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Intensive Care Medicine
Published in: Intensive Care Medicine 10/2008

01-10-2008 | Correspondence

Comment on “Impact of recent intravenous chemotherapy on outcome in severe sepsis and septic shock patients with haematological malignancies” by Vandijck et al.

Authors: Sascha Meyer, Ludwig Gortner, Sven Gottschling

Published in: Intensive Care Medicine | Issue 10/2008

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Excerpt

Dear Sir: We read with great interest the study by Vandijck et al., which demonstrated promising survival rates in adult cancer patients referred to the ICU with severe sepsis and septic shock [1]. Interestingly, in their study the administration of recent chemotherapy was not associated with an increased risk of death. This is contrast to ours and previous studies in pediatric oncology patients who required admission to a PICU [2, 3]. The most common indications for intensive care treatment in pediatric oncology patients are severe sepsis, septic shock, respiratory and cardio-circulatory failure, and neurologic complications [2, 4]. …
Literature
1.
Vandijck DM, Benoit DD, Depuydt PO, Offner FC, Van Tilborgh AK, Nollet J, Steel E, Noens LA, Decruyenaere JM (2008) Impact of recent intravenous chemotherapy on outcome in severe sepsis and septic shock patients with haematological malignancies. Intensive Care Med 34:847–855PubMedCrossRef
2.
Meyer S, Gottschling S, Biran T, Georg T, Ehlayil K, Graf N, Gortner L (2005) Assessing the risk of mortality in paediatric cancer patients admitted to the paediatric intensive care unit: a novel risk score? Eur J Pediatr 164:563–567PubMedCrossRef
3.
Schneider DT, Lemburg P, Sprock I, Heying R, Gobel R, Nurnberger W (2000) Introduction of the oncological pediatric risk of mortality score (O-PRISM) for ICU support following stem cell transplantation in children. Bone Marrow Transplant 25:1079–1086PubMedCrossRef
4.
Heying R, Schneider DT, Korholz D, Stannigel H, Lemburg P, Gobel U (2001) Efficacy and outcome of intensive care in pediatric oncologic patients. Crit Care Med 29:2276–2280PubMedCrossRef
5.
Ben Abraham R, Toren A, Ono N, Weinbroum AA, Vardi A, Barzilay Z, Paret G (2002) Predictors of outcome in the pediatric intensive care units of children with malignancies. J Pediatr Hematol Oncol 24:23–26PubMedCrossRef
Metadata
Title
Comment on “Impact of recent intravenous chemotherapy on outcome in severe sepsis and septic shock patients with haematological malignancies” by Vandijck et al.
Authors
Sascha Meyer
Ludwig Gortner
Sven Gottschling
Publication date
01-10-2008
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 10/2008
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-008-1222-5

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