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International Journal of Colorectal Disease
Published in: International Journal of Colorectal Disease 1/2024

Open Access 01-12-2024 | Colon Cancer | RESEARCH

Short- and long-term outcome differences between patients undergoing left and right colon cancer surgery: cohort study

Authors: Justas Kuliavas, Kristina Marcinkevičiūtė, Augustinas Baušys, Klaudija Bičkaitė, Rimantas Baušys, Vilius Abeciūnas, Austėja Elžbieta Degutytė, Marius Kryžauskas, Eugenijus Stratilatovas, Audrius Dulskas, Tomas Poškus, Kęstutis Strupas

Published in: International Journal of Colorectal Disease | Issue 1/2024

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Abstract

Purpose

Since the literature currently provides controversial data on the postoperative outcomes following right and left hemicolectomies, we carried out this study to examine the short- and long-term treatment outcomes.

Methods

This study included consecutive patients who underwent right or left-sided colonic resections from year 2014 to 2018 and then they were followed up. The short-term outcomes such as postoperative morbidity and mortality according to Clavien-Dindo score, duration of hospital stay, and 90-day readmission rate were evaluated as well as long-term outcomes of overall survival and disease-free survival. Multivariable Cox regression analysis was performed of overall and progression-free survival.

Results

In total, 1107 patients with colon tumors were included in the study, 525 patients with right-sided tumors (RCC) and 582 cases with tumors in the left part of the colon (LCC). RCC group patients were older (P < 0.001), with a higher ASA score (P < 0.001), and with more cardiovascular comorbidities (P < 0.001). No differences were observed between groups in terms of postoperative outcomes such as morbidity and mortality, except 90-day readmission which was more frequent in the RCC group. Upon histopathological analysis, the RCC group’s patients had more removed lymph nodes (29 ± 14 vs 20 ± 11, P = 0.001) and more locally progressed (pT3-4) tumors (85.4% versus 73.4%, P = 0.001). Significantly greater 5-year overall survival and disease-free survival (P = 0.001) were observed for patients in the LCC group, according to univariate Kaplan-Meier analysis.

Conclusions

Patients with right-sided colon cancer were older and had more advanced disease. Short-term surgical outcomes were similar, but patients in the LCC group resulted in better long-term outcomes.
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Metadata
Title
Short- and long-term outcome differences between patients undergoing left and right colon cancer surgery: cohort study
Authors
Justas Kuliavas
Kristina Marcinkevičiūtė
Augustinas Baušys
Klaudija Bičkaitė
Rimantas Baušys
Vilius Abeciūnas
Austėja Elžbieta Degutytė
Marius Kryžauskas
Eugenijus Stratilatovas
Audrius Dulskas
Tomas Poškus
Kęstutis Strupas
Publication date
01-12-2024
Publisher
Springer Berlin Heidelberg
Published in
International Journal of Colorectal Disease / Issue 1/2024
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI
https://doi.org/10.1007/s00384-024-04623-w

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