Clostridium perfringens related spleen gangrene

Excerpt

A 48-year-old man with no previous medical history was admitted to the intensive care unit for febrile dyspnoea and abdominal pain. Abdominal palpation disclosed pain of the left flank without guarding. There was no evidence of disseminated intravascular coagulation or intravascular haemolysis. Echocardiography revealed an enlarged right ventricle without evidence of patent foramen ovale. Thoracoabdominal CT scan revealed bilateral pulmonary embolism, non-occlusive thrombi of coeliac, superior mesenteric and splenic arteries with an intra-splenic gaseous collection (Fig. 1). No peritoneal effusion was noticed during laparoscopic splenectomy, but surgeons reported a foul-smelling odour. Splenic samples were positive for Clostridium perfringens.

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