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28-03-2023 | Coma | Ethical Matters

Ethics Along the Continuum of Research Involving Persons with Disorders of Consciousness

Authors: Ariane Lewis, Michael J. Young, Benjamin Rohaut, Ralf J. Jox, Jan Claassen, Claire J. Creutzfeldt, Judy Illes, Matthew Kirschen, Stephen Trevick, Joseph J. Fins, and The Curing Coma Campaign and its Contributing Members

Published in: Neurocritical Care | Issue 3/2023

Abstract

Interest in disorders of consciousness (DoC) has grown substantially over the past decade and has illuminated the importance of improving understanding of DoC biology; care needs (use of monitoring, performance of interventions, and provision of emotional support); treatment options to promote recovery; and outcome prediction. Exploration of these topics requires awareness of numerous ethics considerations related to rights and resources. The Curing Coma Campaign Ethics Working Group used its expertise in neurocritical care, neuropalliative care, neuroethics, neuroscience, philosophy, and research to formulate an informal review of ethics considerations along the continuum of research involving persons with DoC related to the following: (1) study design; (2) comparison of risks versus benefits; (3) selection of inclusion and exclusion criteria; (4) screening, recruitment, and enrollment; (5) consent; (6) data protection; (7) disclosure of results to surrogates and/or legally authorized representatives; (8) translation of research into practice; (9) identification and management of conflicts of interest; (10) equity and resource availability; and (11) inclusion of minors with DoC in research. Awareness of these ethics considerations when planning and performing research involving persons with DoC will ensure that the participant rights are respected while maximizing the impact and meaningfulness of the research, interpretation of outcomes, and communication of results.

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Title: Ethics Along the Continuum of Research Involving Persons with Disorders of Consciousness
Authors: Ariane Lewis
Michael J. Young
Benjamin Rohaut
Ralf J. Jox
Jan Claassen
Claire J. Creutzfeldt
Judy Illes
Matthew Kirschen
Stephen Trevick
Joseph J. Fins
and The Curing Coma Campaign and its Contributing Members
Publication date: 28-03-2023
Publisher: Springer US
Keyword: Coma
Published in: Neurocritical Care / Issue 3/2023
Print ISSN: 1541-6933
Electronic ISSN: 1556-0961
DOI: https://doi.org/10.1007/s12028-023-01708-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Ethics Along the Continuum of Research Involving Persons with Disorders of Consciousness

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Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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