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Published in:

01-10-2008 | Symposium Paper

Combined modality immunotherapy and chemotherapy: a new perspective

Authors: Rupal Ramakrishnan, Scott Antonia, Dmitry I. Gabrilovich

Published in: Cancer Immunology, Immunotherapy | Issue 10/2008

Abstract

The results of recent clinical trials have demonstrated that cancer vaccines continue to struggle to achieve tangible clinical benefits as monotherapy. Tumor-induced abnormalities in the immune system hamper anti-tumor T cell responses limiting the effectiveness of cancer immunotherapy. Recently, evidence has been mounting to suggest that immunotherapy has the possibility of achieving better success when used in combination with conventional chemotherapy. In clinical trials, immune responses elicited by cancer vaccines appear to augment the effectiveness of subsequent conventional cancer therapies.

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Title: Combined modality immunotherapy and chemotherapy: a new perspective
Authors: Rupal Ramakrishnan
Scott Antonia
Dmitry I. Gabrilovich
Publication date: 01-10-2008
Publisher: Springer-Verlag
Published in: Cancer Immunology, Immunotherapy / Issue 10/2008
Print ISSN: 0340-7004
Electronic ISSN: 1432-0851
DOI: https://doi.org/10.1007/s00262-008-0531-4

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