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Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

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Open Access 01-12-2019 | Letter to the Editor

Comment on epinephrine during resuscitation of traumatic cardiac arrest and increased mortality: a post hoc analysis of prospective observational study

Authors: Makoto Aoki, Toshikazu Abe

Published in: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine | Issue 1/2019

Abstract

The aim of this Letter to the Editor was to report some important biases in a recently published Article. We agreed with the notion by Yamamoto et al. that the effects of epinephrine regarding was limited without hemostasis, however, this study had major limitations such as no information on etiology of traumatic cardiac arrest (hemorrhagic or on non-hemorrhagic) and on hemostatic treatment. The results of this study should be interpreted with caution and further analysis is necessary. Finally, we commented on the necessity of future study regarding another vasopressor (ie; vasopressin) on traumatic cardiac arrest based on current evidence.

Yamamoto R, Suzuki M, Hayashida K, Yoshizawa J, Sakurai A, Kitamura N, et al. Epinephrine during resuscitation of traumatic cardiac arrest and increased mortality: a post hoc analysis of prospective observational study. Scand J Trauma Resusc Emerg Med. 2019;27(1):74.CrossRef

Aoki M, Abe T, Oshima K. Association of prehospital epinephrine administration with survival among patients with traumatic cardiac arrest caused by traffic collisions. Sci Rep. 2019;9(1):9922.CrossRef

Lin YR, Wu MH, Chen TY, Syue YJ, Yang MC, Lee TH, et al. Time to epinephrine treatment is associated with the risk of mortality in children who achieve sustained ROSC after traumatic out-of-hospital cardiac arrest. Crit Care. 2019;23(1):101.CrossRef

Sims CA, Holena D, Kim P, Pascual J, Smith B, Martin N, et al. Effect of low-dose supplementation of arginine vasopressin on need for blood product transfusions in patients with trauma and hemorrhagic shock: a randomized clinical trial. JAMA Surg. 2019. https://doi.org/10.1001/jamasurg.2019.2884.

Title: Comment on epinephrine during resuscitation of traumatic cardiac arrest and increased mortality: a post hoc analysis of prospective observational study
Authors: Makoto Aoki
Toshikazu Abe
Publication date: 01-12-2019
Publisher: BioMed Central
Published in: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine / Issue 1/2019
Electronic ISSN: 1757-7241
DOI: https://doi.org/10.1186/s13049-019-0686-3

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Comment on epinephrine during resuscitation of traumatic cardiac arrest and increased mortality: a post hoc analysis of prospective observational study

Abstract

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