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Published in: Critical Care 5/2010

01-10-2010 | Journal club critique

Clostridium difficile: moving beyond antimicrobial therapy

Authors: Amesh A Adalja, John A Kellum

Published in: Critical Care | Issue 5/2010

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Excerpt

Lowy I, Molrine DC, Leav BA, Blair BM, Baxter R, Gerding DN, Nichol G, Thomas WD Jr, Leney M, Sloan S, Hay CA, Ambrosino DM: Treatment with monoclonal antibodies against Clostridium difficile toxins. N Engl J Med 2010, 362:197-205. …
Literature
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go back to reference Dubberke ER, Butler AM, Reske KA, Agniel D, Olsen MA, D'Angelo G, McDonald LC, Fraser VJ: Attributable outcomes of endemic Clostridium difficile-associated disease in nonsurgical patients. Emerg Infect Dis 2008, 14: 1031-1038. 10.3201/eid1407.070867PubMedCentralCrossRefPubMed Dubberke ER, Butler AM, Reske KA, Agniel D, Olsen MA, D'Angelo G, McDonald LC, Fraser VJ: Attributable outcomes of endemic Clostridium difficile-associated disease in nonsurgical patients. Emerg Infect Dis 2008, 14: 1031-1038. 10.3201/eid1407.070867PubMedCentralCrossRefPubMed
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go back to reference Dubberke ER, Reske KA, Olsen MA, McDonald LC, Fraser VJ: Short- and long-term attributable costs of Clostridium difficile-associated disease in nonsurgical inpatients. Clin Infect Dis 2008, 46: 497-504. 10.1086/526530CrossRefPubMed Dubberke ER, Reske KA, Olsen MA, McDonald LC, Fraser VJ: Short- and long-term attributable costs of Clostridium difficile-associated disease in nonsurgical inpatients. Clin Infect Dis 2008, 46: 497-504. 10.1086/526530CrossRefPubMed
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go back to reference Garey KW, Sethi S, Yadav Y, DuPont HL: Meta-analysis to assess risk factors for recurrent Clostridium difficile infection. J Hosp Infect 2008, 70: 298-304. 10.1016/j.jhin.2008.08.012CrossRefPubMed Garey KW, Sethi S, Yadav Y, DuPont HL: Meta-analysis to assess risk factors for recurrent Clostridium difficile infection. J Hosp Infect 2008, 70: 298-304. 10.1016/j.jhin.2008.08.012CrossRefPubMed
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go back to reference Lowy I, Molrine DC, Leav BA, Blair BM, Baxter R, Gerding DN, Nichol G, Thomas WD Jr, Leney M, Sloan S, Hay CA, Ambrosino DM: Treatment with monoclonal antibodies against Clostridium difficile toxins. N Engl J Med 2010, 362: 197-205. 10.1056/NEJMoa0907635CrossRefPubMed Lowy I, Molrine DC, Leav BA, Blair BM, Baxter R, Gerding DN, Nichol G, Thomas WD Jr, Leney M, Sloan S, Hay CA, Ambrosino DM: Treatment with monoclonal antibodies against Clostridium difficile toxins. N Engl J Med 2010, 362: 197-205. 10.1056/NEJMoa0907635CrossRefPubMed
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go back to reference Kyne L: Clostridium difficile--beyond antibiotics. N Engl J Med 2010, 362: 264-265. 10.1056/NEJMe0910055CrossRefPubMed Kyne L: Clostridium difficile--beyond antibiotics. N Engl J Med 2010, 362: 264-265. 10.1056/NEJMe0910055CrossRefPubMed
Metadata
Title
Clostridium difficile: moving beyond antimicrobial therapy
Authors
Amesh A Adalja
John A Kellum
Publication date
01-10-2010
Publisher
BioMed Central
Published in
Critical Care / Issue 5/2010
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc9249

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