Skip to main content
Top
Published in: Journal of Gastrointestinal Surgery 1/2010

01-01-2010 | Original Article

Clinicopathological Properties of the Superficial Spreading Type Early Gastric Cancer

Authors: Tsutomu Namikawa, Hiroyuki Kitagawa, Jun Iwabu, Takehiro Okabayashi, Takeki Sugimoto, Michiya Kobayashi, Kazuhiro Hanazaki

Published in: Journal of Gastrointestinal Surgery | Issue 1/2010

Login to get access

Abstract

Introduction

We investigated differences in characteristics between the superficial spreading type early gastric cancer (EGC) characterized by a wide and superficial extension and the common type EGC.

Patients and Methods

Between 1982 and 2008, we retrospectively reviewed clinical reports of patients with the EGC treated at Kochi Medical School.

Results

Sixty-one patients (9.6%) out of 646 patients had the superficial spreading type EGC. The occurrences of diffuse type histology and lymph node metastasis were significantly greater in the superficial spreading type than in the common type. The incidence of EGC confined to the mucosa was significantly greater in the lymph node-positive superficial spreading type than in the lymph node-positive common type.

Conclusions

In patients with the superficial spreading type EGC, lymph node metastasis was more prominent regardless of the degree of tumor invasion. Therefore, appropriate extensive lymph node dissection and wide surgical resection are required for the curative resection of the superficial spreading type EGC.
Literature
3.
4.
go back to reference Golden R, Stout AP. Superficial spreading carcinoma of the stomach. Am J Roentgenol Radium Ther 1948;59:157–167.PubMed Golden R, Stout AP. Superficial spreading carcinoma of the stomach. Am J Roentgenol Radium Ther 1948;59:157–167.PubMed
5.
go back to reference Yasui A, Hirase Y, Miyake M, Kidokoro T, Murakami T. Pathology of superficial spreading type of gastric cancer. Stomach and Intestine 1973;8:1305–1310. Yasui A, Hirase Y, Miyake M, Kidokoro T, Murakami T. Pathology of superficial spreading type of gastric cancer. Stomach and Intestine 1973;8:1305–1310.
6.
go back to reference Japanese Gastric Cancer Association. Japanese classification of gastric carcinoma: 2nd English edition. Gastric Cancer 1998;1:10–24.CrossRefPubMed Japanese Gastric Cancer Association. Japanese classification of gastric carcinoma: 2nd English edition. Gastric Cancer 1998;1:10–24.CrossRefPubMed
7.
go back to reference Lauren P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histoclinical classification. Acta Pathol Microbiol Scand 1965;64:31–49.PubMed Lauren P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histoclinical classification. Acta Pathol Microbiol Scand 1965;64:31–49.PubMed
8.
9.
go back to reference Imai M, Kondo Y, Osawa S, Nishida Y, Okada K, Ishizu H, Masuko H, Hata T, Uemura K, Kina M, Honda S, Ishiyama G, Takahashi T, Hino A. Clinicopathological characteristics of superficial spreading type early gastric cancer. J Surg Oncol 2003;83:94–98. doi:10.1002/jso.10229.CrossRefPubMed Imai M, Kondo Y, Osawa S, Nishida Y, Okada K, Ishizu H, Masuko H, Hata T, Uemura K, Kina M, Honda S, Ishiyama G, Takahashi T, Hino A. Clinicopathological characteristics of superficial spreading type early gastric cancer. J Surg Oncol 2003;83:94–98. doi:10.​1002/​jso.​10229.CrossRefPubMed
10.
11.
go back to reference Kitamura K, Yamaguchi T, Okamoto K, Nishida T, Takahashi T. Superficial spreading type of early gastric cancer. Br J Cancer 1996;74:1834–1837.PubMed Kitamura K, Yamaguchi T, Okamoto K, Nishida T, Takahashi T. Superficial spreading type of early gastric cancer. Br J Cancer 1996;74:1834–1837.PubMed
12.
go back to reference Yokota T, Ishiyama S, Saito T, Teshima S, Narushima Y, Murata K, Iwamoto K, Yashima R, Yamauchi H, Kikuchi S. Lymph node metastasis as a significant prognostic factor in gastric cancer: a multiple logistic regression analysis. Scand J Gastroenterol 2004;39:380–384. doi:10.1080/00365520310008629.CrossRefPubMed Yokota T, Ishiyama S, Saito T, Teshima S, Narushima Y, Murata K, Iwamoto K, Yashima R, Yamauchi H, Kikuchi S. Lymph node metastasis as a significant prognostic factor in gastric cancer: a multiple logistic regression analysis. Scand J Gastroenterol 2004;39:380–384. doi:10.​1080/​0036552031000862​9.CrossRefPubMed
14.
15.
go back to reference Yokota T, Ishiyama S, Saito T, Teshima S, Yamada Y, Iwamoto K, Takahashi M, Murata K, Yamauchi H. Is tumor size a prognostic indicator for gastric carcinoma? Anticancer Res 2002;22:3673–3677.PubMed Yokota T, Ishiyama S, Saito T, Teshima S, Yamada Y, Iwamoto K, Takahashi M, Murata K, Yamauchi H. Is tumor size a prognostic indicator for gastric carcinoma? Anticancer Res 2002;22:3673–3677.PubMed
16.
go back to reference Kunisaki C, Makino H, Takagawa R, Oshima T, Nagano Y, Kosaka T, Ono HA, Otsuka Y, Akiyama H, Ichikawa Y, Shimada H. Tumor diameter as a prognostic factor in patients with gastric cancer. Ann Surg Oncol 2008;15:1959–1967. doi:10.1245/s10434-008-9884-3.CrossRefPubMed Kunisaki C, Makino H, Takagawa R, Oshima T, Nagano Y, Kosaka T, Ono HA, Otsuka Y, Akiyama H, Ichikawa Y, Shimada H. Tumor diameter as a prognostic factor in patients with gastric cancer. Ann Surg Oncol 2008;15:1959–1967. doi:10.​1245/​s10434-008-9884-3.CrossRefPubMed
19.
go back to reference Namikawa T, Kobayashi M, Kitagawa H, Okabayashi T, Sugimoto T, Kuratani Y, Matsumoto M, Hanazaki K. Differentiated adenocarcinoma with a gastric phenotype in the stomach: difficulties in clinical and pathological diagnoses. Clin J Gastroenterol 2009;2:268–274. doi:10.1007/s12328-009-0090-z.CrossRef Namikawa T, Kobayashi M, Kitagawa H, Okabayashi T, Sugimoto T, Kuratani Y, Matsumoto M, Hanazaki K. Differentiated adenocarcinoma with a gastric phenotype in the stomach: difficulties in clinical and pathological diagnoses. Clin J Gastroenterol 2009;2:268–274. doi:10.​1007/​s12328-009-0090-z.CrossRef
20.
go back to reference Yoshimura Y, Yasutake K, Imamura Y, Sashikata T, Oimomi M. Endoscopic studies on the superficial spreading type of early gastric cancer. Kobe J Med Sci 1989;35:29–38.PubMed Yoshimura Y, Yasutake K, Imamura Y, Sashikata T, Oimomi M. Endoscopic studies on the superficial spreading type of early gastric cancer. Kobe J Med Sci 1989;35:29–38.PubMed
Metadata
Title
Clinicopathological Properties of the Superficial Spreading Type Early Gastric Cancer
Authors
Tsutomu Namikawa
Hiroyuki Kitagawa
Jun Iwabu
Takehiro Okabayashi
Takeki Sugimoto
Michiya Kobayashi
Kazuhiro Hanazaki
Publication date
01-01-2010
Publisher
Springer-Verlag
Published in
Journal of Gastrointestinal Surgery / Issue 1/2010
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-009-1059-4

Other articles of this Issue 1/2010

Journal of Gastrointestinal Surgery 1/2010 Go to the issue