Skip to main content
Top
Published in: International Journal of Colorectal Disease 4/2019

01-04-2019 | Colonoscopy | Original Article

Appendix orifice polyps: a study of 691 lesions at a single institution

Authors: Tarek H. Hassab, James M. Church

Published in: International Journal of Colorectal Disease | Issue 4/2019

Login to get access

Abstract

Purpose

Data on the management of appendix orifice lesions are limited. We present our experience on the management of appendix orifice lesions focusing on the range of size, histology, treatment, and outcomes for polyps at the appendix orifice.

Methods

Retrospective descriptive study at a tertiary referral center. Patients: Those having appendix orifice lesion removed and sent for histology between 2000 and 2017. Interventions(s): Polypectomy, surgery. Main outcome measures: Polyp size, shape, histology, treatment.

Results

In total, 691 patients matched our inclusion criteria. Screening was the most common indication for colonoscopy (49.1%). Mean size was 10.1 mm. The most common excision method was cold biopsy forceps (36.3%), followed by hot snare (9.3%), cold snare (8.5%), jumbo cold forceps (6.7%), hot biopsy (6.8%), and endoscopic mucosal resection (EMR)/endoscopic submucosal dissection (ESD) (4%). Recurrence was seen in 19/184 (10.3%) patients. Index polyps ≥ 10 mm had a significantly higher risk of recurrence compared to those ≤ 5 mm (odds ratio 3.2 95% CI 1.1–9.2, p = 0.027). None of the patients had complications. Surgery was performed in 45/691 (6.5%). Polyps > 5 mm (41/45) were more likely to require surgery than polyps ≤ 5 mm (4/45 6.67%), p < 0.001.

Limitations

Retrospective study.

Conclusion

Appendix orifice polyps can usually be managed by conventional endoscopic polypectomy methods without the need for ESD.
Literature
1.
go back to reference Ro TH, Mathew MA, Misra S (2015) Value of screening endoscopy in evaluation of esophageal, gastric and colon cancers. World J Gastroenterol 21(33):9693–9706CrossRefPubMedPubMedCentral Ro TH, Mathew MA, Misra S (2015) Value of screening endoscopy in evaluation of esophageal, gastric and colon cancers. World J Gastroenterol 21(33):9693–9706CrossRefPubMedPubMedCentral
2.
go back to reference Singh N, Harrison M, Rex DK (2004) A survey of colonoscopic polypectomy practices among clinical gastroenterologists. Gastrointest Endosc 60(3):414–418CrossRefPubMed Singh N, Harrison M, Rex DK (2004) A survey of colonoscopic polypectomy practices among clinical gastroenterologists. Gastrointest Endosc 60(3):414–418CrossRefPubMed
4.
go back to reference Draganov PV, Gotoda T, Chavalitdhamrong D, Wallace MB (2013) Techniques of endoscopic submucosal dissection: application for the Western endoscopist? Gastrointest Endosc 78(5):677–688CrossRefPubMed Draganov PV, Gotoda T, Chavalitdhamrong D, Wallace MB (2013) Techniques of endoscopic submucosal dissection: application for the Western endoscopist? Gastrointest Endosc 78(5):677–688CrossRefPubMed
5.
go back to reference Hori K, Uraoka T, Harada K, Higashi R, Kawahara Y, Okada H, Ramberan H, Yahagi N, Yamamoto K (2014) Predictive factors for technically difficult endoscopic submucosal dissection in the colorectum. Endoscopy 46(10):862–870CrossRefPubMed Hori K, Uraoka T, Harada K, Higashi R, Kawahara Y, Okada H, Ramberan H, Yahagi N, Yamamoto K (2014) Predictive factors for technically difficult endoscopic submucosal dissection in the colorectum. Endoscopy 46(10):862–870CrossRefPubMed
6.
go back to reference Song EM, Yang HJ, Lee HJ, Lee HS, Cha JM, Kim HG, Jung Y, Moon CM, Kim BC, Byeon JS (2017) Endoscopic resection of cecal polyps involving the appendiceal orifice: a KASID multicenter study. Dig Dis Sci 62(11):3138–3148CrossRefPubMed Song EM, Yang HJ, Lee HJ, Lee HS, Cha JM, Kim HG, Jung Y, Moon CM, Kim BC, Byeon JS (2017) Endoscopic resection of cecal polyps involving the appendiceal orifice: a KASID multicenter study. Dig Dis Sci 62(11):3138–3148CrossRefPubMed
7.
go back to reference Jacob H, Toyonaga T, Ohara Y, Tsubouchi E, Takihara H, Baba S, Yoshizaki T, Kawara F, Tanaka S, Ishida T, Hoshi N, Morita Y, Umegaki E, Azuma T (2016) Endoscopic submucosal dissection of cecal lesions in proximity to the appendiceal orifice. Endoscopy 48(9):829–836CrossRefPubMed Jacob H, Toyonaga T, Ohara Y, Tsubouchi E, Takihara H, Baba S, Yoshizaki T, Kawara F, Tanaka S, Ishida T, Hoshi N, Morita Y, Umegaki E, Azuma T (2016) Endoscopic submucosal dissection of cecal lesions in proximity to the appendiceal orifice. Endoscopy 48(9):829–836CrossRefPubMed
8.
go back to reference Martinez ME, Sampliner R, Marshall JR, Bhattacharyya AK, Reid ME, Alberts DS (2001) Adenoma characteristics as risk factors for recurrence of advanced adenomas. Gastroenterology 120(5):1077–1083CrossRefPubMed Martinez ME, Sampliner R, Marshall JR, Bhattacharyya AK, Reid ME, Alberts DS (2001) Adenoma characteristics as risk factors for recurrence of advanced adenomas. Gastroenterology 120(5):1077–1083CrossRefPubMed
9.
go back to reference Bonithon-Kopp C, Piard F, Fenger C, Cabeza E, O'Morain C, Kronborg O, Faivre J, European Cancer Prevention Organisation Study Group (2004) Colorectal adenoma characteristics as predictors of recurrence. Dis Colon Rectum 47(3):323–333CrossRefPubMed Bonithon-Kopp C, Piard F, Fenger C, Cabeza E, O'Morain C, Kronborg O, Faivre J, European Cancer Prevention Organisation Study Group (2004) Colorectal adenoma characteristics as predictors of recurrence. Dis Colon Rectum 47(3):323–333CrossRefPubMed
10.
go back to reference Young-Fadok TM (2009) Pro: a large colonic polyp is best removed by laparoscopy. Am J Gastroenterol 104(2):270–272CrossRefPubMed Young-Fadok TM (2009) Pro: a large colonic polyp is best removed by laparoscopy. Am J Gastroenterol 104(2):270–272CrossRefPubMed
11.
go back to reference Church JM (2009) Laparoscopic vs. colonoscopic removal of a large polyp. Am J Gastroenterol 104(10):2633–2634CrossRefPubMed Church JM (2009) Laparoscopic vs. colonoscopic removal of a large polyp. Am J Gastroenterol 104(10):2633–2634CrossRefPubMed
12.
go back to reference Soetikno R, Gotoda T (2009) Con: colonoscopic resection of large neoplastic lesions is appropriate and safe. Am J Gastroenterol 104(2):272–275CrossRefPubMed Soetikno R, Gotoda T (2009) Con: colonoscopic resection of large neoplastic lesions is appropriate and safe. Am J Gastroenterol 104(2):272–275CrossRefPubMed
Metadata
Title
Appendix orifice polyps: a study of 691 lesions at a single institution
Authors
Tarek H. Hassab
James M. Church
Publication date
01-04-2019
Publisher
Springer Berlin Heidelberg
Published in
International Journal of Colorectal Disease / Issue 4/2019
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI
https://doi.org/10.1007/s00384-019-03251-z

Other articles of this Issue 4/2019

International Journal of Colorectal Disease 4/2019 Go to the issue