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Surgery Today
Published in: Surgery Today 3/2021

01-03-2021 | Colectomy | Original Article

Oncological outcomes following laparoscopic surgery for pathological T4 colon cancer: a propensity score-matched analysis

Authors: Toshinori Sueda, Mitsuyoshi Tei, Kentaro Nishida, Yukihiro Yoshikawa, Tae Matsumura, Chikato Koga, Masaki Wakasugi, Hiromichi Miyagaki, Ryohei Kawabata, Masanori Tsujie, Junichi Hasegawa

Published in: Surgery Today | Issue 3/2021

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Abstract

Purposes

Whether laparoscopic colectomy (LC) is safe and effective for patients with locally advanced T4 colon cancer remains controversial. This study aimed to compare the oncological outcomes of LC and open colectomy (OC) for patients with pathological (p) T4 colon cancer.

Methods

We retrospectively analyzed 151 consecutive patients with pT4M0 colon cancer who underwent curative surgery between 2010 and 2017 using a propensity score-matched analysis.

Results

After propensity score-matching, we enrolled 100 patients (n = 50 in each group). Median follow-up was 43.5 months. The conversion rate to laparotomy in this study was 5.5% for the entire patient cohort and 6.0% for the matched cohort. Compared to the OC group, the LC group showed reductions in estimated blood loss and length of postsurgical stay. Clavien–Dindo classification grade ≥ II and all-grade complication rates were significantly lower in the LC group than in the OC group. R0 resection was achieved in all patients with LC. No significant differences were found between the groups in terms of overall, cancer-specific, recurrence-free survival, or incidence of local recurrence among the entire patient cohort and matched cohort.

Conclusions

The oncological outcomes were similar between the LC and OC groups. LC offers a safe, feasible option for patients with pT4 colon cancer.
Appendix
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Metadata
Title
Oncological outcomes following laparoscopic surgery for pathological T4 colon cancer: a propensity score-matched analysis
Authors
Toshinori Sueda
Mitsuyoshi Tei
Kentaro Nishida
Yukihiro Yoshikawa
Tae Matsumura
Chikato Koga
Masaki Wakasugi
Hiromichi Miyagaki
Ryohei Kawabata
Masanori Tsujie
Junichi Hasegawa
Publication date
01-03-2021
Publisher
Springer Singapore
Published in
Surgery Today / Issue 3/2021
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-020-02106-3

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