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Virology Journal
Published in: Virology Journal 1/2007

Open Access 01-12-2007 | Research

Common Genotypes of Hepatitis B virus prevalent in Injecting drug abusers (addicts) of North West Frontier Province of Pakistan

Authors: Muhammad Masroor Alam, Sohail Zahoor Zaidi, Shehzad Shaukat, Salmaan Sharif, Mehar Angez, Asif Naeem, Shamim Saleha, Javed Aslam Butt, Salman Akbar Malik

Published in: Virology Journal | Issue 1/2007

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Abstract

Background

The epidemiological significance of Hepatitis B virus genotypes has been well established and becoming an essential concern day by day however, much little is known about the mixed infection with more than one Hepatitis B virus genotypes and their clinical relevance.

Methods

Intravenous drug abusers are considered as a major risk group for the acquisition and transmission of blood borne infections like hepatitis B, however, in Pakistan, no such data has ever been reported about the epidemiology of HBV and its genotypes in Injecting Drug Users. 250 individuals were analyzed for hepatitis B virus genotypes after prior screening with serological assay for the detection of HBsAg.

Results

56 (22.4%) individuals were found positive on ELSIA for HBsAg. The genotype distribution was found to be as: genotype D, 62.5%; genotype A, 8.92% while 28.57% individuals were found to be infected with a mixture of genotype A and D.

Conclusion

There is an urgent need of the time to develop public health care policies with special emphasis towards the control of HBV transmission through high risk groups especially Injecting Drug Users.
Appendix
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Metadata
Title
Common Genotypes of Hepatitis B virus prevalent in Injecting drug abusers (addicts) of North West Frontier Province of Pakistan
Authors
Muhammad Masroor Alam
Sohail Zahoor Zaidi
Shehzad Shaukat
Salmaan Sharif
Mehar Angez
Asif Naeem
Shamim Saleha
Javed Aslam Butt
Salman Akbar Malik
Publication date
01-12-2007
Publisher
BioMed Central
Published in
Virology Journal / Issue 1/2007
Electronic ISSN: 1743-422X
DOI
https://doi.org/10.1186/1743-422X-4-63

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