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01-08-2014 | Original Article

Colorectal carcinoma in first decade of life: our experience

Authors: M. A. Mushfiqur Rahman, Tanvir K. Chowdhury, Md. Akbar Husain Bhuiyan, Md. Abdullah Al Farooq, Md. Minhajuddin Sajid, Tahmina Banu

Published in: Pediatric Surgery International | Issue 8/2014

Abstract

Introduction

Though the lifetime risk of colorectal carcinoma (CRC) in general population is 5–6 %, it is uncommon in pediatric age group. Here, we are reporting our experience of CRC in the first decade of life.

Methods

From January 2010 to December 2013, seven patients with histopathologically confirmed colorectal carcinoma were treated in the Department of Pediatric Surgery, Chittagong Medical College and hospital. Age, sex, presenting symptoms, location of the primary tumor, serum CEA level, treatment modalities and outcomes were evaluated.

Results

There were four male and three female patients and age ranged from 6.5 to 10.5 years. Rectum (3 patients) and rectosigmoid (2 patients) were the most common primary sites. Serum carcinoembryonic antigen level was obtained in six patients and in only one patient the level was raised markedly (137 ng/ml). Two patients of familial adenomatous polyposis had localized disease and others presented in an advanced stage. Histopathologically, poorly differentiated adenocarcinoma was noted in five patients with one signet ring cell type and well differentiated in rest of the two patients. Only one patient was surviving at the last follow up.

Conclusion

Advanced stage at diagnosis, aggressive histologic subtype and poor survival are the hallmarks of pediatric CRC.

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Title: Colorectal carcinoma in first decade of life: our experience
Authors: M. A. Mushfiqur Rahman
Tanvir K. Chowdhury
Md. Akbar Husain Bhuiyan
Md. Abdullah Al Farooq
Md. Minhajuddin Sajid
Tahmina Banu
Publication date: 01-08-2014
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Surgery International / Issue 8/2014
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI: https://doi.org/10.1007/s00383-014-3537-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Colorectal carcinoma in first decade of life: our experience

Abstract

Introduction

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusion

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