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Osteoporosis International

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01-01-2014 | Original Article

Coffee, tea, and the risk of hip fracture: a meta-analysis

Authors: J. Sheng, X. Qu, X. Zhang, Z. Zhai, H. Li, X. Liu, H. Li, G. Liu, Z. Zhu, Y. Hao, A. Qin, K. Dai

Published in: Osteoporosis International | Issue 1/2014

Abstract

Summary

The present meta-analysis shows no clear association between coffee consumption and the risk of hip fractures. There was a nonlinear association between tea consumption and the risk of hip fracture. Compared to no tea consumption, drinking 1−4 cups of tea daily was associated with a lower risk of hip fracture.

Introduction

Prospective cohort and case–control studies have suggested that coffee and tea consumption may be associated with the risk of hip fracture; the results have, however, been inconsistent. We conducted a meta-analysis to assess the association between coffee and tea consumption and the risk of hip fracture.

Methods

We performed systematic searches using MEDLINE, EMBASE, and OVID until February 20, 2013, without limits of language or publication year. Relative risks (RRs) with 95 % confidence intervals (CI) were derived using random-effects models throughout all analyses. We conducted categorical, dose–response, heterogeneity, publication bias, and subgroup analyses.

Results

Our study was based on 195,992 individuals with 9,958 cases of hip fractures from 14 studies, including six cohort and eight case–control studies. The pooled RRs of hip fractures for the highest vs. the lowest categories of coffee and tea consumption were 0.94 (95 % CI 0.71–1.17) and 0.84 (95 % CI 0.66–1.02), respectively. For the dose–response analysis, we found evidence of a nonlinear association between tea consumption and the risk of hip fracture (p _nonlinearity < 0.01). Compared to no tea consumption, 1–4 cups of tea per day may reduce the risk of hip fracture by 28 % (0.72; 95 % CI 0.56–0.88 for 1–2 cups/day), 37 % (0.63; 95 % CI 0.32–0.94 for 2–3 cups/day), and 21 % (0.79; 95 % CI 0.62–0.96 for 3–4 cups/day).

Conclusions

We found no significant association between coffee consumption and the risk of hip fracture. A nonlinear association emerged between tea consumption and the risk of hip fracture; individuals drinking 1–4 cups of tea per day exhibited a lower risk of hip fractures than those who drank no tea. The association between 5 daily cups of tea, or more, and hip fracture risk should be investigated.

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Title: Coffee, tea, and the risk of hip fracture: a meta-analysis
Authors: J. Sheng
X. Qu
X. Zhang
Z. Zhai
H. Li
X. Liu
H. Li
G. Liu
Z. Zhu
Y. Hao
A. Qin
K. Dai
Publication date: 01-01-2014
Publisher: Springer London
Published in: Osteoporosis International / Issue 1/2014
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI: https://doi.org/10.1007/s00198-013-2563-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Coffee, tea, and the risk of hip fracture: a meta-analysis

Abstract

Summary

Introduction

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Summary

Introduction

Methods

Results

Conclusions

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