Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Osteoporosis International
Published in: Osteoporosis International 12/2012

01-12-2012 | Letter to the Editor

Comment on Compston: Pathophysiology of atypical femoral fractures and osteonecrosis of the jaw

Authors: K. Michaëlsson, J. Schilcher, P. Aspenberg

Published in: Osteoporosis International | Issue 12/2012

Login to get access

Excerpt

In the review on atypical subtrochanteric fractures and ONJ [1], Professor Compston concludes that bisphosphonates “whilst not a prerequisite for the development of atypical femoral fractures, may contribute to their development in some cases.” Although an excellent overview, we think this conclusion is an understatement. …
Literature
1.
2.
Schilcher J, Michaelsson K, Aspenberg P (2011) Bisphosphonate use and atypical fractures of the femoral shaft. N Engl J Med 364:1728–1737PubMedCrossRef
3.
Alberg AJ, Ford JG, Samet JM (2007) Epidemiology of lung cancer: ACCP evidence-based clinical practice guidelines (2nd edition). Chest 132:29S–55SPubMedCrossRef
4.
Rothman KJ, Greenland S (2005) Causation and causal inference in epidemiology. Am J Public Health 95(Suppl 1):S144–S150PubMedCrossRef
5.
Rizzoli R, Akesson K, Bouxsein M et al (2011) Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report. Osteoporos Int 22:373–390PubMedCrossRef
6.
Ringe JD, Doherty JG (2010) Absolute risk reduction in osteoporosis: assessing treatment efficacy by number needed to treat. Rheumatol Int 30:863–869PubMedCrossRef
7.
Aspenberg P, Schilcher J, Fahlgren A (2010) Histology of an undisplaced femoral fatigue fracture in association with bisphosphonate treatment. Frozen bone with remodelling at the crack. Acta Orthop 81:460–462PubMedCrossRef
Metadata
Title
Comment on Compston: Pathophysiology of atypical femoral fractures and osteonecrosis of the jaw
Authors
K. Michaëlsson
J. Schilcher
P. Aspenberg
Publication date
01-12-2012
Publisher
Springer-Verlag
Published in
Osteoporosis International / Issue 12/2012
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-012-1905-1

Other articles of this Issue 12/2012

Osteoporosis International 12/2012 Go to the issue

Original Article

Poor bone microarchitecture in older men with impaired physical performance—the STRAMBO study

Review

Osteoporosis in young adults: pathophysiology, diagnosis, and management

Original Article

Age-related changes in proximal humerus bone health in healthy, white males

Original Article

Delay from fracture to hospital admission: a new risk factor for hip fracture mortality?

Original Article

Predictive factors of change in BMD at 1 and 2 years in women with anorexia nervosa: a study of 146 cases

Original Article

Effects of morning vs. evening teriparatide injection on bone mineral density and bone turnover markers in postmenopausal osteoporosis