: 1618-565X
DOI
https://doi.org/10.1007/s00580-011-1243-2

Other articles of this Issue 5/2012

Comparative Clinical Pathology 5/2012 Go to the issue