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Open Access 01-07-2012 | Brief Report

Cluster-tic syndrome as the initial manifestation of multiple sclerosis

Authors: V. González-Quintanilla, A. Oterino, M. Toriello, C. de Pablos, Y. Wu, E. de Marco, J. Pascual

Published in: The Journal of Headache and Pain | Issue 5/2012

Abstract

We report the case of a patient diagnosed as having cluster-tic syndrome as the initial manifestation of multiple sclerosis (MS). The patient’s headache bouts improved after treatment with antiepileptic drugs, steroids, and beta-interferon. Magnetic resonance imaging (MRI) scans showed a pontine demyelinating lesion involving the area of the trigeminal root inlet and main sensory nucleus. Neurophysiological studies correlated well with MRI lesions. The association between cluster-tic syndrome and MS is an exception, and the mechanism of the pain is still unknown; therefore, this case might suggest a pathophysiological relationship between the trigeminal main sensory nucleus and cluster-tic syndrome.

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Title: Cluster-tic syndrome as the initial manifestation of multiple sclerosis
Authors: V. González-Quintanilla
A. Oterino
M. Toriello
C. de Pablos
Y. Wu
E. de Marco
J. Pascual
Publication date: 01-07-2012
Publisher: Springer Milan
Published in: The Journal of Headache and Pain / Issue 5/2012
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI: https://doi.org/10.1007/s10194-012-0449-2

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