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Open Access 09-02-2023 | Colorectal Cancer | Original Article

The global, regional, and national burden of colorectal cancer in 204 countries and territories from 1990 to 2019

Authors: Zhou Wu, Ke Chen, Jianjiong Li, Xiaoyu Dai

Published in: Journal of Public Health | Issue 4/2024

Abstract

Background

We aimed to estimate the global burden of colorectal cancer (CRC) between 1990 and 2019.

Methods

Data were extracted from the Global Burden of Disease study 2019. Estimated annual percentage changes (EAPCs) were calculated to quantify temporal trends in the age-standardized rates of CRC incidence, deaths, and disability-adjusted life-years (DALYs) by age, sex, region, and country. The correlations of EAPCs in the age-standardized rates with sociodemographic index (SDI) were also analyzed.

Results

From 1990 to 2019, the CRC incidence, deaths, and DALYs increased worldwide by 157%, 110%, and 96%, respectively. The global age-standardized incidence rate increased (EAPC, 0.58; 95% confidence interval [CI], 0.51–0.66), whereas both the age-standardized death rate (EAPC, −0.21; 95% CI, −0.28 to −0.14) and age-standardized DALY rate (EAPC, −0.21; 95% CI, −0.26 to −0.15) presented downward trends. As for regions, the largest increases in the age-standardized incidence rate, age-standardized death rate, and age-standardized DALY rate were observed in East Asia. In terms of countries, the largest increase in CRC incidence was found in Equatorial Guinea (3.98), followed by Vietnam (3.79) and China (3.66). The age-standardized incidence rate was higher in men than in women. Negative correlations were found between the EAPC in the age-standardized incidence rate of CRC and the SDI.

Conclusions

Future CRC preventive strategies should focus on the male population and older adults, especially in East Asia, Qatar, United Arab Emirates, Saudi Arabia, and other high-risk regions.

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Title: The global, regional, and national burden of colorectal cancer in 204 countries and territories from 1990 to 2019
Authors: Zhou Wu
Ke Chen
Jianjiong Li
Xiaoyu Dai
Publication date: 09-02-2023
Publisher: Springer Berlin Heidelberg
Keywords: Colorectal Cancer
Colorectal Cancer
Published in: Journal of Public Health / Issue 4/2024
Print ISSN: 2198-1833
Electronic ISSN: 1613-2238
DOI: https://doi.org/10.1007/s10389-023-01831-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The global, regional, and national burden of colorectal cancer in 204 countries and territories from 1990 to 2019

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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